LpyrH10_03_3780

GDP-mannose pyrophosphorylase, putative mitochondrial

Leptomonas pyrrhocoris H10 OG6: OG6_100460 OG7: OG7_0001668 205 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Query Computational only Exp + computational Experimental only

Interactions 205 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LpyrH10_03_0470 glutamine synthetase, putative	—	OG6 Tb927.7.4970 ↔ Tb927.8.2050 OG6 TCSYLVIO_001811 ↔ TCSYLVIO_007603 OG7 Tb927.7.4970 ↔ Tb927.8.2050 OG7 TCSYLVIO_001811 ↔ TCSYLVIO_007603	Both
LpyrH10_36_0260 ⚠ inorganic pyrophosphatase, putative, putative	—	OG6 Tb927.11.7080 ↔ Tb927.8.2050 OG6 TCSYLVIO_001709 ↔ TCSYLVIO_007603 OG7 Tb927.11.7080 ↔ Tb927.8.2050 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_007603	Both
LpyrH10_18_0240 ⚠ acidocalcisomal pyrophosphatase	—	OG6 Tb927.11.7080 ↔ Tb927.8.2050 OG6 TCSYLVIO_001709 ↔ TCSYLVIO_007603 OG7 Tb927.11.7080 ↔ Tb927.8.2050 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_007603	Both
LpyrH10_17_1660 myo-inositol-1-phosphate synthase,inositol-3-	—	OG6 TCSYLVIO_007453 ↔ TCSYLVIO_007603 OG6 Tb927.10.7110 ↔ Tb927.8.2050 OG7 Tb927.10.7110 ↔ Tb927.8.2050 OG7 TCSYLVIO_007453 ↔ TCSYLVIO_007603	Both
LpyrH10_09_1360 ⚠ endonuclease/exonuclease/phosphatase, putativ	—	OG7 TCSYLVIO_007569 ↔ TCSYLVIO_007603	OG7
LpyrH10_17_1600 ⚠ serine hydroxymethyltranferase (SHMT-S) (SHMT	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_010621 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_010621	Both
LpyrH10_02_3620 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_000468 ↔ TCSYLVIO_007603	OG7
LpyrH10_03_4720 ⚠ GTP binding protein, putative, putative mitoc	—	OG7 TCSYLVIO_000468 ↔ TCSYLVIO_007603	OG7
LpyrH10_09_0180 ⚠ fructose-6-phosphate2-kinase/fructose-2,6-bis	—	OG7 TCSYLVIO_002376 ↔ TCSYLVIO_007603	OG7
LpyrH10_30_0460 ⚠ 6-phosphofructo-2-kinase-like protein, putati	—	OG7 TCSYLVIO_002376 ↔ TCSYLVIO_007603	OG7
LpyrH10_36_0130 ⚠ 6-phosphofructo-2-kinase/fructose-2,6-biphosp	—	OG7 TCSYLVIO_002376 ↔ TCSYLVIO_007603	OG7
LpyrH10_02_4220 ⚠ hypothetical protein, conserved, putative mit	—	OG7 Tb927.11.12670 ↔ Tb927.8.2050	OG7
LpyrH10_05_3640 ⚠ Cleavage and polyadenylation specificity fact	—	OG7 TCSYLVIO_005414 ↔ TCSYLVIO_007603	OG7
LpyrH10_24_0300 ⚠ mitochondrial exoribonuclease DSS-1, putative	—	OG7 TCSYLVIO_002525 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_007603	OG7
LpyrH10_02_7830 ⚠ Rrp44p homologue, putative	—	OG7 TCSYLVIO_002525 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_007603	OG7
LpyrH10_07_2160 ⚠ aminopeptidase, putative,metallo-peptidase, C	—	OG7 TCSYLVIO_001670 ↔ TCSYLVIO_007603	OG7
LpyrH10_06_1990 paraflagellar rod component, putative	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_007603	OG6
LpyrH10_01_2390 vacuolar ATP synthase subunit d, putative	—	OG6 TCSYLVIO_005104 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_005104 ↔ TCSYLVIO_007603	Both
LpyrH10_10_2850 hypothetical protein, conserved	—	OG6 TCSYLVIO_006421 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_006421 ↔ TCSYLVIO_007603	Both
LpyrH10_22_1630 ⚠ Hypothetical protein, conserved	—	OG6 TCSYLVIO_003586 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_003586 ↔ TCSYLVIO_007603	Both
LpyrH10_31_1040 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_003586 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_003586 ↔ TCSYLVIO_007603	Both
LpyrH10_02_4440 Hypothetical protein, conserved	—	OG6 TCSYLVIO_000836 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_000836 ↔ TCSYLVIO_007603	Both
LpyrH10_03_3170 ⚠ Poly(A)-specific ribonuclease PARN, putative,	—	OG6 TCSYLVIO_000055 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_000055 ↔ TCSYLVIO_007603	Both
LpyrH10_06_4470 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_000055 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_000055 ↔ TCSYLVIO_007603	Both
LpyrH10_02_7700 ⚠ ribonuclease II-like protein, putative	—	OG6 TCSYLVIO_002525 ↔ TCSYLVIO_007603 OG6 TCSYLVIO_002526 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_002525 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_007603	Both
LpyrH10_01_1540 Alanyl-tRNA synthetase, putative, putative mi	—	OG6 TCSYLVIO_001889 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_001889 ↔ TCSYLVIO_007603	Both
