LmxM.15.1450

proliferative cell nuclear antigen (PCNA), putative
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_100882 OG7: OG7_0005136 21 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 21 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.28.1820
Replication factor A protein 1
— Both
LmxM.29.2980 ⚠
glyceraldehyde 3-phosphate dehydrogenase, gly
— OG7
LmxM.36.2350 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG7
LmxM.34.0390
hypothetical protein, conserved
— Both
LmxM.15.0040
Possible lysine decarboxylase, putative
— Both
LmxM.29.3500
S-adenosylmethionine synthetase
— Both
LmxM.14.0980
sodium/hydrogen exchanger, putative
— Both
LmxM.33.1990
Zeta toxin, putative
— Both
LmxM.27.2050 ⚠
ribonucleoside-diphosphate reductase small ch
— Both
LmxM.22.1290 ⚠
ribonucleoside-diphosphate reductase small ch
— Both
LmxM.11.0130
NGG1 interacting factor 3-like protein
— Both
LmxM.34.4750 ⚠
glyceraldehyde-3-phosphate dehydrogenase-like
— Both
LmxM.25.1200
modification methylase-like protein
— Both
LmxM.27.0030 ⚠
queuine tRNA-ribosyltransferase, putative
— Both
LmxM.28.2780 ⚠
heat-shock protein hsp70, putative
— OG6
LmxM.26.1240 ⚠
heat shock protein 70-related protein
— OG6
LmxM.28.2770 ⚠
heat-shock protein hsp70, putative
— OG6
LmxM.28.2820 ⚠
heat shock protein 70, putative
— Both
LmxM.28.1200 ⚠
luminal binding protein 1 (BiP), putative
— OG6
LmxM.29.1800 ⚠
queuine tRNA-ribosyltransferase, putative
— Both
LmxM.30.3090
metallo-peptidase, Clan ME, Family M16, pepti
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.