LmxM.04.0465

hypothetical protein
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_156863 OG7: OG7_0050940 19 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 19 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.25.2380 ⚠
glutathionylspermidine synthase, putative
— Both
LmxM.23.0460 ⚠
trypanothione synthetase, putative
— OG7
LmxM.32.2850 ⚠
D-alanyl-glycyl endopeptidase-like protein, p
— OG7
LmxM.27.1870 ⚠
trypanothione synthetase
— OG7
LmxM.32.2830 ⚠
D-alanyl-glycyl endopeptidase-like protein, p
— OG7
LmxM.04.0960 ⚠
adenylate kinase, putative
— OG7
LmxM.36.1360 ⚠
adenylate kinase, putative
— OG7
LmxM.16.0020 ⚠
AAA domain containing protein, putative
— OG7
LmxM.31.1360 ⚠
RNA capping enzyme, cytoplasmic
— OG7
LmxM.25.2110
KIF-1 binding protein C terminal, putative
— Both
LmxM.06.0620
Putative Phosphatase/Protein of unknown funct
— OG6
LmxM.36.3210 ⚠
14-3-3 protein 1, putative
— Both
LmxM.11.0350 ⚠
14-3-3 protein 2, putative
— Both
LmxM.32.2320
cell division cycle 45 (CDC45), putative
— Both
LmxM.16.0005
anti-silencing protein a-like protein
— Both
LmxM.10.0060
thymidylate kinase-like protein
— Both
LmxM.21.1250 ⚠
adenylate kinase, putative
— Both
LmxM.21.1440
cytochrome b5-like Heme/Steroid binding domai
— Both
LmxM.32.2260
glycosyl hydrolase-like protein
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.