LmxM.21.0820

Temperature dependent protein affecting M2 dsRNA replication, putative
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_143822 OG7: OG7_0013037 101 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 101 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.10.1110 ⚠
PAB1-binding protein , putative
— OG7
LmxM.04.0120 ⚠
exosome complex exonuclease RRP40, putative
— Both
LmxM.15.0640 ⚠
Galactose oxidase, central domain/Kelch motif
— Both
LmxM.29.1120 ⚠
importin alpha, putative
— Both
LmxM.20.1360 ⚠
exosome-associated protein 1, putative
— Both
LmxM.29.1110
RNA-binding protein, putative
— OG6
LmxM.30.1210 ⚠
Protein of unknown function (DUF3638)/Protein
— Both
LmxM.26.0600 ⚠
hypothetical protein, conserved
— Both
LmxM.22.1590 ⚠
hypothetical protein, conserved
— Both
LmxM.36.4230 ⚠
paraflagellar rod component, putative
— Both
LmxM.36.5240 ⚠
glycosyl hydrolase, putative
— Both
LmxM.36.4145 ⚠
transcription factor S-II-like protein
— Both
LmxM.34.0290 ⚠
hypothetical protein, conserved
— Both
LmxM.07.0380 ⚠
RAVE protein 1 C terminal, putative
— Both
LmxM.07.0700 ⚠
topoisomerase-related function protein-like p
— Both
LmxM.03.0350 ⚠
hypothetical protein
— Both
LmxM.04.0030 ⚠
cAMP-specific phosphodiesterase, putative
— OG7
LmxM.29.2440 ⚠
hypothetical protein, conserved
— OG7
LmxM.16.0730 ⚠
ubiquitin hydrolase, putative
— OG7
LmxM.29.1200 ⚠
ubiquitin hydrolase, putative
— OG7
LmxM.21.0400 ⚠
Peptidase C19, ubiquitin carboxyl-terminal hy
— OG7
LmxM.24.0620 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LmxM.29.2730 ⚠
Stabilization of polarity axis, putative
— OG7
LmxM.32.1150 ⚠
pumilio protein, putative
— OG7
LmxM.20.1370 ⚠
RNA-binding regulatory protein, putative, pum
— OG7
LmxM.36.0050 ⚠
PUF1, putative
— OG7
LmxM.34.5290 ⚠
p21 antigen protein
— OG7
LmxM.20.1365 ⚠
hypothetical protein
— OG7
LmxM.12.0380 ⚠
pumillio protein 4, putative
— OG7
LmxM.06.0050 ⚠
hypothetical protein, conserved
— OG7
LmxM.28.2950 ⚠
hypothetical protein, conserved
— OG7
LmxM.20.1370a ⚠
hypothetical protein
— OG7
LmxM.18.1420 ⚠
pumilio protein, putative
— OG7
LmxM.21.1680 ⚠
RNA-binding regulatory protein (pumilio famil
— OG7
LmxM.22.0160 ⚠
hypothetical protein, conserved
— OG7
LmxM.22.0750 ⚠
hypothetical protein, conserved
— OG7
LmxM.08.0630 ⚠
hypothetical protein, unknown function
— OG7
LmxM.13.0690 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmxM.04.0350 ⚠
hypothetical protein
— OG7
LmxM.08_29.1120 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmxM.36.7000 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmxM.11.0140 ⚠
hypothetical protein, conserved
— OG7
LmxM.34.5000 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmxM.36.4560 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmxM.31.1550 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmxM.10.0120 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmxM.34.0950 ⚠
cell cycle sequence binding phosphoprotein (R
— OG7
LmxM.34.1740 ⚠
ubiquitin hydrolase, putative
— OG7
LmxM.15.1300 ⚠
ubiquitin hydrolase, putative
— OG7
LmxM.33.4060 ⚠
ubiquitin hydrolase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.