LmxM.08_29.1960

fumarate hydratase, putative
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_102839 OG7: OG7_0008166 34 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 34 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.24.2060 ⚠
transketolase, putative
— Both
LmxM.05.0830 ⚠
methylthioadenosine phosphorylase, putative
— Both
LmxM.34.3340 ⚠
6-phosphogluconate dehydrogenase, decarboxyla
— Both
LmxM.18.1580 ⚠
nonspecific nucleoside hydrolase
— Both
LmxM.29.2900 ⚠
aldehyde dehydrogenase, putative
— Both
LmxM.15.1010 ⚠
glutamate dehydrogenase
— Both
LmxM.08_29.2140 ⚠
C-8 sterol isomerase-like protein
— Both
LmxM.08_29.0867 ⚠
guanine deaminase, putative
— Both
LmxM.29.3500 ⚠
S-adenosylmethionine synthetase
— Both
LmxM.24.2110 ⚠
3-hydroxy-3-methylglutaryl-CoA synthase, puta
— Both
LmxM.14.0130 ⚠
nucleoside hydrolase-like protein
— Both
LmxM.34.3080 ⚠
glycerol kinase, glycosomal, putative
— Both
LmxM.34.4750 ⚠
glyceraldehyde-3-phosphate dehydrogenase-like
— Both
LmxM.04.0460 ⚠
adenylosuccinate lyase, putative
— Both
LmxM.31.2950 ⚠
nucleoside diphosphate kinase b
— Both
LmxM.31.2951 ⚠
nucleoside diphosphate kinase b
— Both
LmxM.36.5180 ⚠
aldehyde dehydrogenase, putative
— OG7
LmxM.28.2670 ⚠
protein phosphatase 4 catalytic subunit, puta
— OG6
LmxM.24.0761 ⚠
malic enzyme
— Both
LmxM.18.0670 ⚠
citrate synthase, putative
— Both
LmxM.24.0770 ⚠
malic enzyme, putative
— Both
LmxM.18.0680 ⚠
citrate synthase, putative
— Both
LmxM.34.3230 ⚠
cystathione gamma lyase, putative
— Both
LmxM.36.1760 ⚠
aldehyde dehydrogenase, putative
— Both
LmxM.31.3040 ⚠
protein phosphatase 2A catalytic subunit, put
— OG6
LmxM.14.0460 ⚠
cystathionine beta-lyase-like protein
— Both
LmxM.13.1190 ⚠
adenylosuccinate synthetase, putative
— Both
LmxM.36.2350 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— Both
LmxM.29.2980 ⚠
glyceraldehyde 3-phosphate dehydrogenase, gly
— Both
LmxM.14.1160 ⚠
enolase
— Both
LmxM.18.0510 ⚠
aconitase, putative
— Both
LmxM.05.0350 ⚠
trypanothione reductase
— Both
LmxM.12.0630 ⚠
alanine aminotransferase, putative
— Both
LmxM.24.0320 ⚠
fumarate hydratase, putative
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.