LpyrH10_10_0210 ⚠ cleavage and polyadenylation specificity fact	—	OG6 TCSYLVIO_005414 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_005414 ↔ TCSYLVIO_007603	Both
LpyrH10_29_0020 hypothetical protein, conserved	—	OG6 TCSYLVIO_003958 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_003958 ↔ TCSYLVIO_007603	Both
LpyrH10_11_2350 tubulin folding cofactor D, putative	—	OG6 TCSYLVIO_001302 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_007603	Both
LpyrH10_19_1600 ⚠ heat shock protein 83-1	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_008621 OG6 TCSYLVIO_007603 ↔ TCSYLVIO_009400 OG6 TCSYLVIO_007603 ↔ TCSYLVIO_009151 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_008621 +2 more	Both
LpyrH10_14_0070 ⚠ Hypothetical protein, conserved	—	OG7 TCSYLVIO_006877 ↔ TCSYLVIO_007603	OG7
LpyrH10_17_1690 ⚠ tyrosyl-tRNA synthetase, putative (TyrS)	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_010624 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_010624	Both
LpyrH10_21_0240 ⚠ Hypothetical protein, conserved	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_009102 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_009102	Both
LpyrH10_02_5200 ⚠ Serine hydroxymethyltransferaseserine hydroxy	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_010621 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_010621	Both
LpyrH10_19_1610 ⚠ heat shock protein 83-1	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_008621 OG6 TCSYLVIO_007603 ↔ TCSYLVIO_009400 OG6 TCSYLVIO_007603 ↔ TCSYLVIO_009151 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_008621 +2 more	Both
LpyrH10_12_1340 hypothetical protein, conserved	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_008932 OG6 TCSYLVIO_007603 ↔ TCSYLVIO_010148 OG6 TCSYLVIO_007603 ↔ TCSYLVIO_010257 OG6 TCSYLVIO_000702 ↔ TCSYLVIO_007603 +2 more	OG6
LpyrH10_25_0130 hypothetical protein, conserved	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_008409 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_008409	Both
LpyrH10_06_0630 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_009198 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_009198	Both
LpyrH10_19_1640 ⚠ heat shock protein 83-1	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_008621 OG6 TCSYLVIO_007603 ↔ TCSYLVIO_009400 OG6 TCSYLVIO_007603 ↔ TCSYLVIO_009151 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_008621 +2 more	Both
LpyrH10_28_0930 ⚠ ubiquitin-activating enzyme-like protein	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_010542 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_010542	Both
LpyrH10_19_1630 ⚠ heat shock protein 83-1	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_008621 OG6 TCSYLVIO_007603 ↔ TCSYLVIO_009400 OG6 TCSYLVIO_007603 ↔ TCSYLVIO_009151 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_008621 +2 more	Both
LpyrH10_19_1620 ⚠ heat shock protein 83-1	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_008621 OG6 TCSYLVIO_007603 ↔ TCSYLVIO_009400 OG6 TCSYLVIO_007603 ↔ TCSYLVIO_009151 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_008621 +2 more	Both
LpyrH10_03_3550 pteridine reductase 1	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_008848 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_008848	Both
LpyrH10_09_0100 ⚠ Stress-inducible protein STI1 homolog	—	OG6 TCSYLVIO_003496 ↔ TCSYLVIO_007603	OG6
LpyrH10_03_4070 ⚠ TPR-repeat protein, putative	—	OG6 TCSYLVIO_003496 ↔ TCSYLVIO_007603	OG6
LpyrH10_03_4140 ⚠ GTP binding protein, putative	—	OG6 TCSYLVIO_000468 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_000468 ↔ TCSYLVIO_007603	Both
LpyrH10_16_1200 ⚠ hypothetical protein, conserved	—	OG6 Tb927.11.12670 ↔ Tb927.8.2050 OG7 Tb927.11.12670 ↔ Tb927.8.2050	Both
LpyrH10_07_0230 dihydrolipoamide branched chain transacylase,	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_009880 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_009880	Both
LpyrH10_06_0620 ⚠ Hypothetical protein, conserved	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_009198 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_009198	Both
LpyrH10_05_2090 hypothetical protein, conserved	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_010958 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_010958	Both

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