LmxM.36.2940

phosphatidylinositol 3- and 4-kinase, putative
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_196703 OG7: OG7_0001934 331 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 331 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.30.2640 ⚠
2-oxoglutarate dehydrogenase, e3 component, l
— OG7
LmxM.30.2650 ⚠
acetoin dehydrogenase e3 component-like prote
— OG7
LmxM.08_29.1830 ⚠
dihydrolipoamide dehydrogenase, putative
— OG7
LmxM.36.5240 ⚠
glycosyl hydrolase, putative
— Both
LmxM.32.1490 ⚠
hypothetical protein, conserved
— OG7
LmxM.31.2850 ⚠
CS domain/TPR repeat/Tetratricopeptide repeat
— OG7
LmxM.25.1300 ⚠
PRP38 family, putative
— OG7
LmxM.16.0660 ⚠
hypothetical protein, conserved
— OG7
LmxM.18.0570 ⚠
hypothetical protein, conserved
— OG7
LmxM.24.0840 ⚠
dynein light chain p28, axonemal, putative
— OG7
LmxM.26.1120 ⚠
axonemal dynein light chain, putative
— OG7
LmxM.32.1180 ⚠
Axonemal inner arm dynein light chain, putati
— OG7
LmxM.19.0160 ⚠
metallo-peptidase, Clan MG, Family M24
— OG7
LmxM.21.1020 ⚠
dynein arm light chain, putative
— OG7
LmxM.13.0680 ⚠
Metallopeptidase family M24, putative
— OG7
LmxM.23.1380 ⚠
DNA polymerase theta (helicase domain only),
— OG7
LmxM.31.1400 ⚠
ATP-dependent DNA DEAD/DEAH box helicase, put
— OG7
LmxM.36.1360 ⚠
adenylate kinase, putative
— OG7
LmxM.16.0020 ⚠
AAA domain containing protein, putative
— OG7
LmxM.23.1570 ⚠
neutral sphingomyelinase activation associate
— OG7
LmxM.31.1360 ⚠
RNA capping enzyme, cytoplasmic
— OG7
LmxM.04.0960 ⚠
adenylate kinase, putative
— OG7
LmxM.04.0890 ⚠
hypothetical protein, conserved
— OG7
LmxM.33.0360 ⚠
DNA-directed RNA polymerase III subunit C1, p
— OG7
LmxM.36.1720 ⚠
hypothetical protein, conserved
— OG7
LmxM.30.2610 ⚠
RNA polymerase ii largest subunit
— OG7
LmxM.32.2780 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LmxM.08.0420 ⚠
hypothetical protein,conserved
— OG7
LmxM.29.0490 ⚠
hypothetical protein, conserved
— OG7
LmxM.17.1320 ⚠
hypothetical protein, conserved
— OG7
LmxM.31.3170 ⚠
NADH dehydrogenase subunit NI8M, putative
— OG7
LmxM.30.0230 ⚠
hypothetical protein, conserved
— OG7
LmxM.24.2100 ⚠
hypothetical protein, conserved
— OG7
LmxM.36.2410 ⚠
Cullin protein neddylation domain containing
— OG7
LmxM.24.2290 ⚠
cullin-like protein-like protein
— OG7
LmxM.28.2110 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LmxM.16.1220 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LmxM.36.3060 ⚠
cullin-like protein
— OG7
LmxM.21.1050 ⚠
60S ribosomal protein L9, putative
— OG7
LmxM.29.3340 ⚠
60S ribosomal protein L9, putative
— OG7
LmxM.04.0500 ⚠
Nucleotidyltransferase domain containing prot
— OG7
LmxM.36.3991 ⚠
hypothetical protein
— OG7
LmxM.07.0700 ⚠
topoisomerase-related function protein-like p
— OG7
LmxM.26.0490 ⚠
DNA polymerase sigma-like protein
— OG7
LmxM.14.0930 ⚠
immunodominant antigen, putative, tc40 antige
— OG7
LmxM.11.0260 ⚠
hypothetical protein, conserved
— OG7
LmxM.25.0940 ⚠
hypothetical protein, conserved
— OG7
LmxM.05.0190 ⚠
Fip1 motif/Zinc finger C-x8-C-x5-C-x3-H type
— OG7
LmxM.20.1480 ⚠
Myotubularin-related protein, putative
— OG7
LmxM.29.3650 ⚠
ribosomal protein L15, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.