LmxM.27.0860

WD domain, G-beta repeat, putative
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_200147 OG7: OG7_0063820 67 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 67 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.05.0970
mercaptopyruvate sulfurtransferase
— Both
LmxM.11.0400 ⚠
tubulin-tyrsoine ligase-like protein
— OG7
LmxM.16.0380 ⚠
tubulin tyrosine ligase, putative
— OG7
LmxM.29.2280 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LmxM.31.2930 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LmxM.08_29.0260 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LmxM.18.0370 ⚠
tubulin tyrosine ligase protein, putative
— OG7
LmxM.34.4930 ⚠
tubulin tyrosine ligase, putative
— OG7
LmxM.08.0300 ⚠
Isochorismatase family, putative
— OG7
LmxM.08.0310 ⚠
Isochorismatase family, putative
— OG7
LmxM.13.0160 ⚠
protein kinase A regulatory subunit
— OG7
LmxM.12.0060 ⚠
ribonuclease mar1
— OG7
LmxM.27.2490 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LmxM.26.2080 ⚠
hypothetical protein, conserved
— OG7
LmxM.21.0340 ⚠
metallo-peptidase, Clan ME, Family M16, mitoc
— OG7
LmxM.13.0870 ⚠
metallo-peptidase, Clan ME, Family M16, mitoc
— OG7
LmxM.32.2610 ⚠
Mitochondrial-processing peptidase subunit al
— OG7
LmxM.10.0570 ⚠
zinc-binding dehydrogenase-like protein
— OG7
LmxM.03.0750
TatD related DNase, putative
— Both
LmxM.15.1200 ⚠
protein kinase, putative
— OG7
LmxM.33.2820 ⚠
regulatory subunit of protein kinase a-like p
— OG7
LmxM.31.3970 ⚠
cAMP response protein 1, putative
— OG7
LmxM.17.0350 ⚠
dihydrouridine synthase (Dus), putative
— OG7
LmxM.36.0470 ⚠
dihydrouridine synthase domain protein-like p
— OG7
LmxM.33.1140 ⚠
dihydrouridine synthase (Dus), putative
— OG7
LmxM.36.4450 ⚠
mitochondrial intermediate peptidase, putativ
— OG7
LmxM.01.0830 ⚠
hypothetical protein
— OG7
LmxM.02.0740 ⚠
metallo-peptidase, Clan MA(E), Family M3, pep
— OG7
LmxM.26.1570 ⚠
metallo-peptidase, Clan MA(E), Family M3, thi
— OG7
LmxM.32.2300
udp-glc 4'-epimerase, putative
— OG7
LmxM.36.3910
S-adenosylhomocysteine hydrolase
— OG7
LmxM.07.0805
N-acetylglucosamine-phosphate mutase, putativ
— OG7
LmxM.33.3550 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
LmxM.17.0250
cystathionine beta-synthase
— OG7
LmxM.34.3060 ⚠
ubiquitin-activating enzyme E1, putative
— Both
LmxM.30.2020 ⚠
succinyl-diaminopimelate desuccinylase-like p
— Both
LmxM.18.1080 ⚠
protein kinase A catalytic subunit 3
— OG6
LmxM.30.1930 ⚠
dihydrouridine synthase (Dus), putative
— Both
LmxM.34.4010 ⚠
protein kinase A catalytic subunit isoform 1
— OG6
LmxM.32.2130
hypothetical protein, conserved
— Both
LmxM.32.3050
tyrosyl-DNA phosphodiesterase-like protein
— Both
LmxM.20.0790 ⚠
tubulin-tyrosine ligase, putative
— Both
LmxM.23.0550 ⚠
ubiquitin-activating enzyme E1, putative
— Both
LmxM.29.3130
valyl-tRNA synthetase, putative
— Both
LmxM.03.0610
kinase-like protein
— Both
LmxM.15.1170
hypothetical protein, conserved
— Both
LmxM.07.0100
pitrilysin-like metalloprotease, metallo-pept
— Both
LmxM.08.0320 ⚠
mitochondrial associated ribonuclease, putati
— Both
LmxM.13.1240
Thiamin pyrophosphokinase, vitamin B1 binding
— Both
LmxM.10.0560 ⚠
zinc binding dehydrogenase-like protein
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.