LmxM.05.0920

paraflagellar rod protein, putative
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_134897 OG7: OG7_0037847 142 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 142 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.34.5390 ⚠
HECT E3 ligase, putative
— OG7
LmxM.14.0810
kinesin, putative
— OG6
LmxM.29.0490
hypothetical protein, conserved
— Both
LmxM.34.3960 ⚠
protein kinase A catalytic subunit isoform 2
— OG6
LmxM.36.1440
N-terminal region of Chorein, a TM vesicle-me
— Both
LmxM.29.0050
MATH domain containing protein, putative
— Both
LmxM.29.2210
endosomal trafficking protein RME-8, putative
— Both
LmxM.21.1330partial ⚠
RecF/RecN/SMC N terminal domain/SMC proteins
— Both
LmxM.25.0170 ⚠
cleavage and polyadenylation specificity fact
— Both
LmxM.12.0110 ⚠
hypothetical protein, conserved
— Both
LmxM.09.0800
kinetoplast-associated protein-like protein
— OG6
LmxM.07.0280 ⚠
HECT E3 ligase, putative
— Both
LmxM.07.0120 ⚠
Sec7 domain containing protein, putative
— Both
LmxM.01.0600
Rab-GTPase-TBC domain containing protein, put
— Both
LmxM.04.0550
Intraflagellar transport protein 139, putativ
— Both
LmxM.02.0120 ⚠
phosphatidylinositol 3-kinase-like protein
— Both
LmxM.05.0190
Fip1 motif/Zinc finger C-x8-C-x5-C-x3-H type
— Both
LmxM.25.0220
hypothetical protein, conserved
— Both
LmxM.14.0340
inositol polyphosphate kinase-like protein, p
— Both
LmxM.31.0470
hypothetical protein, conserved
— OG6
LmxM.26.2370
HECT E3 ligase, putative
— Both
LmxM.27.1630 ⚠
inner dynein arm I1 intermediate chain, axone
— Both
LmxM.04.0690
axonemal dynein light chain, putative
— Both
LmxM.03.0970 ⚠
MORN repeat, putative
— Both
LmxM.05.1080a ⚠
Phosphatidylinositol 4-phosphate 5-kinase, pu
— OG7
LmxM.05.1080 ⚠
Phosphatidylinositol 4-phosphate 5-kinase, pu
— OG7
LmxM.33.3940 ⚠
target of rapamycin kinase 3, putative
— OG7
LmxM.31.3970 ⚠
cAMP response protein 1, putative
— OG7
LmxM.03.0270 ⚠
FYVE zinc finger/Apolipoprotein A1/A4/E domai
— OG7
LmxM.13.1470 ⚠
HECT E3 ligase, putative
— OG7
LmxM.36.2600 ⚠
cyclin-e binding protein 1-like protein
— OG7
LmxM.03.0480 ⚠
Ankyrin repeats (3 copies)/DHHC palmitoyltran
— OG7
LmxM.32.0140 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LmxM.29.3260 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LmxM.33.1390 ⚠
N-terminal region of Chorein, a TM vesicle-me
— OG7
LmxM.20.1240 ⚠
Raptor N-terminal CASPase like domain contain
— OG7
LmxM.16.1140 ⚠
WW domain containing protein, putative
— OG7
LmxM.21.1020 ⚠
dynein arm light chain, putative
— OG7
LmxM.13.0160 ⚠
protein kinase A regulatory subunit
— OG7
LmxM.09.0990 ⚠
N-terminal region of Chorein, a TM vesicle-me
— OG7
LmxM.36.4060 ⚠
regulator of chromosome condensation 1-like p
— OG7
LmxM.33.4280 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LmxM.30.2720 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmxM.33.2450 ⚠
Sec7 domain containing protein, putative
— OG7
LmxM.33.2520 ⚠
Guanine nucleotide exchange factor in Golgi t
— OG7
LmxM.13.0440
mitogen-activated protein kinase kinase 2
— OG7
LmxM.10.0950 ⚠
translation initiation factor eif-2b beta sub
— OG7
LmxM.31.1060 ⚠
Dynein intermediate chain, axonemal
— OG7
LmxM.34.2670 ⚠
ankyrin repeat protein, putative
— OG7
LmxM.12.0700
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.