LmxM.24.2110

3-hydroxy-3-methylglutaryl-CoA synthase, putative
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_101064 OG7: OG7_0006553 84 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 84 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.20.0560
cytidine triphosphate synthase, putative
— Both
LmxM.08_29.2020 ⚠
5'-AMP-activated protein kinase catalytic sub
— OG7
LmxM.36.0900 ⚠
SNF1-related protein kinases, putative (fragm
— OG7
LmxM.28.2000 ⚠
phosphorylase kinase-like protein
— OG7
LmxM.28.1530 ⚠
DEAD box RNA helicase, putative
— OG7
LmxM.01.0770 ⚠
Eukaryotic initiation factor 4A-1
— OG7
LmxM.34.0370 ⚠
ATP-dependent DEAD-box RNA helicase, putative
— OG7
LmxM.32.1710 ⚠
protein kinase, putative
— OG7
LmxM.29.2590 ⚠
hypothetical protein, conserved
— OG7
LmxM.34.2160 ⚠
adenine aminohydrolase
— OG7
LmxM.15.0240 ⚠
nonspecific lipid-transfer protein, putative,
— OG7
LmxM.22.0810 ⚠
serine/threonine protein kinase sos2, putativ
— OG7
LmxM.15.1160 ⚠
tryparedoxin peroxidase
— Both
LmxM.23.0040 ⚠
tryparedoxin peroxidase, peroxidoxin
— Both
LmxM.23.0690 ⚠
3-ketoacyl-CoA thiolase-like protein
— Both
LmxM.15.1040 ⚠
tryparedoxin peroxidase
— Both
LmxM.31.2951 ⚠
nucleoside diphosphate kinase b
— Both
LmxM.31.2950 ⚠
nucleoside diphosphate kinase b
— Both
LmxM.17.0250 ⚠
cystathionine beta-synthase
— Both
LmxM.36.3590 ⚠
cysteine synthase, putative
— OG6
LmxM.24.1730 ⚠
protein kinase, putative, calcium/calmodulin-
— Both
LmxM.27.1420 ⚠
choline/ethanolamine kinase, putative
— OG7
LmxM.31.2200 ⚠
U5 small nuclear ribonucleoprotein component,
— OG7
LmxM.25.2080 ⚠
elongation factor 2-like protein
— OG7
LmxM.34.2620 ⚠
TFIIF-stimulated CTD phosphatase, putative
— OG7
LmxM.28.1740 ⚠
NOL1/NOP2/sun family, putative
— OG7
LmxM.08_29.2400 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LmxM.30.0190 ⚠
nucleolar protein, putative
— OG7
LmxM.31.0100 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LmxM.31.2430 ⚠
NOL1/NOP2/sun family, putative
— OG7
LmxM.34.3520 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LmxM.26.0160 ⚠
nuclear lim interactor-interacting factor-lik
— OG7
LmxM.08_29.1960 ⚠
fumarate hydratase, putative
— Both
LmxM.25.2030 ⚠
dullard-like phosphatase domain containing pr
— OG7
LmxM.34.0190 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LmxM.36.6780 ⚠
nuclear lim interactor-interacting factor, pu
— OG7
LmxM.08_29.2000 ⚠
hypothetical protein, conserved
— OG7
LmxM.11.0250 ⚠
serine/threonine protein kinase, putative
— OG7
LmxM.34.2320 ⚠
protein kinase, putative
— OG7
LmxM.12.1250 ⚠
metallo-peptidase, Clan MA(E), Family M1, pur
— OG7
LmxM.26.0300 ⚠
aminopeptidase-like protein, metallo-peptidas
— OG7
LmxM.21.0150 ⚠
serine/threonine-protein kinase-like protein
— OG7
LmxM.10.0760
hypothetical protein, conserved
— Both
LmxM.26.0830
asparagine synthetase a, putative, aspartate-
— Both
LmxM.08_29.2240 ⚠
Aminopeptidase M1, putative
— Both
LmxM.18.0640 ⚠
serine/threonine kinase-like protein, putativ
— Both
LmxM.21.1552 ⚠
ATP-dependent RNA helicase SUB2, putative
— Both
LmxM.07.0900 ⚠
protein kinase, putative, serine/threonine ki
— Both
LmxM.36.2950
succinyl-CoA ligase [GDP-forming] beta-chain,
— Both
LmxM.16.0540
aspartate carbamoyltransferase, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.