LmxM.22.1500

ATP-dependent DEAD/H RNA helicase, putative
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_126543 OG7: OG7_0000698 91 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 91 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.08_29.2670
serine/threonine-protein kinase Nek, putative
— OG6
LmxM.08_29.1180
hypothetical protein, conserved
— OG6
LmxM.36.6320 ⚠
Phosphatidylinositol 3-kinase tor1
— OG6
LmxM.29.2730
Stabilization of polarity axis, putative
— OG6
LmxM.36.5760
Rab3 GTPase-activating protein regulatory sub
— OG6
LmxM.27.2170
hypothetical protein, conserved
— OG6
LmxM.34.3280 ⚠
60S ribosomal subunit protein L31, putative
— OG6
LmxM.33.4530 ⚠
Phosphatidylinositol 3-kinase tor2
— OG6
LmxM.31.0680
OSM3-like kinesin, putative
— OG6
LmxM.36.5640
Cyclin 12, L-type
— OG6
LmxM.26.1120
axonemal dynein light chain, putative
— OG6
LmxM.26.1950
microtubule-associated protein, putative
— OG6
LmxM.32.2560
Unc104-like kinesin, putative
— OG6
LmxM.32.2910
hypothetical protein, conserved
— OG6
LmxM.28.0230
hypothetical protein, unknown function
— OG6
LmxM.34.3290 ⚠
60S ribosomal subunit protein L31, putative
— OG6
LmxM.29.3430
protein mkt1, putative
— OG6
LmxM.08_29.1230
COPII coat assembly protein sec16, putative (
— OG6
LmxM.36.0970
hypothetical protein, conserved
— OG6
LmxM.36.6140
hypothetical protein, conserved
— OG6
LmxM.36.6340
HECT E3 ligase, putative
— OG6
LmxM.29.2440
hypothetical protein, conserved
— OG6
LmxM.31.1470
Microtubule-binding protein MIP-T3, putative
— OG6
LmxM.29.0490
hypothetical protein, conserved
— OG6
LmxM.09.1220
AAA family ATPase, putative
— OG6
LmxM.01.0430
Ring finger domain/Zn-finger in ubiquitin-hyd
— OG6
LmxM.12.0010
translation initiation factor EIF-2b alpha su
— OG6
LmxM.15.0920
protein phosphatase 2A regulatory subunit, pu
— OG6
LmxM.16.0730
ubiquitin hydrolase, putative
— OG6
LmxM.06.0190
hypothetical protein, conserved
— OG6
LmxM.18.1450
Protein of unknown function (DUF3648), putati
— OG6
LmxM.22.0570
proteasome regulatory ATPase subunit 1, putat
— OG6
LmxM.04.0350
hypothetical protein
— OG6
LmxM.29.0050
MATH domain containing protein, putative
— OG6
LmxM.25.1430
Putative intraflagellar transport protein A1
— OG6
LmxM.36.2480
hypothetical protein, conserved
— OG6
LmxM.08_29.0970
kinesin, putative
— OG6
LmxM.23.0900
hypothetical protein, conserved
— OG6
LmxM.33.0300
hypothetical protein, conserved
— OG6
LmxM.25.1840
General negative regulator of transcription s
— OG6
LmxM.32.1490
hypothetical protein, conserved
— OG6
LmxM.33.1510
hypothetical protein, conserved
— OG6
LmxM.34.1730
casein kinase II, putative
— OG6
LmxM.31.0310
intraflagellar transport protein 140, putativ
— OG6
LmxM.32.0280
hypothetical protein, conserved
— OG6
LmxM.28.2730
hypothetical protein, conserved
— OG6
LmxM.05.0920
paraflagellar rod protein, putative
— OG6
LmxM.07.0280
HECT E3 ligase, putative
— OG6
LmxM.06.0260 ⚠
5'-3' exoribonuclease A, putative
— OG6
LmxM.36.1790 ⚠
5'-3' exoribonuclease D, putative
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.