LmxM.25.1315

DNA-directed RNA polymerase I subunit RPB10, putative
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_101548 OG7: OG7_0007040 60 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 60 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.36.4145 ⚠
transcription factor S-II-like protein
— OG7
LmxM.26.1650 ⚠
hypothetical protein, conserved
— Both
LmxM.36.2460 ⚠
hypothetical protein, conserved
— Both
LmxM.30.1710 ⚠
hypothetical protein, conserved
— Both
LmxM.36.5640 ⚠
Cyclin 12, L-type
— Both
LmxM.36.5760 ⚠
Rab3 GTPase-activating protein regulatory sub
— Both
LmxM.29.2730 ⚠
Stabilization of polarity axis, putative
— Both
LmxM.34.1620 ⚠
Concanavalin A-like lectin/glucanases superfa
— Both
LmxM.32.2560 ⚠
Unc104-like kinesin, putative
— OG6
LmxM.28.2490 ⚠
hypothetical protein, conserved
— Both
LmxM.08_29.1460 ⚠
hypothetical protein, conserved
— Both
LmxM.34.2180 ⚠
hypothetical protein, conserved
— Both
LmxM.33.1540 ⚠
kinesin, putative
— OG6
LmxM.27.0550 ⚠
replication factor C, subunit 4, putative
— OG7
LmxM.19.0420 ⚠
DNA-directed RNA polymerase III subunit C11,
— OG7
LmxM.29.2440 ⚠
hypothetical protein, conserved
— Both
LmxM.29.2630 ⚠
replication factor C, subunit 2, putative
— OG7
LmxM.24.0990 ⚠
replication factor C, subunit 1, putative
— OG7
LmxM.17.0540 ⚠
ATPase family associated with various cellula
— OG7
LmxM.34.3250 ⚠
replication factor C, subunit 3, putative
— OG7
LmxM.36.6710 ⚠
replication factor C subunit 3, putative
— OG7
LmxM.33.2150 ⚠
eukaryotic translation initiation factor 2-al
— OG7
LmxM.34.1740 ⚠
ubiquitin hydrolase, putative
— OG7
LmxM.33.4060 ⚠
ubiquitin hydrolase, putative
— OG7
LmxM.31.0760 ⚠
cyclin 9, putative
— OG7
LmxM.25.0620 ⚠
RNA polymerase I second largest subunit, puta
— OG7
LmxM.19.0660 ⚠
DNA-directed RNA polymerases I and III subuni
— OG7
LmxM.18.0790 ⚠
DNA-directed RNA polymerase I subunit RPB5z,
— OG7
LmxM.33.3280 ⚠
Zn-finger in ubiquitin-hydrolases and other p
— OG7
LmxM.09.1060 ⚠
DNA-directed RNA polymerase III subunit, puta
— OG7
LmxM.08.0910 ⚠
Beta-lactamase superfamily domain containing
— Both
LmxM.31.1280 ⚠
RNA polymerase-like protein, putative
— Both
LmxM.20.1100 ⚠
MORN repeat-containing protein
— Both
LmxM.28.2060 ⚠
DNA-directed RNA polymerase-like protein
— Both
LmxM.28.0120 ⚠
DNA-direcetd RNA polymerase II, subunit 9, pu
— Both
LmxM.18.0780 ⚠
DNA-directed RNA polymerases II, putative
— Both
LmxM.09.1510 ⚠
hypothetical protein, conserved
— Both
LmxM.25.0140 ⚠
hypothetical protein, conserved
— Both
LmxM.19.0650 ⚠
hypothetical protein, conserved
— Both
LmxM.08.0110 ⚠
hypothetical protein, unknown function
— Both
LmxM.28.0810 ⚠
RNA polymerase B subunit RPB8, putative
— Both
LmxM.15.1300 ⚠
ubiquitin hydrolase, putative
— Both
LmxM.21.1130 ⚠
hypothetical protein, conserved
— Both
LmxM.10.0330 ⚠
hypothetical protein, conserved
— Both
LmxM.20.1090 ⚠
hypothetical protein, conserved
— Both
LmxM.11.0060 ⚠
protein kinase, putative
— Both
LmxM.20.0490 ⚠
RNA polymerase subunit, putative
— Both
LmxM.20.0820 ⚠
hypothetical protein, conserved
— Both
LmxM.01.0350 ⚠
hypothetical protein, conserved
— Both
LmxM.33.0890 ⚠
DNA-directed RNA polymerase subunit, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.