LmxM.33.2520

Guanine nucleotide exchange factor in Golgi transport N-terminal/Sec7 domain/Domain of unknown function (DUF1981), putative
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_154458 OG7: OG7_0001170 170 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 170 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.04.0690 ⚠
axonemal dynein light chain, putative
— OG7
LmxM.31.1460 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LmxM.24.1960 ⚠
hypothetical protein, conserved
— OG7
LmxM.34.2700 ⚠
hypothetical protein, conserved
— OG7
LmxM.36.1150 ⚠
endonuclease/exonuclease/phosphatase, putativ
— OG7
LmxM.21.1020 ⚠
dynein arm light chain, putative
— OG7
LmxM.13.0160 ⚠
protein kinase A regulatory subunit
— OG7
LmxM.33.0840 ⚠
translation elongation factor 1-beta, putativ
— OG7
LmxM.32.2780 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LmxM.31.1340 ⚠
cleavage and polyadenylation specificity fact
— OG7
LmxM.31.1470 ⚠
Microtubule-binding protein MIP-T3, putative
— OG7
LmxM.15.1200 ⚠
protein kinase, putative
— OG7
LmxM.19.0940 ⚠
CAP-Gly domain containing protein, putative
— OG7
LmxM.24.0820 ⚠
inositol polyphosphate phosphatase, putative
— OG7
LmxM.14.0930 ⚠
immunodominant antigen, putative, tc40 antige
— OG7
LmxM.12.0010 ⚠
translation initiation factor EIF-2b alpha su
— OG7
LmxM.36.1430 ⚠
translation elongation factor 1-beta, putativ
— OG7
LmxM.33.4310 ⚠
coatomer alpha subunit, putative
— OG7
LmxM.36.6340 ⚠
HECT E3 ligase, putative
— OG7
LmxM.29.0710 ⚠
CDC16, putative
— OG7
LmxM.21.0530 ⚠
hypothetical protein, conserved
— OG7
LmxM.34.4230 ⚠
hypothetical protein, conserved
— OG7
LmxM.11.0830 ⚠
hypothetical protein, conserved
— OG7
LmxM.10.1060 ⚠
hypothetical protein, conserved
— OG7
LmxM.12.0510 ⚠
WW domain containing protein, putative
— OG7
LmxM.16.1140 ⚠
WW domain containing protein, putative
— OG7
LmxM.36.1720 ⚠
hypothetical protein, conserved
— OG7
LmxM.30.3110 ⚠
Flagellum attachment zone protein 14
— OG7
LmxM.08.0010 ⚠
adaptor complex protein (AP) 3 delta subunit
— OG7
LmxM.33.2820 ⚠
regulatory subunit of protein kinase a-like p
— OG7
LmxM.19.1010 ⚠
WD domain, G-beta repeat, putative
— OG7
LmxM.17.0430 ⚠
Kinetochore interacting protein 5, putative
— OG7
LmxM.27.1210 ⚠
translation initiation factor eIF2B delta sub
— OG7
LmxM.33.0820 ⚠
elongation factor 1-beta
— OG7
LmxM.36.6980 ⚠
eukaryotic translation initiation factor 3 su
— OG7
LmxM.23.1640 ⚠
Galactose oxidase, central domain containing
— OG7
LmxM.10.0950 ⚠
translation initiation factor eif-2b beta sub
— OG7
LmxM.31.1130 ⚠
hypothetical protein, conserved
— OG7
LmxM.15.0700 ⚠
hypothetical protein, conserved
— OG7
LmxM.04.0740 ⚠
hypothetical protein, conserved
— OG7
LmxM.04.0530 ⚠
hypothetical protein
— OG7
LmxM.25.1610 ⚠
Eukaryotic translation initiation factor 3 su
— OG7
LmxM.25.1570 ⚠
ER-golgi trafficking TRAPP I complex 85 kDa s
— OG7
LmxM.24.0280 ⚠
Dynein intermediate chain 1, axonemal
— OG7
LmxM.34.4330 ⚠
pre-RNA processing PIH1/Nop17, putative
— OG7
LmxM.32.2630 ⚠
dynein intermediate chain, putative
— OG7
LmxM.08_29.0100 ⚠
hypothetical protein, conserved
— OG7
LmxM.14.1130 ⚠
hypothetical protein, conserved
— OG7
LmxM.24.1060 ⚠
AKAP7 2'5' RNA ligase-like domain containing
— OG7
LmxM.20.0930 ⚠
transmembrane protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.