LpyrH10_36_0260

inorganic pyrophosphatase, putative, putative mitochondrial

Leptomonas pyrrhocoris H10 OG6: OG6_100346 OG7: OG7_0003350 310 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 310 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LpyrH10_04_3020 ⚠ aspartyl-tRNA synthetase, putative	—	OG7 Tb927.11.7060 ↔ Tb927.4.2310 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_003867	OG7
LpyrH10_33_0700 ⚠ ubiquitin activating enzyme, putative, putati	—	OG7 Tb927.11.7060 ↔ Tb927.5.3430 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_010542	OG7
LpyrH10_14_1160 ⚠ aspartyl-tRNA synthetase, putative, putative	—	OG7 Tb927.11.7060 ↔ Tb927.4.2310 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_003867	OG7
LpyrH10_01_1710 ⚠ pyruvate kinase	—	OG6 Tb927.10.14140 ↔ Tb927.11.7060 OG6 TCSYLVIO_004455 ↔ TCSYLVIO_006133 OG7 Tb927.10.14140 ↔ Tb927.11.7060 OG7 TCSYLVIO_004455 ↔ TCSYLVIO_006133	Both
LpyrH10_01_1720 ⚠ pyruvate kinase	—	OG6 Tb927.10.14140 ↔ Tb927.11.7060 OG6 TCSYLVIO_004455 ↔ TCSYLVIO_006133 OG7 Tb927.10.14140 ↔ Tb927.11.7060 OG7 TCSYLVIO_004455 ↔ TCSYLVIO_006133	Both
LpyrH10_05_2510 ⚠ asparaginyl-tRNA synthetase, putative, putati	—	OG6 Tb927.11.7060 ↔ Tb927.4.2310 OG6 TCSYLVIO_001709 ↔ TCSYLVIO_003867 OG7 Tb927.11.7060 ↔ Tb927.4.2310 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_003867	Both
LpyrH10_25_0630 ⚠ calpain-like cysteine peptidase, putative,cys	—	OG6 Tb927.11.7060 ↔ Tb927.9.7540 OG6 TCSYLVIO_001709 ↔ TCSYLVIO_007342	OG6
LpyrH10_12_1340 ⚠ hypothetical protein, conserved	—	OG6 Tb927.11.7060 ↔ Tb927.2.450 OG6 TCSYLVIO_000702 ↔ TCSYLVIO_001709 OG6 TCSYLVIO_001709 ↔ TCSYLVIO_003670 OG6 TCSYLVIO_001709 ↔ TCSYLVIO_008932 +4 more	OG6
LpyrH10_25_0620 ⚠ calpain-like cysteine peptidase, putative,cys	—	OG6 Tb927.11.7060 ↔ Tb927.9.7540 OG6 TCSYLVIO_001709 ↔ TCSYLVIO_007342	OG6
LpyrH10_28_0930 ⚠ ubiquitin-activating enzyme-like protein	—	OG6 Tb927.11.7060 ↔ Tb927.5.3430 OG6 TCSYLVIO_001709 ↔ TCSYLVIO_010542 OG7 Tb927.11.7060 ↔ Tb927.5.3430 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_010542	Both
LpyrH10_24_0510 ⚠ calpain-like cysteine peptidase, putative,cys	—	OG6 Tb927.11.7060 ↔ Tb927.9.7540 OG6 TCSYLVIO_001709 ↔ TCSYLVIO_007342	OG6
LpyrH10_03_3780 ⚠ GDP-mannose pyrophosphorylase, putative mitoc	—	OG6 Tb927.11.7080 ↔ Tb927.8.2050 OG6 TCSYLVIO_001709 ↔ TCSYLVIO_007603 OG7 Tb927.11.7080 ↔ Tb927.8.2050 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_007603	Both
LpyrH10_13_1310 ⚠ UDP-glucose pyrophosphorylase	—	OG6 TCSYLVIO_004455 ↔ TCSYLVIO_006226 OG7 TCSYLVIO_004455 ↔ TCSYLVIO_006226	Both
LpyrH10_02_4220 ⚠ hypothetical protein, conserved, putative mit	—	OG7 Tb927.11.12670 ↔ Tb927.11.7080	OG7
LpyrH10_29_1030 ⚠ aldehyde reductase, putative, putative mitoch	—	OG7 TCSYLVIO_001508 ↔ TCSYLVIO_004455	OG7
LpyrH10_03_4050 ⚠ aldo-keto reductase-like protein, putative mi	—	OG7 TCSYLVIO_001508 ↔ TCSYLVIO_004455	OG7
LpyrH10_28_0440 ⚠ hypothetical protein, unknown function	—	OG7 TCSYLVIO_000168 ↔ TCSYLVIO_004455	OG7
LpyrH10_41_0040 ⚠ MCAK-like kinesin, putative	—	OG7 TCSYLVIO_001515 ↔ TCSYLVIO_004455	OG7
LpyrH10_20_0120 ⚠ MCAK-like kinesin, putative	—	OG7 TCSYLVIO_001515 ↔ TCSYLVIO_004455	OG7
LpyrH10_20_1720 ⚠ Mcak-like kinesin, putative	—	OG7 TCSYLVIO_001515 ↔ TCSYLVIO_004455	OG7
LpyrH10_32_0800 ⚠ Mitotic centromere-associated kinesin (MCAK),	—	OG7 TCSYLVIO_001515 ↔ TCSYLVIO_004455	OG7
LpyrH10_07_2160 ⚠ aminopeptidase, putative,metallo-peptidase, C	—	OG7 TCSYLVIO_001670 ↔ TCSYLVIO_001709	OG7
LpyrH10_01_2390 ⚠ vacuolar ATP synthase subunit d, putative	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_005104 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_005104	Both
LpyrH10_10_1150 ⚠ protein kinase, putative	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_007401 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_007401	Both
LpyrH10_07_0230 ⚠ dihydrolipoamide branched chain transacylase,	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_009880 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_009880	Both
LpyrH10_02_7700 ⚠ ribonuclease II-like protein, putative	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_002526 OG6 TCSYLVIO_001709 ↔ TCSYLVIO_002525 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_002526 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_002525	Both
