LmxM.13.0870

metallo-peptidase, Clan ME, Family M16, mitochondrial processing peptidase alpha subunit, putative
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_146937 OG7: OG7_0001887 76 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 76 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.18.1040 ⚠
putative 5-oxoprolinase, putative
— OG7
LmxM.26.0580 ⚠
Protein of unknown function (DUF525), putativ
— OG7
LmxM.15.1200 ⚠
protein kinase, putative
— OG7
LmxM.34.2300 ⚠
hypothetical protein, conserved
— OG7
LmxM.34.3070 ⚠
hypothetical protein, conserved
— OG7
LmxM.33.1400 ⚠
d-isomer specific 2-hydroxyacid dehydrogenase
— OG7
LmxM.25.1730 ⚠
hypothetical protein, conserved
— OG7
LmxM.33.4280 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LmxM.13.0160 ⚠
protein kinase A regulatory subunit
— OG7
LmxM.18.0220 ⚠
RNA-binding protein 29, putative
— OG7
LmxM.33.3550 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
LmxM.36.1400 ⚠
The ARF-like 2 binding protein BART, putative
— OG7
LmxM.36.4450 ⚠
mitochondrial intermediate peptidase, putativ
— OG7
LmxM.28.0450 ⚠
DIS3-like exonuclease, putative
— OG7
LmxM.05.0970 ⚠
mercaptopyruvate sulfurtransferase
— OG7
LmxM.26.1570 ⚠
metallo-peptidase, Clan MA(E), Family M3, thi
— OG7
LmxM.04.0520 ⚠
huntingtin interacting protein (HIP), putativ
— OG7
LmxM.13.0550 ⚠
Uncharacterized ACR, COG1678, putative
— OG7
LmxM.28.0330 ⚠
rrp44p homologue, putative
— OG7
LmxM.33.1415 ⚠
d-isomer specific 2-hydroxyacid dehydrogenase
— OG7
LmxM.21.0150 ⚠
serine/threonine-protein kinase-like protein
— OG7
LmxM.08_29.2020 ⚠
5'-AMP-activated protein kinase catalytic sub
— OG7
LmxM.36.0900 ⚠
SNF1-related protein kinases, putative (fragm
— OG7
LmxM.28.2000 ⚠
phosphorylase kinase-like protein
— OG7
LmxM.09.1310 ⚠
PPPDE putative peptidase domain containing pr
— OG7
LmxM.07.0900 ⚠
protein kinase, putative, serine/threonine ki
— OG7
LmxM.31.1330 ⚠
PPPDE putative peptidase domain containing pr
— OG7
LmxM.18.0640 ⚠
serine/threonine kinase-like protein, putativ
— OG7
LmxM.32.1710 ⚠
protein kinase, putative
— OG7
LmxM.36.2360 ⚠
tyrosine aminotransferase, putative
— OG7
LmxM.34.2670 ⚠
ankyrin repeat protein, putative
— OG7
LmxM.11.0390 ⚠
hypothetical protein, conserved
— OG7
LmxM.24.0190 ⚠
hypothetical protein, conserved
— OG7
LmxM.33.2820 ⚠
regulatory subunit of protein kinase a-like p
— OG7
LmxM.04.0330 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LmxM.26.2240 ⚠
kynureninase, putative
— OG7
LmxM.07.0805 ⚠
N-acetylglucosamine-phosphate mutase, putativ
— OG7
LmxM.01.0830 ⚠
hypothetical protein
— OG7
LmxM.29.2490 ⚠
heat shock 70-related protein 1, mitochondria
— OG7
LmxM.03.0480 ⚠
Ankyrin repeats (3 copies)/DHHC palmitoyltran
— OG7
LmxM.31.3970 ⚠
cAMP response protein 1, putative
— OG7
LmxM.11.0700 ⚠
anion-transporting ATPase-like protein
— OG7
LmxM.31.0890 ⚠
ethanolamine-phosphate cytidylyltransferase
— OG7
LmxM.34.5310 ⚠
GTP-binding protein, putative
— OG7
LmxM.07.0100 ⚠
pitrilysin-like metalloprotease, metallo-pept
— OG7
LmxM.33.4120 ⚠
Alpha/beta hydrolase family, putative
— OG7
LmxM.29.2470 ⚠
heat shock 70-related protein 1, mitochondria
— OG7
LmxM.29.2460 ⚠
heat shock 70-related protein 1, mitochondria
— OG7
LmxM.36.6350 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LmxM.30.3090 ⚠
metallo-peptidase, Clan ME, Family M16, pepti
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.