LmxM.34.0030

pyruvate kinase, putative
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_100258 OG7: OG7_0002165 181 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 181 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.11.0210 ⚠
acidocalcisomal pyrophosphatase
— Both
LmxM.03.0910 ⚠
inorganic pyrophosphatase, putative
— Both
LmxM.14.1190 ⚠
Bifunctional NAD(P)H-hydrate repair enzyme
— Both
LmxM.18.1090 ⚠
phosphodiesterase, putative
— OG7
LmxM.03.0230 ⚠
long chain fatty Acyl CoA synthetase, putativ
— Both
LmxM.11.0620 ⚠
metallo-peptidase, Clan MF, Family M17
— Both
LmxM.34.0830 ⚠
NADH-dependent fumarate reductase-like protei
— Both
LmxM.20.1180 ⚠
calpain-like cysteine peptidase
— OG6
LmxM.01.0470 ⚠
fatty acyl CoA syntetase 1, putative
— Both
LmxM.34.1180 ⚠
NADH-dependent fumarate reductase, putative
— Both
LmxM.27.0930 ⚠
isovaleryl-coA dehydrogenase, putative
— Both
LmxM.18.1580 ⚠
nonspecific nucleoside hydrolase
— Both
LmxM.11.0630 ⚠
metallo-peptidase, Clan MF, Family M17
— Both
LmxM.13.1190 ⚠
adenylosuccinate synthetase, putative
— Both
LmxM.34.1190 ⚠
NADH-dependent fumarate reductase, putative
— Both
LmxM.07.0800 ⚠
flavoprotein subunit-like protein
— Both
LmxM.33.3380 ⚠
aldose 1-epimerase-like protein
— Both
LmxM.01.0500 ⚠
fatty acyl CoA synthetase 2, putative
— Both
LmxM.15.1440 ⚠
glutaminyl-tRNA synthetase, putative
— Both
LmxM.06.0860 ⚠
dihydrofolate reductase-thymidylate synthase
— Both
LmxM.29.1550 ⚠
pseudouridine synthase A-like protein, putati
— Both
LmxM.04.0450 ⚠
calpain-like cysteine peptidase, putative
— OG6
LmxM.01.0520 ⚠
long-chain-fatty-acid-CoA ligase, putative
— Both
LmxM.08_29.0867 ⚠
guanine deaminase, putative
— Both
LmxM.29.3500 ⚠
S-adenosylmethionine synthetase
— Both
LmxM.24.2060 ⚠
transketolase, putative
— Both
LmxM.15.1481 ⚠
cAMP specific phosphodiesterase, putative
— Both
LmxM.14.0130 ⚠
nucleoside hydrolase-like protein
— Both
LmxM.34.4750 ⚠
glyceraldehyde-3-phosphate dehydrogenase-like
— Both
LmxM.31.3260 ⚠
glucosamine-6-phosphate isomerase, putative,
— Both
LmxM.01.0490 ⚠
long-chain-fatty-acid-CoA ligase, putative
— Both
LmxM.20.1185 ⚠
calpain-like cysteine peptidase, putative
— OG6
LmxM.15.1480 ⚠
cAMP specific phosphodiesterase, putative
— Both
LmxM.06.1070 ⚠
deoxyribose-phosphate aldolase, putative
— Both
LmxM.33.3780 ⚠
phosphomannomutase-like protein
— Both
LmxM.30.1130 ⚠
amidohydrolase, putative
— Both
LmxM.20.1560 ⚠
amidohydrolase, putative
— Both
LmxM.29.1380 ⚠
amidohydrolase, putative
— Both
LmxM.20.1570 ⚠
amidohydrolase, putative
— Both
LmxM.20.1550 ⚠
amidohydrolase, putative
— Both
LmxM.28.2070 ⚠
tRNA threonylcarbamoyl adenosine modification
— Both
LmxM.01.0220 ⚠
cyclophilin type peptidyl-prolyl cis-trans is
— OG6
LmxM.27.0720 ⚠
UBA/TS-N domain containing protein, putative
— Both
LmxM.13.1610 ⚠
Kinesin-13 5, putative
— OG7
LmxM.30.0290 ⚠
Kinesin-13 4, putative
— OG7
LmxM.01.0030 ⚠
Kinesin-13 1, putative
— OG7
LmxM.28.1380 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LmxM.21.0150 ⚠
serine/threonine-protein kinase-like protein
— OG7
LmxM.21.0030 ⚠
hypothetical protein, conserved
— OG7
LmxM.22.0810 ⚠
serine/threonine protein kinase sos2, putativ
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.