LmxM.33.0150

malate dehydrogenase, putative
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_192279 OG7: OG7_0004751 63 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 63 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.04.0580 ⚠
spermidine synthase, putative
— OG7
LmxM.36.4450 ⚠
mitochondrial intermediate peptidase, putativ
— OG7
LmxM.29.1380 ⚠
amidohydrolase, putative
— OG7
LmxM.20.1570 ⚠
amidohydrolase, putative
— OG7
LmxM.20.1550 ⚠
amidohydrolase, putative
— OG7
LmxM.05.0350 ⚠
trypanothione reductase
— OG7
LmxM.14.0980 ⚠
sodium/hydrogen exchanger, putative
— OG7
LmxM.30.1130 ⚠
amidohydrolase, putative
— OG7
LmxM.36.6750 ⚠
prolyl endopeptidase
— OG7
LmxM.06.0340 ⚠
serine peptidase, clan SC, family S9A-like pr
— OG7
LmxM.09.0770 ⚠
oligopeptidase b
— OG7
LmxM.20.1560 ⚠
amidohydrolase, putative
— OG7
LmxM.13.0680 ⚠
Metallopeptidase family M24, putative
— OG7
LmxM.19.0160 ⚠
metallo-peptidase, Clan MG, Family M24
— OG7
LmxM.29.0930 ⚠
hypothetical protein, conserved
— OG7
LmxM.08_29.2100 ⚠
Present in the outer mitochondrial membrane p
— OG7
LmxM.33.2610 ⚠
ruvB-like DNA helicase, putative
— OG7
LmxM.01.0830 ⚠
hypothetical protein
— OG7
LmxM.02.0740 ⚠
metallo-peptidase, Clan MA(E), Family M3, pep
— OG7
LmxM.26.1570 ⚠
metallo-peptidase, Clan MA(E), Family M3, thi
— OG7
LmxM.32.2520 ⚠
UDP-N-acetylglucosamine pyrophosphorylase, pu
— OG7
LmxM.21.1552 ⚠
ATP-dependent RNA helicase SUB2, putative
— OG7
LmxM.34.0370 ⚠
ATP-dependent DEAD-box RNA helicase, putative
— OG7
LmxM.01.0770 ⚠
Eukaryotic initiation factor 4A-1
— OG7
LmxM.28.1530 ⚠
DEAD box RNA helicase, putative
— OG7
LmxM.22.1600 ⚠
ser/thr protein phosphatase, putative
— OG7
LmxM.17.0580 ⚠
bis(5'-nucleosyl)-tetraphosphatase, symmetric
— OG7
LmxM.22.0530 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
LmxM.08_29.0300 ⚠
hypothetical protein
— OG7
LmxM.36.6570 ⚠
y113g7b.23 protein-like protein, hypothetical
— OG7
LmxM.15.0300 ⚠
Ecotin-like protein
— OG7
LmxM.15.0520 ⚠
ecotin, putative
— OG7
LmxM.31.1850 ⚠
Chaperonin HSP60, mitochondrial
— OG7
LmxM.25.2130 ⚠
succinyl-CoA synthetase alpha subunit, putati
— OG7
LmxM.34.3440 ⚠
replication factor A protein 3, putative
— OG7
LmxM.15.0050 ⚠
cytochrome-b5 reductase, putative
— OG7
LmxM.25.2140 ⚠
succinyl-CoA synthetase alpha subunit, putati
— OG7
LmxM.36.2950 ⚠
succinyl-CoA ligase [GDP-forming] beta-chain,
— OG7
LmxM.36.2030 ⚠
chaperonin HSP60, mitochondrial precursor
— OG7
LmxM.08_29.2800 ⚠
inosine-adenosine-guanosine-nucleosidehydrola
— OG7
LmxM.26.1710 ⚠
cytochrome c oxidase subunit V, putative
— OG7
LmxM.36.2020 ⚠
chaperonin HSP60, mitochondrial precursor
— OG7
LmxM.36.6650 ⚠
2,3-bisphosphoglycerate-independentphosphogly
— OG7
LmxM.13.1060 ⚠
NADH-cytochrome b5 reductase, putative
— OG7
LmxM.11.0270 ⚠
NADH-cytochrome b5 reductase-like protein
— OG7
LmxM.24.0850 ⚠
triosephosphate isomerase
— OG7
LmxM.29.1250 ⚠
pyridoxal kinase, putative
— OG7
LmxM.23.0460 ⚠
trypanothione synthetase, putative
— OG7
LmxM.07.0190 ⚠
phosphotyrosyl phosphate activator protein, p
— OG7
LmxM.32.2830 ⚠
D-alanyl-glycyl endopeptidase-like protein, p
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.