LmxM.26.1180

hypothetical protein, conserved
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_156939 OG7: OG7_0043894 81 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 81 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.33.2760
hypothetical protein, conserved
— +2 more Both
LmxM.21.0875
hypothetical protein, conserved
— Both
LmxM.26.0310 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
LmxM.34.5390 ⚠
HECT E3 ligase, putative
— OG7
LmxM.29.0730 ⚠
co-chaperone GrpE, putative
— OG7
LmxM.33.3960 ⚠
HECT E3 ligase, putative
— OG7
LmxM.19.1020 ⚠
tRNA pseudouridine synthase A-like protein
— OG7
LmxM.33.0310 ⚠
tRNA pseudouridine synthase, putative
— OG7
LmxM.26.0550 ⚠
galactofuranosyltransferase lpg1-like protein
— OG7
LmxM.25.0010 ⚠
beta galactofuranosyl transferase
— OG7
LmxM.26.0420 ⚠
pseudouridylate synthase-like protein
— OG7
LmxM.36.0150 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
LmxM.33.4030 ⚠
geranylgeranyltransferase, putative
— OG7
LmxM.33.4260
Unc104-like kinesin, putative
— OG6
LmxM.29.2320
SET domain containing protein, putative
— Both
LmxM.14.0130 ⚠
nucleoside hydrolase-like protein
— Both
LmxM.07.0760 ⚠
6-phosphofructo-2-kinase-like protein
— Both
LmxM.36.5170
vacuolar protein sorting-associated protein-l
— Both
LmxM.29.1550 ⚠
pseudouridine synthase A-like protein, putati
— Both
LmxM.03.0800 ⚠
6-phosphofructo-2-kinase 1
— Both
LmxM.18.1580 ⚠
nonspecific nucleoside hydrolase
— Both
LmxM.32.0550
hypothetical protein, conserved
— Both
LmxM.34.3250 ⚠
replication factor C, subunit 3, putative
— OG7
LmxM.36.1955 ⚠
TLD, putative
— OG7
LmxM.06.0940 ⚠
hypothetical protein, conserved
— OG7
LmxM.01.0160 ⚠
LSM domain containing protein, putative
— OG7
LmxM.25.1705 ⚠
LSM domain containing protein, putative
— OG7
LmxM.34.4460 ⚠
sm-f snRNP core complex protein, putative
— OG7
LmxM.29.1205 ⚠
small nuclear ribonucleoprotein polypeptide e
— OG7
LmxM.01.0710 ⚠
ubiquitin activating enzyme, putative
— OG7
LmxM.31.1070 ⚠
small nuclear ribonucleoprotein, putative
— OG7
LmxM.36.6710 ⚠
replication factor C subunit 3, putative
— OG7
LmxM.07.0280 ⚠
HECT E3 ligase, putative
— OG7
LmxM.20.1090 ⚠
hypothetical protein, conserved
— OG7
LmxM.17.0540 ⚠
ATPase family associated with various cellula
— OG7
LmxM.29.2630 ⚠
replication factor C, subunit 2, putative
— OG7
LmxM.27.0550 ⚠
replication factor C, subunit 4, putative
— OG7
LmxM.36.4370 ⚠
HECT E3 ligase, putative
— OG7
LmxM.16.1140 ⚠
WW domain containing protein, putative
— OG7
LmxM.34.2450 ⚠
HECT E3 ligase, putative
— OG7
LmxM.29.1090 ⚠
WW domain containing protein, putative
— OG7
LmxM.36.1860
Ribosomal protein S5, C-terminal domain conta
— Both
LmxM.32.0410
DNA mismatch repair protein MSH2, putative
— Both
LmxM.34.0920
hypothetical protein, conserved
— Both
LmxM.29.0560
hypothetical protein, conserved
— Both
LmxM.32.2260
glycosyl hydrolase-like protein
— Both
LmxM.08_29.2490
protein kinase, putative
— Both
LmxM.29.0910 ⚠
HECT E3 ligase, putative
— Both
LmxM.36.4920
hypothetical protein, conserved
— Both
LmxM.26.1470 ⚠
farnesyltransferase beta subunit
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.