LmxM.07.0550

cysteine peptidase B (CPB), putative
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_478677 OG7: OG7_0293510 196 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 196 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.26.1260 ⚠
hypothetical protein, unknown function
— OG7
LmxM.15.0560
hypothetical protein, conserved
— Both
LmxM.14.0750
hypothetical protein, conserved
— Both
LmxM.08.0110
hypothetical protein, unknown function
— Both
LmxM.27.0820
parallel beta-helix repeat, putative
— Both
LmxM.19.1560 ⚠
inosine-5'-monophosphate dehydrogenase
— Both
LmxM.09.1180 ⚠
hypothetical protein, conserved
— Both
LmxM.08.0910
Beta-lactamase superfamily domain containing
— Both
LmxM.18.1210 ⚠
bifunctional aminoacyl-tRNA synthetase, putat
— Both
LmxM.32.2590
hypothetical protein, conserved
— Both
LmxM.34.3200
RNA-binding protein, putative
— Both
LmxM.28.0850 ⚠
minichromosome maintenance (MCM) complex subu
— Both
LmxM.19.0950
hypothetical protein, conserved
— Both
LmxM.11.0260
hypothetical protein, conserved
— Both
LmxM.14.0570
WD domain, G-beta repeat, putative
— Both
LmxM.02.0310
paraflagellar rod component, putative
— Both
LmxM.04.0350
hypothetical protein
— Both
LmxM.06.0190
hypothetical protein, conserved
— Both
LmxM.01.0430 ⚠
Ring finger domain/Zn-finger in ubiquitin-hyd
— Both
LmxM.33.3280 ⚠
Zn-finger in ubiquitin-hydrolases and other p
— OG7
LmxM.36.3000 ⚠
ATP-dependent RNA helicase, putative
— OG7
LmxM.20.0010 ⚠
DNA-directed RNA polymerase III, putative
— OG7
LmxM.36.6320 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
LmxM.34.3500 ⚠
zinc finger protein, putative
— OG7
LmxM.09.0891 ⚠
polyubiquitin, putative
— OG7
LmxM.24.0910 ⚠
minchromosome maintenance (MCM) complex subun
— OG7
LmxM.10.0195 ⚠
hypothetical protein, conserved
— OG7
LmxM.30.0310 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
LmxM.08_29.1830 ⚠
dihydrolipoamide dehydrogenase, putative
— OG7
LmxM.28.2110 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LmxM.24.2290 ⚠
cullin-like protein-like protein
— OG7
LmxM.17.0930 ⚠
formin, putative
— OG7
LmxM.30.0160 ⚠
DNA-directed RNA polymerase II subunit 2, put
— OG7
LmxM.24.1660 ⚠
SpoU rRNA Methylase family, putative
— OG7
LmxM.34.4930 ⚠
tubulin tyrosine ligase, putative
— OG7
LmxM.08_29.0600 ⚠
hypothetical protein, conserved
— OG7
LmxM.18.0370 ⚠
tubulin tyrosine ligase protein, putative
— OG7
LmxM.30.2610 ⚠
RNA polymerase ii largest subunit
— OG7
LmxM.36.4560 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmxM.31.1550 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmxM.10.0120 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmxM.31.2960 ⚠
minichromosome maintenance (MCM) complex subu
— OG7
LmxM.23.1570 ⚠
neutral sphingomyelinase activation associate
— OG7
LmxM.02.0120 ⚠
phosphatidylinositol 3-kinase-like protein
— OG7
LmxM.33.0360 ⚠
DNA-directed RNA polymerase III subunit C1, p
— OG7
LmxM.30.2650 ⚠
acetoin dehydrogenase e3 component-like prote
— OG7
LmxM.36.2940 ⚠
phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LmxM.29.0460 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmxM.34.0950 ⚠
cell cycle sequence binding phosphoprotein (R
— OG7
LmxM.36.7000 ⚠
PSP1 C-terminal conserved region, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.