LmxM.22.1630

ccr4-not transcription complex subunit
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_101138 OG7: OG7_0005422 149 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 149 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.21.0800
CCR4-NOT transcription complex subunit 1
— Both
LmxM.23.0020
hypothetical protein, conserved
— Both
LmxM.25.1840
General negative regulator of transcription s
— Both
LmxM.12.0350
CCR4-NOT transcription complex subunit 2, put
— Both
LmxM.33.4550
cell differentiation protein-like protein
— Both
LmxM.30.2650 ⚠
acetoin dehydrogenase e3 component-like prote
— OG7
LmxM.36.6100
CCR4-NOT transcription complex subunit 10, pu
— Both
LmxM.19.0680 ⚠
Flagellum attachment zone protein 7
— OG6
LmxM.16.1350 ⚠
DNA-directed rna polymerase I largest subunit
— Both
LmxM.19.0690 ⚠
Flagellum attachment zone protein 7
— OG6
LmxM.14.0570
WD domain, G-beta repeat, putative
— Both
LmxM.12.0610 ⚠
TPR repeat, putative
— Both
LmxM.22.1590
hypothetical protein, conserved
— Both
LmxM.29.2190
RNA-binding protein, putative
— OG6
LmxM.06.1160
hypothetical protein, conserved
— Both
LmxM.16.0380 ⚠
tubulin tyrosine ligase, putative
— Both
LmxM.09.1220
AAA family ATPase, putative
— Both
LmxM.05.1080a ⚠
Phosphatidylinositol 4-phosphate 5-kinase, pu
— OG7
LmxM.05.1080 ⚠
Phosphatidylinositol 4-phosphate 5-kinase, pu
— OG7
LmxM.33.2450 ⚠
Sec7 domain containing protein, putative
— OG7
LmxM.33.2520 ⚠
Guanine nucleotide exchange factor in Golgi t
— OG7
LmxM.16.1140 ⚠
WW domain containing protein, putative
— OG7
LmxM.34.5390 ⚠
HECT E3 ligase, putative
— OG7
LmxM.29.1090 ⚠
WW domain containing protein, putative
— OG7
LmxM.29.0910 ⚠
HECT E3 ligase, putative
— OG7
LmxM.05.0410 ⚠
TPR repeat, putative
— OG7
LmxM.29.3370
hypothetical protein, conserved
— OG7
LmxM.20.0010 ⚠
DNA-directed RNA polymerase III, putative
— OG7
LmxM.36.6320 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
LmxM.09.0891 ⚠
polyubiquitin, putative
— OG7
LmxM.24.0910 ⚠
minchromosome maintenance (MCM) complex subun
— OG7
LmxM.08_29.1830 ⚠
dihydrolipoamide dehydrogenase, putative
— OG7
LmxM.13.1470 ⚠
HECT E3 ligase, putative
— OG7
LmxM.28.2110 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LmxM.24.2290 ⚠
cullin-like protein-like protein
— OG7
LmxM.17.0930 ⚠
formin, putative
— OG7
LmxM.30.0160 ⚠
DNA-directed RNA polymerase II subunit 2, put
— OG7
LmxM.24.1660 ⚠
SpoU rRNA Methylase family, putative
— OG7
LmxM.31.2960 ⚠
minichromosome maintenance (MCM) complex subu
— OG7
LmxM.23.1570 ⚠
neutral sphingomyelinase activation associate
— OG7
LmxM.27.2490 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LmxM.18.0370 ⚠
tubulin tyrosine ligase protein, putative
— OG7
LmxM.34.4930 ⚠
tubulin tyrosine ligase, putative
— OG7
LmxM.20.0790 ⚠
tubulin-tyrosine ligase, putative
— OG7
LmxM.11.0400 ⚠
tubulin-tyrsoine ligase-like protein
— OG7
LmxM.36.3530partial ⚠
polyubiquitin, putative
— OG7
LmxM.09.0250 ⚠
DNA replication licensing factor MCM4
— OG7
LmxM.36.6770 ⚠
beta adaptin, putative
— OG7
LmxM.08_29.0260 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LmxM.05.0330 ⚠
DNA replication licensing factor, putative, m
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.