LmxM.04.0120

exosome complex exonuclease RRP40, putative
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_102463 OG7: OG7_0007513 174 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 174 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.02.0320 ⚠
ribosomal RNA processing protein 41B, putativ
— Both
LmxM.36.3020 ⚠
Ribosomal RNA processing protein 41A
— Both
LmxM.36.4895 ⚠
exosome-associated protein 4, putative
— OG7
LmxM.20.0010 ⚠
DNA-directed RNA polymerase III, putative
— OG7
LmxM.25.0620 ⚠
RNA polymerase I second largest subunit, puta
— Both
LmxM.22.1580 ⚠
exosome complex exonuclease RRP45 homolog, pu
— +2 more Both
LmxM.30.0160 ⚠
DNA-directed RNA polymerase II subunit 2, put
— OG7
LmxM.20.1360
exosome-associated protein 1, putative
— Both
LmxM.31.3460 ⚠
exosome-associated protein 2, putative
— +2 more Both
LmxM.23.1770
exosome component CSL4, putative
— Both
LmxM.14.0010
ribosomal RNA processing protein 4, putative,
— Both
LmxM.36.2410 ⚠
Cullin protein neddylation domain containing
— OG7
LmxM.28.2780 ⚠
heat-shock protein hsp70, putative
— Both
LmxM.25.1270
hypothetical protein, conserved
— Both
LmxM.25.1390 ⚠
hypothetical protein, conserved
— Both
LmxM.03.0350
hypothetical protein
— Both
LmxM.33.0840 ⚠
translation elongation factor 1-beta, putativ
— Both
LmxM.36.1430 ⚠
translation elongation factor 1-beta, putativ
— Both
LmxM.33.0820 ⚠
elongation factor 1-beta
— Both
LmxM.26.0480 ⚠
hypothetical protein, conserved
— OG7
LmxM.36.6320 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
LmxM.34.3500 ⚠
zinc finger protein, putative
— OG7
LmxM.09.0891 ⚠
polyubiquitin, putative
— OG7
LmxM.24.0910 ⚠
minchromosome maintenance (MCM) complex subun
— OG7
LmxM.31.1360 ⚠
RNA capping enzyme, cytoplasmic
— OG7
LmxM.31.1400 ⚠
ATP-dependent DNA DEAD/DEAH box helicase, put
— OG7
LmxM.26.0490 ⚠
DNA polymerase sigma-like protein
— OG7
LmxM.08_29.1830 ⚠
dihydrolipoamide dehydrogenase, putative
— OG7
LmxM.28.2110 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LmxM.24.2290 ⚠
cullin-like protein-like protein
— OG7
LmxM.16.0020 ⚠
AAA domain containing protein, putative
— OG7
LmxM.17.0930 ⚠
formin, putative
— OG7
LmxM.24.1660 ⚠
SpoU rRNA Methylase family, putative
— OG7
LmxM.34.4930 ⚠
tubulin tyrosine ligase, putative
— OG7
LmxM.32.1930 ⚠
phosphoribosyl transferase, putative, phospho
— OG7
LmxM.18.0370 ⚠
tubulin tyrosine ligase protein, putative
— OG7
LmxM.34.3510 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
LmxM.30.2610 ⚠
RNA polymerase ii largest subunit
— OG7
LmxM.21.1330partial ⚠
RecF/RecN/SMC N terminal domain/SMC proteins
— OG7
LmxM.05.0400 ⚠
structural maintenance of chromosome (SMC), p
— OG7
LmxM.31.2960 ⚠
minichromosome maintenance (MCM) complex subu
— OG7
LmxM.36.3991 ⚠
hypothetical protein
— OG7
LmxM.02.0120 ⚠
phosphatidylinositol 3-kinase-like protein
— OG7
LmxM.23.1570 ⚠
neutral sphingomyelinase activation associate
— OG7
LmxM.26.1260 ⚠
hypothetical protein, unknown function
— OG7
LmxM.19.0980 ⚠
FYVE zinc finger, putative
— OG7
LmxM.30.2650 ⚠
acetoin dehydrogenase e3 component-like prote
— OG7
LmxM.32.2700 ⚠
minichromosome maintenance (MCM) complex subu
— OG7
LmxM.36.5390 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
LmxM.16.1220 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.