LmxM.11.0260

hypothetical protein, conserved
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_147362 OG7: OG7_0037845 154 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 154 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.31.3170
NADH dehydrogenase subunit NI8M, putative
— Both
LmxM.36.2410 ⚠
Cullin protein neddylation domain containing
— OG7
LmxM.28.0850 ⚠
minichromosome maintenance (MCM) complex subu
— Both
LmxM.19.0950
hypothetical protein, conserved
— Both
LmxM.14.0570
WD domain, G-beta repeat, putative
— Both
LmxM.34.2270
ATP-dependent RNA helicase-like protein
— OG6
LmxM.04.0940
hypothetical protein
— Both
LmxM.10.0820
hypothetical protein, conserved
— Both
LmxM.04.0290 ⚠
Alcohol dehydrogenase GroES-like domain conta
— Both
LmxM.05.0980
NADH-ubiquinone oxidoreductase, mitochondrial
— Both
LmxM.27.1880
hypothetical protein, conserved
— Both
LmxM.08_29.0690
NADH-ubiquinone oxidoreductase complex I subu
— Both
LmxM.29.0030
hypothetical protein, conserved
— Both
LmxM.34.1980
hypothetical protein, conserved
— Both
LmxM.28.2030
NADH dehydrogenase subunit NB6M, putative
— Both
LmxM.29.0580
AMP-binding enzyme, putative
— Both
LmxM.27.0290
acyl carrier protein, mitochondrial, putative
— Both
LmxM.26.2290
hypothetical protein, conserved
— Both
LmxM.05.0570
hypothetical protein, conserved
— Both
LmxM.17.0270
NADH-ubiquinone oxidoreductase, mitochondrial
— Both
LmxM.05.0520 ⚠
nuclear receptor binding factor-like protein
— Both
LmxM.20.0010 ⚠
DNA-directed RNA polymerase III, putative
— OG7
LmxM.36.6320 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
LmxM.09.0891 ⚠
polyubiquitin, putative
— OG7
LmxM.24.0910 ⚠
minchromosome maintenance (MCM) complex subun
— OG7
LmxM.08_29.1830 ⚠
dihydrolipoamide dehydrogenase, putative
— OG7
LmxM.28.2110 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LmxM.24.2290 ⚠
cullin-like protein-like protein
— OG7
LmxM.17.0930 ⚠
formin, putative
— OG7
LmxM.30.0160 ⚠
DNA-directed RNA polymerase II subunit 2, put
— OG7
LmxM.24.1660 ⚠
SpoU rRNA Methylase family, putative
— OG7
LmxM.34.4930 ⚠
tubulin tyrosine ligase, putative
— OG7
LmxM.18.0370 ⚠
tubulin tyrosine ligase protein, putative
— OG7
LmxM.30.2610 ⚠
RNA polymerase ii largest subunit
— OG7
LmxM.31.2960 ⚠
minichromosome maintenance (MCM) complex subu
— OG7
LmxM.23.1570 ⚠
neutral sphingomyelinase activation associate
— OG7
LmxM.02.0120 ⚠
phosphatidylinositol 3-kinase-like protein
— OG7
LmxM.33.0360 ⚠
DNA-directed RNA polymerase III subunit C1, p
— OG7
LmxM.30.2650 ⚠
acetoin dehydrogenase e3 component-like prote
— OG7
LmxM.36.2940 ⚠
phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LmxM.36.6770 ⚠
beta adaptin, putative
— OG7
LmxM.27.1260 ⚠
T-complex protein 1, beta subunit, putative
— OG7
LmxM.36.6910 ⚠
T-complex protein 1, theta subunit, putative
— OG7
LmxM.05.0330 ⚠
DNA replication licensing factor, putative, m
— OG7
LmxM.36.3530partial ⚠
polyubiquitin, putative
— OG7
LmxM.36.1720 ⚠
hypothetical protein, conserved
— OG7
LmxM.16.1220 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LmxM.20.0790 ⚠
tubulin-tyrosine ligase, putative
— OG7
LmxM.34.3860 ⚠
T-complex protein 1, eta subunit, putative
— OG7
LmxM.09.0250 ⚠
DNA replication licensing factor MCM4
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.