LmxM.05.0330

DNA replication licensing factor, putative, minichromosome maintenance protein-like protein
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_104142 OG7: OG7_0001163 108 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 108 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.28.2385 ⚠
DNA replication licensing factor, putative
— +18 more Both
LmxM.24.0910 ⚠
minchromosome maintenance (MCM) complex subun
— +18 more Both
LmxM.31.2960 ⚠
minichromosome maintenance (MCM) complex subu
— +18 more Both
LmxM.09.0250 ⚠
DNA replication licensing factor MCM4
— +18 more Both
LmxM.34.4910 ⚠
DNA replication factor, putative
— +17 more OG7
LmxM.32.2700 ⚠
minichromosome maintenance (MCM) complex subu
— +17 more OG7
LmxM.28.0850 ⚠
minichromosome maintenance (MCM) complex subu
— +17 more OG7
LmxM.36.2410 ⚠
Cullin protein neddylation domain containing
— OG7
LmxM.28.1980 ⚠
hypothetical protein, conserved
— OG7
LmxM.36.2790 ⚠
Flagellar Member 1
— OG7
LmxM.29.0250 ⚠
ubiquitin hydrolase, putative
— OG7
LmxM.36.6770 ⚠
beta adaptin, putative
— OG7
LmxM.08_29.1900 ⚠
hypothetical protein, conserved
— OG7
LmxM.36.3530partial ⚠
polyubiquitin, putative
— OG7
LmxM.31.0140 ⚠
Flagellum attachment zone protein 9
— OG7
LmxM.11.0260 ⚠
hypothetical protein, conserved
— OG7
LmxM.25.0940 ⚠
hypothetical protein, conserved
— OG7
LmxM.22.1630 ⚠
ccr4-not transcription complex subunit
— OG7
LmxM.27.2490 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LmxM.11.0400 ⚠
tubulin-tyrsoine ligase-like protein
— OG7
LmxM.20.0790 ⚠
tubulin-tyrosine ligase, putative
— OG7
LmxM.34.4930 ⚠
tubulin tyrosine ligase, putative
— OG7
LmxM.18.0370 ⚠
tubulin tyrosine ligase protein, putative
— OG7
LmxM.08_29.0260 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LmxM.31.2930 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LmxM.29.2280 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LmxM.25.1300 ⚠
PRP38 family, putative
— OG7
LmxM.16.0380 ⚠
tubulin tyrosine ligase, putative
— OG7
LmxM.11.1300 ⚠
hypothetical protein, conserved
— OG7
LmxM.36.3060 ⚠
cullin-like protein
— OG7
LmxM.16.1220 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LmxM.25.1280 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LmxM.16.0660 ⚠
hypothetical protein, conserved
— OG7
LmxM.07.0550 ⚠
cysteine peptidase B (CPB), putative
— OG7
LmxM.11.0470 ⚠
pumilio-repeat, RNA-binding protein, putative
— OG7
LmxM.04.0550 ⚠
Intraflagellar transport protein 139, putativ
— OG7
LmxM.25.1490 ⚠
Rab3 GTPase-activating protein catalytic subu
— OG7
LmxM.26.0600 ⚠
hypothetical protein, conserved
— OG7
LmxM.14.0570 ⚠
WD domain, G-beta repeat, putative
— OG7
LmxM.09.0950 ⚠
O-phosphoseryl-tRNA(Sec) selenium transferase
— OG7
LmxM.04.0120 ⚠
exosome complex exonuclease RRP40, putative
— OG7
LmxM.15.1510 ⚠
hypothetical protein, conserved
— OG7
LmxM.30.1660 ⚠
GINS complex subunit Psf3, putative
— OG7
LmxM.08_29.2260 ⚠
DNA replication complex GINS protein SLD5, pu
— +2 more OG7
LmxM.11.0370 ⚠
hypothetical protein, conserved
— OG7
LmxM.24.2100 ⚠
hypothetical protein, conserved
— OG7
LmxM.18.0830 ⚠
Periodic tryptophan protein 2 homolog, putati
— OG7
LmxM.30.2610 ⚠
RNA polymerase ii largest subunit
— OG7
LmxM.32.2780 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LmxM.36.1720 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.