LmxM.11.0930

hypothetical protein, conserved
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_156980 OG7: OG7_0050890 62 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 62 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.17.1140 ⚠
WW domain containing protein, putative
— OG7
LmxM.18.1210 ⚠
bifunctional aminoacyl-tRNA synthetase, putat
— Both
LmxM.30.0860
ras-like small GTPases, putative
— OG6
LmxM.07.0940
Domain of unknown function (DUF3437), putativ
— Both
LmxM.11.0920
Short C-terminal domain/PUB domain containing
— Both
LmxM.08.0410
WD domain, G-beta repeat, putative
— Both
LmxM.36.6430 ⚠
protein transport protein Sec23-like protein
— OG7
LmxM.36.3000 ⚠
ATP-dependent RNA helicase, putative
— OG7
LmxM.06.0940 ⚠
hypothetical protein, conserved
— OG7
LmxM.36.1955 ⚠
TLD, putative
— OG7
LmxM.27.1620 ⚠
Eukaryotic translation initiation factor 4E-1
— OG7
LmxM.27.0550 ⚠
replication factor C, subunit 4, putative
— OG7
LmxM.28.2390 ⚠
WW domain containing protein, putative
— OG7
LmxM.08_29.0600 ⚠
hypothetical protein, conserved
— OG7
LmxM.34.5390 ⚠
HECT E3 ligase, putative
— OG7
LmxM.29.2630 ⚠
replication factor C, subunit 2, putative
— OG7
LmxM.14.0460 ⚠
cystathionine beta-lyase-like protein
— Both
LmxM.07.0280 ⚠
HECT E3 ligase, putative
— OG7
LmxM.29.0460 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmxM.17.0540 ⚠
ATPase family associated with various cellula
— OG7
LmxM.29.1090 ⚠
WW domain containing protein, putative
— OG7
LmxM.36.4890 ⚠
hypothetical protein, conserved
— OG7
LmxM.20.1090 ⚠
hypothetical protein, conserved
— OG7
LmxM.31.0730 ⚠
Outer row dynein-assembly protein 7
— OG7
LmxM.29.0910 ⚠
HECT E3 ligase, putative
— OG7
LmxM.34.3250 ⚠
replication factor C, subunit 3, putative
— OG7
LmxM.21.0895 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmxM.36.6710 ⚠
replication factor C subunit 3, putative
— OG7
LmxM.19.1480 ⚠
Eukaryotic translation initiation factor 4E-2
— OG7
LmxM.28.2500 ⚠
Eukaryotic translation initiation factor 4E-3
— OG7
LmxM.15.0300 ⚠
Ecotin-like protein
— OG7
LmxM.12.0250
cysteinyl-tRNA synthetase, putative
— Both
LmxM.03.0450 ⚠
TLD domain protein, conserved
— Both
LmxM.09.1100
hypothetical protein, conserved
— Both
LmxM.03.0690 ⚠
DEAD/DEAH box helicase, putative
— Both
LmxM.06.0370
glutamine synthetase, putative
— Both
LmxM.29.0450 ⚠
Eukaryotic translation initiation factor 4E-4
— Both
LmxM.34.3230 ⚠
cystathione gamma lyase, putative
— Both
LmxM.34.4810
BRCA1 C Terminus (BRCT) domain containing pro
— Both
LmxM.22.0060 ⚠
transcription factor-like protein
— Both
LmxM.33.2340 ⚠
asparaginyl-tRNA synthetase, putative
— Both
LmxM.12.0510 ⚠
WW domain containing protein, putative
— Both
LmxM.24.2020
tubulin folding cofactor D, putative
— Both
LmxM.16.1140 ⚠
WW domain containing protein, putative
— Both
LmxM.15.0520 ⚠
ecotin, putative
— Both
LmxM.26.1220 ⚠
hypothetical protein, conserved
— Both
LmxM.23.0320
hypothetical protein, conserved
— Both
LmxM.10.0310 ⚠
protein transport protein SEC23, putative
— Both
LmxM.24.0990 ⚠
replication factor C, subunit 1, putative
— Both
LmxM.13.0620
hypothetical protein, conserved
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.