LmxM.28.0890

ribonucleoside-diphosphate reductase large chain, putative
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_100448 OG7: OG7_0004229 110 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 110 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.26.0160 ⚠
nuclear lim interactor-interacting factor-lik
— OG7
LmxM.23.0550 ⚠
ubiquitin-activating enzyme E1, putative
— Both
LmxM.23.0690 ⚠
3-ketoacyl-CoA thiolase-like protein
— Both
LmxM.25.0020
n-terminal acetyltransferase complex ard1 sub
— Both
LmxM.16.0540
aspartate carbamoyltransferase, putative
— Both
LmxM.34.3340
6-phosphogluconate dehydrogenase, decarboxyla
— Both
LmxM.05.0830
methylthioadenosine phosphorylase, putative
— Both
LmxM.10.0290
isocitrate dehydrogenase [NADP]
— Both
LmxM.29.0520
N-acetyltransferase B complex (NatB) non cata
— Both
LmxM.36.4930
translation initiation factor 2 subunit, puta
— Both
LmxM.30.0010
5-methyltetrahydropteroyltriglutamate--homocy
— Both
LmxM.08_29.2210
leucine-rich repeat-containing protein
— Both
LmxM.32.1020
PSP1 C-terminal conserved region, putative
— Both
LmxM.31.1790
hypothetical protein, conserved
— Both
LmxM.36.4780
paraflagellar rod component, putative
— Both
LmxM.29.3320
hypothetical protein, conserved
— Both
LmxM.32.0780 ⚠
NLI interacting factor-like phosphatase, puta
— Both
LmxM.32.2050
hypothetical protein, conserved
— Both
LmxM.10.0840 ⚠
hypothetical protein, conserved
— Both
LmxM.24.1730 ⚠
protein kinase, putative, calcium/calmodulin-
— Both
LmxM.28.0450 ⚠
DIS3-like exonuclease, putative
— Both
LmxM.04.0330 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LmxM.28.0330 ⚠
rrp44p homologue, putative
— OG7
LmxM.34.2160 ⚠
adenine aminohydrolase
— OG7
LmxM.29.2590 ⚠
hypothetical protein, conserved
— OG7
LmxM.36.6780 ⚠
nuclear lim interactor-interacting factor, pu
— OG7
LmxM.34.0190 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LmxM.25.2030 ⚠
dullard-like phosphatase domain containing pr
— OG7
LmxM.32.0314 ⚠
heat shock protein 83-1
— OG7
LmxM.15.0240 ⚠
nonspecific lipid-transfer protein, putative,
— OG7
LmxM.31.1570 ⚠
Putative GTPase activating protein for Arf, p
— OG7
LmxM.18.1110 ⚠
Multisite-specific tRNA:(cytosine-C(5))-methy
— OG7
LmxM.33.2340 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
LmxM.11.0620 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
LmxM.15.1300 ⚠
ubiquitin hydrolase, putative
— OG7
LmxM.08_29.0760 ⚠
heat shock protein 90, putative
— OG7
LmxM.34.1740 ⚠
ubiquitin hydrolase, putative
— OG7
LmxM.28.1770 ⚠
Putative GTPase activating protein for Arf, p
— OG7
LmxM.29.0735 ⚠
co-chaperone, GrpE, putative, heat shock prot
— OG7
LmxM.08_29.0330 ⚠
Putative GTPase activating protein for Arf, p
— OG7
LmxM.13.0710 ⚠
Putative GTPase activating protein for Arf, p
— OG7
LmxM.17.1130 ⚠
NOL1/NOP2/sun family, putative
— OG7
LmxM.14.1370 ⚠
tyrosyl-tRNA synthetase, putative
— OG7
LmxM.34.3520 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LmxM.31.0100 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LmxM.08_29.2400 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LmxM.34.2620 ⚠
TFIIF-stimulated CTD phosphatase, putative
— OG7
LmxM.34.2320 ⚠
protein kinase, putative
— OG7
LmxM.11.0250 ⚠
serine/threonine protein kinase, putative
— OG7
LmxM.32.0316 ⚠
heat shock protein 83-1
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.