LmxM.36.6750

prolyl endopeptidase
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_101804 OG7: OG7_0003174 52 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 52 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.26.2640 ⚠
hypothetical protein, conserved
— OG7
LmxM.29.3420 ⚠
T-complex protein 11, putative
— OG7
LmxM.26.2000 ⚠
methyltransferase domain containing protein,
— OG7
LmxM.34.3260 ⚠
Peroxin 19
— OG7
LmxM.34.0900 ⚠
hypothetical protein, conserved
— OG7
LmxM.29.0930 ⚠
hypothetical protein, conserved
— OG7
LmxM.08_29.2100 ⚠
Present in the outer mitochondrial membrane p
— OG7
LmxM.05.0350 ⚠
trypanothione reductase
— OG7
LmxM.08_29.2240 ⚠
Aminopeptidase M1, putative
— OG7
LmxM.12.1250 ⚠
metallo-peptidase, Clan MA(E), Family M1, pur
— OG7
LmxM.36.4450 ⚠
mitochondrial intermediate peptidase, putativ
— OG7
LmxM.34.0350 ⚠
hypothetical protein, conserved
— OG7
LmxM.29.3130 ⚠
valyl-tRNA synthetase, putative
— OG7
LmxM.23.0460 ⚠
trypanothione synthetase, putative
— OG7
LmxM.29.1380 ⚠
amidohydrolase, putative
— OG7
LmxM.20.0250 ⚠
deoxyhypusine synthase, putative
— OG7
LmxM.20.1570 ⚠
amidohydrolase, putative
— OG7
LmxM.20.1550 ⚠
amidohydrolase, putative
— OG7
LmxM.36.3840 ⚠
glycyl tRNA synthetase, putative
— OG7
LmxM.14.0980 ⚠
sodium/hydrogen exchanger, putative
— OG7
LmxM.04.0990 ⚠
hypothetical protein, conserved
— OG7
LmxM.30.1130 ⚠
amidohydrolase, putative
— OG7
LmxM.19.0940 ⚠
CAP-Gly domain containing protein, putative
— OG7
LmxM.20.1560 ⚠
amidohydrolase, putative
— OG7
LmxM.33.0330 ⚠
deoxyhypusine synthase, putative
— OG7
LmxM.13.1100 ⚠
leucyl-tRNA synthetase, putative
— OG7
LmxM.30.3090 ⚠
metallo-peptidase, Clan ME, Family M16, pepti
— OG7
LmxM.27.1640 ⚠
BRO1-like domain/ALIX V-shaped domain binding
— Both
LmxM.09.0840 ⚠
Uncharacterised protein family (UPF0160), put
— Both
LmxM.18.0460 ⚠
tubulin-specific chaperone, putative
— Both
LmxM.32.1380 ⚠
mitogen activated protein kinase, putative
— OG6
LmxM.19.1440 ⚠
mitogen-activated protein kinase 4
— OG6
LmxM.01.0830 ⚠
hypothetical protein
— Both
LmxM.02.0740 ⚠
metallo-peptidase, Clan MA(E), Family M3, pep
— Both
LmxM.26.1570 ⚠
metallo-peptidase, Clan MA(E), Family M3, thi
— Both
LmxM.27.1870 ⚠
trypanothione synthetase
— Both
LmxM.26.0300 ⚠
aminopeptidase-like protein, metallo-peptidas
— Both
LmxM.08_29.0940 ⚠
hypothetical protein, conserved
— Both
LmxM.22.0590 ⚠
Uncharacterised protein family UPF0066, putat
— OG7
LmxM.36.4930 ⚠
translation initiation factor 2 subunit, puta
— Both
LmxM.33.3500 ⚠
ruvb-like 1 DNA helicase, putative
— OG7
LmxM.33.2610 ⚠
ruvB-like DNA helicase, putative
— OG7
LmxM.03.0200 ⚠
delta-1-pyrroline-5-carboxylate dehydrogenase
— OG7
LmxM.36.2420 ⚠
serine peptidase, Clan SC, Family S9B
— OG7
LmxM.19.0710 ⚠
glycosomal malate dehydrogenase
— OG7
LmxM.33.0140 ⚠
malate dehydrogenase
— OG7
LmxM.33.0130 ⚠
malate dehydrogenase, putative
— OG7
LmxM.33.0160 ⚠
malate dehydrogenase, putative
— OG7
LmxM.33.0150 ⚠
malate dehydrogenase, putative
— OG7
LmxM.32.2830 ⚠
D-alanyl-glycyl endopeptidase-like protein, p
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.