LmxM.10.0950

translation initiation factor eif-2b beta subunit, putative, eIF-2B GDP-GTP exchange factor, putative
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_102470 OG7: OG7_0001817 73 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 73 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.31.1470 ⚠
Microtubule-binding protein MIP-T3, putative
— OG7
LmxM.19.1010 ⚠
WD domain, G-beta repeat, putative
— OG7
LmxM.33.2820 ⚠
regulatory subunit of protein kinase a-like p
— OG7
LmxM.08.0010 ⚠
adaptor complex protein (AP) 3 delta subunit
— OG7
LmxM.28.2580 ⚠
leucine-rich repeat protein, putative
— OG7
LmxM.21.0530 ⚠
hypothetical protein, conserved
— OG7
LmxM.36.6340 ⚠
HECT E3 ligase, putative
— OG7
LmxM.14.0930 ⚠
immunodominant antigen, putative, tc40 antige
— OG7
LmxM.19.0940 ⚠
CAP-Gly domain containing protein, putative
— OG7
LmxM.15.1200 ⚠
protein kinase, putative
— OG7
LmxM.10.1060 ⚠
hypothetical protein, conserved
— OG7
LmxM.13.0160 ⚠
protein kinase A regulatory subunit
— OG7
LmxM.21.1020 ⚠
dynein arm light chain, putative
— OG7
LmxM.31.0970 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG7
LmxM.24.1960 ⚠
hypothetical protein, conserved
— OG7
LmxM.31.1460 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LmxM.24.1970 ⚠
Nucleoporin NUP76
— OG7
LmxM.24.0840 ⚠
dynein light chain p28, axonemal, putative
— OG7
LmxM.13.0270 ⚠
hypothetical protein, conserved
— OG7
LmxM.04.0690 ⚠
axonemal dynein light chain, putative
— OG7
LmxM.04.0550 ⚠
Intraflagellar transport protein 139, putativ
— OG7
LmxM.11.0830 ⚠
hypothetical protein, conserved
— OG7
LmxM.17.1150 ⚠
5'-3' exoribonuclease B, putative
— OG7
LmxM.06.0260 ⚠
5'-3' exoribonuclease A, putative
— OG7
LmxM.36.1790 ⚠
5'-3' exoribonuclease D, putative
— OG7
LmxM.05.0920 ⚠
paraflagellar rod protein, putative
— OG7
LmxM.09.1220 ⚠
AAA family ATPase, putative
— OG7
LmxM.11.0590 ⚠
3-methylcrotonoyl-CoA carboxylase beta subuni
— OG7
LmxM.19.0100 ⚠
fibrillarin, putative
— OG7
LmxM.29.0910 ⚠
HECT E3 ligase, putative
— OG7
LmxM.29.1090 ⚠
WW domain containing protein, putative
— OG7
LmxM.07.0280 ⚠
HECT E3 ligase, putative
— OG7
LmxM.34.5390 ⚠
HECT E3 ligase, putative
— OG7
LmxM.16.1140 ⚠
WW domain containing protein, putative
— OG7
LmxM.07.0120 ⚠
Sec7 domain containing protein, putative
— OG7
LmxM.33.2520 ⚠
Guanine nucleotide exchange factor in Golgi t
— OG7
LmxM.33.2450 ⚠
Sec7 domain containing protein, putative
— OG7
LmxM.31.0310 ⚠
intraflagellar transport protein 140, putativ
— OG7
LmxM.29.0490 ⚠
hypothetical protein, conserved
— OG7
LmxM.21.0800 ⚠
CCR4-NOT transcription complex subunit 1
— OG7
LmxM.23.0900 ⚠
hypothetical protein, conserved
— OG7
LmxM.25.1840 ⚠
General negative regulator of transcription s
— OG7
LmxM.33.1510 ⚠
hypothetical protein, conserved
— OG7
LmxM.32.1490 ⚠
hypothetical protein, conserved
— OG7
LmxM.13.1470 ⚠
HECT E3 ligase, putative
— OG7
LmxM.32.0280 ⚠
hypothetical protein, conserved
— OG7
LmxM.34.3510 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
LmxM.14.0790 ⚠
hypothetical protein, conserved
— OG7
LmxM.03.0270 ⚠
FYVE zinc finger/Apolipoprotein A1/A4/E domai
— OG7
LmxM.31.3970 ⚠
cAMP response protein 1, putative
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.