LmxM.08.0910

Beta-lactamase superfamily domain containing protein, putative
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_151473 OG7: OG7_0003196 89 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 89 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.33.1540
kinesin, putative
— OG6
LmxM.31.1550 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmxM.36.4560 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmxM.27.0550 ⚠
replication factor C, subunit 4, putative
— OG7
LmxM.15.1180
hypothetical protein, conserved
— OG7
LmxM.31.3150 ⚠
Flagellar Member 7
— OG7
LmxM.21.1110 ⚠
hypothetical protein, conserved
— OG7
LmxM.01.0430 ⚠
Ring finger domain/Zn-finger in ubiquitin-hyd
— Both
LmxM.06.0190
hypothetical protein, conserved
— Both
LmxM.04.0350
hypothetical protein
— Both
LmxM.01.0350
hypothetical protein, conserved
— Both
LmxM.09.1510
hypothetical protein, conserved
— Both
LmxM.10.0120 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmxM.25.1315 ⚠
DNA-directed RNA polymerase I subunit RPB10,
— Both
LmxM.19.0650
hypothetical protein, conserved
— Both
LmxM.09.1180 ⚠
hypothetical protein, conserved
— Both
LmxM.13.1120 ⚠
DNA-directed RNA polymerase ii 8.2 Kd polypep
— Both
LmxM.15.0560
hypothetical protein, conserved
— Both
LmxM.34.2180
hypothetical protein, conserved
— Both
LmxM.33.0300 ⚠
hypothetical protein, conserved
— Both
LmxM.34.1730
casein kinase II, putative
— OG6
LmxM.08_29.1460
hypothetical protein, conserved
— Both
LmxM.28.2490
hypothetical protein, conserved
— Both
LmxM.09.1170 ⚠
hypothetical protein, conserved
— OG7
LmxM.33.3280 ⚠
Zn-finger in ubiquitin-hydrolases and other p
— OG7
LmxM.33.4060 ⚠
ubiquitin hydrolase, putative
— OG7
LmxM.34.5000 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmxM.21.0400 ⚠
Peptidase C19, ubiquitin carboxyl-terminal hy
— OG7
LmxM.11.0140 ⚠
hypothetical protein, conserved
— OG7
LmxM.29.1200 ⚠
ubiquitin hydrolase, putative
— OG7
LmxM.17.0170 ⚠
WD domain, G-beta repeat, putative
— OG7
LmxM.31.0760 ⚠
cyclin 9, putative
— OG7
LmxM.36.7000 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmxM.08_29.1120 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmxM.15.0920
protein phosphatase 2A regulatory subunit, pu
— Both
LmxM.34.1740 ⚠
ubiquitin hydrolase, putative
— OG7
LmxM.36.6710 ⚠
replication factor C subunit 3, putative
— OG7
LmxM.24.0620 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LmxM.34.3250 ⚠
replication factor C, subunit 3, putative
— OG7
LmxM.33.2150 ⚠
eukaryotic translation initiation factor 2-al
— OG7
LmxM.21.0820 ⚠
Temperature dependent protein affecting M2 ds
— OG7
LmxM.17.0540 ⚠
ATPase family associated with various cellula
— OG7
LmxM.24.0990 ⚠
replication factor C, subunit 1, putative
— OG7
LmxM.34.0950 ⚠
cell cycle sequence binding phosphoprotein (R
— OG7
LmxM.29.2630 ⚠
replication factor C, subunit 2, putative
— OG7
LmxM.11.0060 ⚠
protein kinase, putative
— Both
LmxM.26.1650
hypothetical protein, conserved
— Both
LmxM.18.1450
Protein of unknown function (DUF3648), putati
— Both
LmxM.16.0730 ⚠
ubiquitin hydrolase, putative
— Both
LmxM.36.0970
hypothetical protein, conserved
— Both
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.