LpyrH10_07_2880 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_005619 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_005619	Both
LpyrH10_10_2650 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_006404 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_006404	Both
LpyrH10_01_4900 ⚠ acyl-CoA dehydrogenase, putative, putative mi	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_005872 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_005872	Both
LpyrH10_10_0210 ⚠ cleavage and polyadenylation specificity fact	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_005414 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_005414	Both
LpyrH10_01_3960 ⚠ alpha glucosidase II subunit, putative	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_006140 OG6 TCSYLVIO_001709 ↔ TCSYLVIO_006141 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_006140 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_006141	Both
LpyrH10_08_0390 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_004455 ↔ TCSYLVIO_010701 OG7 TCSYLVIO_004455 ↔ TCSYLVIO_010701	Both
LpyrH10_01_1240 ⚠ translation initiation factor IF-2, putative,	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_001768 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_001768	Both
LpyrH10_22_1630 ⚠ Hypothetical protein, conserved	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_003586 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_003586	Both
LpyrH10_05_2530 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_003865 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_003865	Both
LpyrH10_04_5080 ⚠ hypothetical protein, conserved, putative mit	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_003268 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_003268	Both
LpyrH10_04_0270 ⚠ C-terminal motor kinesin, putative	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_006065	OG6
LpyrH10_10_2850 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_006421 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_006421	Both
LpyrH10_06_0620 ⚠ Hypothetical protein, conserved	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_009198 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_009198	Both
LpyrH10_03_3550 ⚠ pteridine reductase 1	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_008848 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_008848	Both
LpyrH10_08_0090 ⚠ tryptophanyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_010724 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_010724	Both
LpyrH10_04_6510 ⚠ DNA ligase I, putative	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_003375 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_003375	Both
LpyrH10_19_0760 ⚠ nicotinate phosphoribosyltransferase, putativ	—	OG6 TCSYLVIO_004455 ↔ TCSYLVIO_004898 OG7 TCSYLVIO_004455 ↔ TCSYLVIO_004898	Both
LpyrH10_14_0080 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_004455 ↔ TCSYLVIO_006876 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_006877 OG7 TCSYLVIO_004455 ↔ TCSYLVIO_006876	Both
LpyrH10_13_0100 ⚠ alpha glucosidase II subunit, putative	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_006140 OG6 TCSYLVIO_001709 ↔ TCSYLVIO_006141 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_006140 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_006141	Both
LpyrH10_03_4150 ⚠ protein phosphatase-like protein	—	OG6 TCSYLVIO_004455 ↔ TCSYLVIO_007482	OG6
LpyrH10_34_0740 ⚠ quinone oxidoreductase, putative	—	OG6 TCSYLVIO_004455 ↔ TCSYLVIO_004489 OG7 TCSYLVIO_004455 ↔ TCSYLVIO_004489	Both
LpyrH10_19_1620 ⚠ heat shock protein 83-1	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_008621 OG6 TCSYLVIO_001709 ↔ TCSYLVIO_009400 OG6 TCSYLVIO_001709 ↔ TCSYLVIO_009151 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_008621 +2 more	Both
LpyrH10_19_1630 ⚠ heat shock protein 83-1	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_008621 OG6 TCSYLVIO_001709 ↔ TCSYLVIO_009400 OG6 TCSYLVIO_001709 ↔ TCSYLVIO_009151 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_008621 +2 more	Both
LpyrH10_19_1600 ⚠ heat shock protein 83-1	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_008621 OG6 TCSYLVIO_001709 ↔ TCSYLVIO_009400 OG6 TCSYLVIO_001709 ↔ TCSYLVIO_009151 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_008621 +2 more	Both

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