LmxM.19.1560

inosine-5'-monophosphate dehydrogenase
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_100534 OG7: OG7_0002926 84 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 84 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.16.0590 ⚠
carbamoyl-phosphate synthase, putative
— Both
LmxM.10.0195 ⚠
hypothetical protein, conserved
— OG7
LmxM.27.0830 ⚠
hypothetical protein, conserved
— OG6
LmxM.18.1040 ⚠
putative 5-oxoprolinase, putative
— Both
LmxM.03.0900 ⚠
peter pan protein, putative
— OG6
LmxM.08.0410 ⚠
WD domain, G-beta repeat, putative
— Both
LmxM.31.0750 ⚠
nuclear RNA binding domain
— OG6
LmxM.02.0310 ⚠
paraflagellar rod component, putative
— Both
LmxM.27.1060 ⚠
cysteine desulfurase, putative
— OG6
LmxM.31.2840 ⚠
prefoldin subunit, putative
— Both
LmxM.11.0890 ⚠
hypothetical protein, conserved
— Both
LmxM.30.0310 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
LmxM.34.1090 ⚠
Nucleolar protein 111, putative
— OG6
LmxM.34.1270 ⚠
hypothetical protein, conserved
— OG6
LmxM.08_29.1830 ⚠
dihydrolipoamide dehydrogenase, putative
— Both
LmxM.29.0620 ⚠
ribosome biogenesis regulatory protein (RRS1)
— OG6
LmxM.16.1390 ⚠
EMG1/NEP1 methyltransferase, putative
— OG6
LmxM.34.0050 ⚠
2-oxoisovalerate dehydrogenase beta subunit,
— Both
LmxM.26.0010 ⚠
brix domain containing-like protein
— OG6
LmxM.25.1180 ⚠
ATP synthase subunit beta, mitochondrial, put
— Both
LmxM.11.0590 ⚠
3-methylcrotonoyl-CoA carboxylase beta subuni
— Both
LmxM.06.0810
hypothetical protein, unknown function
— OG7
LmxM.32.2170
hypothetical protein, conserved
— OG7
LmxM.36.3000 ⚠
ATP-dependent RNA helicase, putative
— OG7
LmxM.26.1420 ⚠
FYVE zinc finger, putative
— OG7
LmxM.14.1170 ⚠
hypothetical protein, conserved
— OG7
LmxM.19.0980 ⚠
FYVE zinc finger, putative
— OG7
LmxM.26.1260 ⚠
hypothetical protein, unknown function
— OG7
LmxM.34.3500 ⚠
zinc finger protein, putative
— OG7
LmxM.34.4260 ⚠
hypothetical protein, conserved
— OG7
LmxM.30.2640 ⚠
2-oxoglutarate dehydrogenase, e3 component, l
— OG7
LmxM.34.4750 ⚠
glyceraldehyde-3-phosphate dehydrogenase-like
— OG7
LmxM.30.2650 ⚠
acetoin dehydrogenase e3 component-like prote
— Both
LmxM.09.1170 ⚠
hypothetical protein, conserved
— OG7
LmxM.09.1180 ⚠
hypothetical protein, conserved
— OG7
LmxM.32.2570 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
LmxM.30.0360 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
LmxM.21.0895 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmxM.33.4030 ⚠
geranylgeranyltransferase, putative
— OG7
LmxM.29.0460 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmxM.08_29.0600 ⚠
hypothetical protein, conserved
— OG7
LmxM.32.2960 ⚠
hypothetical protein, conserved
— OG7
LmxM.30.0300 ⚠
CRAL/TRIO domain containing protein, putative
— Both
LmxM.30.1480 ⚠
hypothetical protein, unknown function
— Both
LmxM.26.0840 ⚠
hypothetical protein, conserved
— Both
LmxM.26.1470 ⚠
farnesyltransferase beta subunit
— Both
LmxM.36.1380 ⚠
hypothetical protein, conserved
— Both
LmxM.32.2740 ⚠
translation initiation factor IF-2, putative
— Both
LmxM.08_29.2360 ⚠
aspartyl aminopeptidase, putative
— Both
LmxM.08_29.1700 ⚠
MORN repeat, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.