LmxM.10.0195

hypothetical protein, conserved
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_105476 OG7: OG7_0010325 82 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 82 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.24.0490 ⚠
Leucine Rich repeats (2 copies)/Leucine rich
— OG7
LmxM.22.0060 ⚠
transcription factor-like protein
— OG7
LmxM.10.0690 ⚠
hypothetical protein, conserved
— OG7
LmxM.21.0875 ⚠
hypothetical protein, conserved
— OG7
LmxM.24.0650 ⚠
PPPDE putative peptidase domain containing pr
— OG7
LmxM.09.1300 ⚠
PPPDE putative peptidase domain containing pr
— OG7
LmxM.31.1330 ⚠
PPPDE putative peptidase domain containing pr
— OG7
LmxM.09.1310 ⚠
PPPDE putative peptidase domain containing pr
— OG7
LmxM.24.0010 ⚠
pyruvate dehydrogenase (lipoamide) kinase, pu
— OG7
LmxM.33.3900 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LmxM.20.0280 ⚠
developmentally regulated phosphoprotein-like
— OG7
LmxM.08_29.0600 ⚠
hypothetical protein, conserved
— OG7
LmxM.21.0180 ⚠
CHAT domain containing protein, putative
— OG7
LmxM.18.1040 ⚠
putative 5-oxoprolinase, putative
— OG7
LmxM.24.2020 ⚠
tubulin folding cofactor D, putative
— OG7
LmxM.02.0660 ⚠
Nop14-like family, putative
— OG7
LmxM.21.1670 ⚠
hypothetical protein, conserved
— OG7
LmxM.18.1220 ⚠
prolyl-tRNA synthetase, putative,bifunctional
— OG7
LmxM.18.1210 ⚠
bifunctional aminoacyl-tRNA synthetase, putat
— OG7
LmxM.02.0140 ⚠
Ankyrin repeats (3 copies)/Zinc finger, C3HC4
— OG7
LmxM.29.0910 ⚠
HECT E3 ligase, putative
— OG7
LmxM.08.0410 ⚠
WD domain, G-beta repeat, putative
— OG7
LmxM.07.0550 ⚠
cysteine peptidase B (CPB), putative
— OG7
LmxM.27.1350 ⚠
hypothetical protein, unknown function
— OG7
LmxM.23.1630 ⚠
hypothetical protein, conserved
— OG7
LmxM.34.2340 ⚠
ribonuclease, putative
— OG7
LmxM.36.6350 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LmxM.09.1100 ⚠
hypothetical protein, conserved
— OG7
LmxM.15.0430 ⚠
hypothetical protein, conserved
— OG7
LmxM.12.0250 ⚠
cysteinyl-tRNA synthetase, putative
— OG7
LmxM.16.1150 ⚠
hypothetical protein, conserved
— OG7
LmxM.29.1090 ⚠
WW domain containing protein, putative
— OG7
LmxM.03.0690 ⚠
DEAD/DEAH box helicase, putative
— OG7
LmxM.36.3000 ⚠
ATP-dependent RNA helicase, putative
— OG7
LmxM.04.0570 ⚠
DENN (AEX-3) domain containing protein, putat
— OG7
LmxM.19.1040 ⚠
phenylalanyl-tRNA synthetase, putative
— OG7
LmxM.28.1910 ⚠
p21-C-terminal region-binding protein, putati
— OG7
LmxM.07.0940 ⚠
Domain of unknown function (DUF3437), putativ
— OG7
LmxM.02.0310 ⚠
paraflagellar rod component, putative
— OG7
LmxM.21.0470 ⚠
vacuolar sorting-associated-like protein
— OG7
LmxM.11.0920 ⚠
Short C-terminal domain/PUB domain containing
— OG7
LmxM.29.0560 ⚠
hypothetical protein, conserved
— OG7
LmxM.36.1380 ⚠
hypothetical protein, conserved
— OG7
LmxM.32.2740 ⚠
translation initiation factor IF-2, putative
— OG7
LmxM.08_29.2360 ⚠
aspartyl aminopeptidase, putative
— OG7
LmxM.14.1170 ⚠
hypothetical protein, conserved
— OG7
LmxM.29.0460 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmxM.19.0980 ⚠
FYVE zinc finger, putative
— OG7
LmxM.26.1260 ⚠
hypothetical protein, unknown function
— OG7
LmxM.34.3200 ⚠
RNA-binding protein, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.