LmxM.14.0460

cystathionine beta-lyase-like protein
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_100353 OG7: OG7_0002476 59 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 59 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.34.5390 ⚠
HECT E3 ligase, putative
— OG7
LmxM.36.2850 ⚠
hypothetical protein, conserved
— Both
LmxM.19.1040 ⚠
phenylalanyl-tRNA synthetase, putative
— Both
LmxM.21.0180 ⚠
CHAT domain containing protein, putative
— Both
LmxM.17.0400 ⚠
Ring finger domain containing protein, putati
— Both
LmxM.16.1150 ⚠
hypothetical protein, conserved
— Both
LmxM.11.0930 ⚠
hypothetical protein, conserved
— Both
LmxM.36.3910 ⚠
S-adenosylhomocysteine hydrolase
— Both
LmxM.07.0940 ⚠
Domain of unknown function (DUF3437), putativ
— Both
LmxM.31.3040 ⚠
protein phosphatase 2A catalytic subunit, put
— OG6
LmxM.28.2670 ⚠
protein phosphatase 4 catalytic subunit, puta
— OG6
LmxM.36.1760 ⚠
aldehyde dehydrogenase, putative
— Both
LmxM.10.0195 ⚠
hypothetical protein, conserved
— OG7
LmxM.34.2340 ⚠
ribonuclease, putative
— OG7
LmxM.33.3900 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LmxM.36.6350 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
LmxM.31.1330 ⚠
PPPDE putative peptidase domain containing pr
— OG7
LmxM.07.0280 ⚠
HECT E3 ligase, putative
— OG7
LmxM.26.1260 ⚠
hypothetical protein, unknown function
— OG7
LmxM.19.0980 ⚠
FYVE zinc finger, putative
— OG7
LmxM.29.0460 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmxM.29.1090 ⚠
WW domain containing protein, putative
— OG7
LmxM.14.1170 ⚠
hypothetical protein, conserved
— OG7
LmxM.29.0910 ⚠
HECT E3 ligase, putative
— OG7
LmxM.26.1420 ⚠
FYVE zinc finger, putative
— OG7
LmxM.21.0895 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmxM.09.1310 ⚠
PPPDE putative peptidase domain containing pr
— OG7
LmxM.20.0280 ⚠
developmentally regulated phosphoprotein-like
— OG7
LmxM.34.4260 ⚠
hypothetical protein, conserved
— OG7
LmxM.18.0600 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
LmxM.23.1630 ⚠
hypothetical protein, conserved
— Both
LmxM.12.0250 ⚠
cysteinyl-tRNA synthetase, putative
— Both
LmxM.24.0320 ⚠
fumarate hydratase, putative
— Both
LmxM.08_29.1960 ⚠
fumarate hydratase, putative
— Both
LmxM.04.0570 ⚠
DENN (AEX-3) domain containing protein, putat
— Both
LmxM.13.0200 ⚠
Lipase (class 3), putative
— Both
LmxM.10.0690 ⚠
hypothetical protein, conserved
— Both
LmxM.18.1040 ⚠
putative 5-oxoprolinase, putative
— Both
LmxM.36.2480 ⚠
hypothetical protein, conserved
— Both
LmxM.30.2170 ⚠
ARM-like helical domain-containing protein
— Both
LmxM.33.2340 ⚠
asparaginyl-tRNA synthetase, putative
— Both
LmxM.24.0490 ⚠
Leucine Rich repeats (2 copies)/Leucine rich
— Both
LmxM.24.2020 ⚠
tubulin folding cofactor D, putative
— Both
LmxM.16.1140 ⚠
WW domain containing protein, putative
— Both
LmxM.27.1350 ⚠
hypothetical protein, unknown function
— Both
LmxM.06.0370 ⚠
glutamine synthetase, putative
— Both
LmxM.09.1300 ⚠
PPPDE putative peptidase domain containing pr
— Both
LmxM.08_29.1700 ⚠
MORN repeat, putative
— Both
LmxM.21.0470 ⚠
vacuolar sorting-associated-like protein
— Both
LmxM.15.0430 ⚠
hypothetical protein, conserved
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.