LmxM.01.0490

long-chain-fatty-acid-CoA ligase, putative
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_100746 OG7: OG7_0001203 60 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 60 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.23.0460 ⚠
trypanothione synthetase, putative
— OG7
LmxM.28.1200 ⚠
luminal binding protein 1 (BiP), putative
— Both
LmxM.28.2820 ⚠
heat shock protein 70, putative
— OG6
LmxM.28.2770 ⚠
heat-shock protein hsp70, putative
— Both
LmxM.26.1240 ⚠
heat shock protein 70-related protein
— Both
LmxM.28.2780 ⚠
heat-shock protein hsp70, putative
— Both
LmxM.29.3500 ⚠
S-adenosylmethionine synthetase
— Both
LmxM.08_29.0740 ⚠
peroxisomal targeting signal 2 receptor, puta
— Both
LmxM.12.0530 ⚠
glucose-6-phosphate isomerase
— Both
LmxM.34.0030 ⚠
pyruvate kinase, putative
— Both
LmxM.34.0020 ⚠
pyruvate kinase
— Both
LmxM.29.3240 ⚠
glutamyl-tRNA synthetase, putative
— OG7
LmxM.32.2830 ⚠
D-alanyl-glycyl endopeptidase-like protein, p
— OG7
LmxM.32.2850 ⚠
D-alanyl-glycyl endopeptidase-like protein, p
— OG7
LmxM.25.2380 ⚠
glutathionylspermidine synthase, putative
— OG7
LmxM.26.1610 ⚠
Proline dehydrogenase, mitochondrial
— Both
LmxM.31.3970 ⚠
cAMP response protein 1, putative
— OG7
LmxM.32.0312 ⚠
heat shock protein 83-1
— OG7
LmxM.25.1060 ⚠
hypothetical protein, conserved
— OG7
LmxM.32.0316 ⚠
heat shock protein 83-1
— OG7
LmxM.32.0314 ⚠
heat shock protein 83-1
— OG7
LmxM.32.2390 ⚠
heat shock protein, putative
— OG7
LmxM.33.3500 ⚠
ruvb-like 1 DNA helicase, putative
— OG7
LmxM.13.0160 ⚠
protein kinase A regulatory subunit
— OG7
LmxM.08_29.0760 ⚠
heat shock protein 90, putative
— OG7
LmxM.15.1200 ⚠
protein kinase, putative
— OG7
LmxM.26.0900 ⚠
chaperone protein-like protein, heat shock 70
— OG7
LmxM.34.4710 ⚠
Hsp70 protein, putative
— OG7
LmxM.01.0640 ⚠
HSP70-like protein
— OG7
LmxM.18.1370 ⚠
heat shock protein, putative
— OG7
LmxM.34.1880 ⚠
60S ribosomal protein L5, putative
— Both
LmxM.27.1870 ⚠
trypanothione synthetase
— Both
LmxM.36.2350 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— Both
LmxM.29.2980 ⚠
glyceraldehyde 3-phosphate dehydrogenase, gly
— Both
LmxM.31.3010 ⚠
leucine-rich repeat protein, putative
— Both
LmxM.26.1980 ⚠
hypothetical protein, conserved
— OG6
LmxM.33.2820 ⚠
regulatory subunit of protein kinase a-like p
— Both
LmxM.21.1760 ⚠
centromere/microtubule binding protein cbf5,
— Both
LmxM.05.0180 ⚠
dihydrolipoamide branched chain transacylase,
— Both
LmxM.25.1420 ⚠
GTP-binding protein, putative
— Both
LmxM.33.2610 ⚠
ruvB-like DNA helicase, putative
— Both
LmxM.24.2060 ⚠
transketolase, putative
— Both
LmxM.08_29.2800 ⚠
inosine-adenosine-guanosine-nucleosidehydrola
— Both
LmxM.27.0930 ⚠
isovaleryl-coA dehydrogenase, putative
— Both
LmxM.34.1900 ⚠
60S ribosomal protein L5, putative
— Both
LmxM.13.1190 ⚠
adenylosuccinate synthetase, putative
— Both
LmxM.34.1890 ⚠
60S ribosomal protein L5, putative
— Both
LmxM.18.1580 ⚠
nonspecific nucleoside hydrolase
— Both
LmxM.14.0130 ⚠
nucleoside hydrolase-like protein
— Both
LmxM.27.2032 ⚠
branched-chain amino acid aminotransferase, p
— Both
Page 1 of 2
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.