LmxM.22.0570

proteasome regulatory ATPase subunit 1, putative
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_101899 OG7: OG7_0000949 77 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 77 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.02.0370
proteasome regulatory non-ATPase subunit 6, p
— OG6
LmxM.31.1200
proteasome regulatory non-ATP-ase subunit, pu
— OG6
LmxM.22.0620
proteasome regulatory ATPase subunit 5, putat
— OG6
LmxM.13.1090
proteasome regulatory ATPase subunit 2, putat
— OG6
LmxM.21.0760
proteasome regulatory non-ATP-ase subunit 5,
— OG6
LmxM.03.0540
26S protease regulatory subunit, putative, se
— OG6
LmxM.33.0650
proteasome regulatory non-ATPase subunit 11,
— OG6
LmxM.31.2820
proteasome regulatory non-ATP-ase subunit, pu
— OG6
LmxM.36.4360
Regulatory particle triple-A ATPase subunit 6
— OG6
LmxM.07.1120
proteasome regulatory non-ATP-ase subunit, pu
— OG6
LmxM.19.1120
proteasome regulatory non-ATP-ase subunit 9,
— OG6
LmxM.12.0210
proteasome regulatory ATPase subunittcc1l8.3,
— OG6
LmxM.27.1460
proteasome regulatory non-ATP-ase subunit 3,
— OG6
LmxM.32.0280
hypothetical protein, conserved
— OG6
LmxM.28.1730
proteasome regulatory non-ATP-ase subunit 2,
— OG6
LmxM.08_29.0120
proteasome regulatory non-ATPase subunit, put
— OG6
LmxM.31.0390
19S proteasome non-atpase subunit 8
— OG6
LmxM.19.0690 ⚠
Flagellum attachment zone protein 7
— OG6
LmxM.14.0930
immunodominant antigen, putative, tc40 antige
— OG6
LmxM.24.1960
hypothetical protein, conserved
— OG6
LmxM.31.0970
cysteine peptidase, Clan CA, family C2, putat
— OG6
LmxM.09.1220
AAA family ATPase, putative
— OG6
LmxM.19.0680 ⚠
Flagellum attachment zone protein 7
— OG6
LmxM.04.0690
axonemal dynein light chain, putative
— OG6
LmxM.31.1470
Microtubule-binding protein MIP-T3, putative
— OG6
LmxM.36.6340
HECT E3 ligase, putative
— OG6
LmxM.20.0260
Midasin, putative
— OG6
LmxM.26.1120
axonemal dynein light chain, putative
— OG6
LmxM.09.0800
kinetoplast-associated protein-like protein
— OG6
LmxM.08_29.0970
kinesin, putative
— OG6
LmxM.21.0800
CCR4-NOT transcription complex subunit 1
— OG6
LmxM.26.1950
microtubule-associated protein, putative
— OG6
LmxM.12.0010
translation initiation factor EIF-2b alpha su
— OG6
LmxM.31.0680
OSM3-like kinesin, putative
— OG6
LmxM.33.4530 ⚠
Phosphatidylinositol 3-kinase tor2
— OG6
LmxM.28.0430
hypothetical protein, conserved
— OG6
LmxM.27.2170
hypothetical protein, conserved
— OG6
LmxM.22.1500
ATP-dependent DEAD/H RNA helicase, putative
— OG6
LmxM.36.6320 ⚠
Phosphatidylinositol 3-kinase tor1
— OG6
LmxM.08_29.1180
hypothetical protein, conserved
— OG6
LmxM.31.0310
intraflagellar transport protein 140, putativ
— OG6
LmxM.29.0050
MATH domain containing protein, putative
— OG6
LmxM.29.0490
hypothetical protein, conserved
— OG6
LmxM.32.1490
hypothetical protein, conserved
— OG6
LmxM.33.1510
hypothetical protein, conserved
— OG6
LmxM.25.1840
General negative regulator of transcription s
— OG6
LmxM.23.0900
hypothetical protein, conserved
— OG6
LmxM.01.0190
hypothetical protein, conserved
— OG6
LmxM.15.1200
protein kinase, putative
— OG6
LmxM.21.1330partial
RecF/RecN/SMC N terminal domain/SMC proteins
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.