LpyrH10_05_0570

eukaryotic translation initiation factor 5, putative

Leptomonas pyrrhocoris H10 OG6: OG6_101859 OG7: OG7_0007078 57 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Query Computational only Exp + computational Experimental only

Interactions 57 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LpyrH10_14_2360 ⚠ 20S proteasome subunit alpha 5, (putative)	—	OG7 TCSYLVIO_001707 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_009369	OG7
LpyrH10_21_1450 translation initiation factor, putative	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_008900 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_008900	Both
LpyrH10_07_2850 ⚠ phosphoribosylpyrophosphate synthetase, putat	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_004731 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_004731	Both
LpyrH10_23_1390 ⚠ Proteasome beta-1 subunit, putative	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_006999 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_006999	Both
LpyrH10_06_1400 ⚠ 60S ribosomal protein L10a, putative (RPL10a)	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_006190 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_006190	Both
LpyrH10_01_5430 ⚠ ATP-dependent RNA helicase, putative	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_005835 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005835	Both
LpyrH10_01_4350 ATP-dependent RNA helicase-like protein	—	OG6 TCSYLVIO_001373 ↔ TCSYLVIO_004556	OG6
LpyrH10_04_6060 eukaryotic translation initiation factor 3 su	—	OG6 TCSYLVIO_003333 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_003333 ↔ TCSYLVIO_004556	Both
LpyrH10_29_1150 acetyl-CoA carboxylase, putative, putative mi	—	OG6 TCSYLVIO_002772 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_002772 ↔ TCSYLVIO_004556	Both
LpyrH10_18_0280 ⚠ Proteasome alpha 7 subunit, putative	—	OG6 TCSYLVIO_001707 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_009369	Both
LpyrH10_02_8070 Proteasome beta 3 subunit, putative	—	OG6 TCSYLVIO_001736 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_004556	Both
LpyrH10_07_1540 ⚠ T-complex protein 1, beta subunit, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_008271	OG7
LpyrH10_01_6200 ⚠ T-complex protein 1, eta subunit, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_008271	OG7
LpyrH10_20_0060 ⚠ chaperonin TCP20, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_008271	OG7
LpyrH10_06_5180 ⚠ Chaperonin, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_008271	OG7
LpyrH10_14_1380 ⚠ T-complex protein 1, delta subunit, putative	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_008271 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_008271	Both
LpyrH10_17_0330 ⚠ proteasome alpha 3 subunit, putative, putativ	—	OG7 TCSYLVIO_001707 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_009369	OG7
LpyrH10_09_1870 ⚠ Proteasome alpha 1 subunit, putative, putativ	—	OG7 TCSYLVIO_001707 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_009369	OG7
LpyrH10_35_0530 ⚠ proteasome alpha 7 subunit, putative	—	OG7 TCSYLVIO_001707 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_009369	OG7
LpyrH10_06_0510 ⚠ ATP-dependent RNA helicase, putative	—	OG7 TCSYLVIO_004479 ↔ TCSYLVIO_004556	OG7
LpyrH10_30_0980 ⚠ ATP-dependent DEAD/H RNA helicase, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005835	OG7
LpyrH10_09_1930 ⚠ proteasome beta 5 subunit, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_006999	OG7
LpyrH10_02_0480 ⚠ Atp-dependent RNA helicase, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005835	OG7
LpyrH10_28_0640 ⚠ ribose-phosphate pyrophosphokinase, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_004731	OG7
LpyrH10_09_2540 ⚠ DEAD box RNA helicase, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005835	OG7
LpyrH10_22_0280 ⚠ DEAD/DEAH box helicase, putative, putative mi	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005835	OG7
LpyrH10_02_5550 ⚠ mitochondrial DEAD box protein, putative, put	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005835	OG7
LpyrH10_04_0310 ⚠ RNA binding protein, putative, putative mitoc	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_006059	OG7
LpyrH10_28_1100 ⚠ Atp-dependent DEAD/H RNA helicase, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005835	OG7
LpyrH10_07_1120 ⚠ 2-oxoglutarate dehydrogenase E1 component, pu	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_005469 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005469	Both
LpyrH10_05_2920 Hypothetical protein, conserved	—	OG6 TCSYLVIO_003837 ↔ TCSYLVIO_004556	OG6
LpyrH10_06_2720 hypothetical protein, conserved, putative mit	—	OG6 Tb927.10.2770 ↔ Tb927.11.11010 OG7 Tb927.10.2770 ↔ Tb927.11.11010	Both
LpyrH10_02_3420 ⚠ ATP binding protein-like protein	—	OG6 TCSYLVIO_000453 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_000453 ↔ TCSYLVIO_004556	Both
LpyrH10_03_4290 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_000453 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_000453 ↔ TCSYLVIO_004556	Both
LpyrH10_04_3130 spliceosome-associated protein, putative	—	OG6 TCSYLVIO_003119 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_003119 ↔ TCSYLVIO_004556	Both
LpyrH10_36_0020 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_004479 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004479 ↔ TCSYLVIO_004556	Both
LpyrH10_05_3290 exosome subunit rrp6p homologue, putative	—	OG6 TCSYLVIO_003804 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_003804 ↔ TCSYLVIO_004556	Both
LpyrH10_02_3980 ⚠ exosome-associated protein 2, putative	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_004556	Both
LpyrH10_01_1590 ⚠ exosome complex exonuclease RRP45 homolog, pu	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_004556	Both
LpyrH10_18_0340 hypothetical protein, conserved, putative mit	—	OG6 TCSYLVIO_001704 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_001704 ↔ TCSYLVIO_004556	Both
LpyrH10_03_2130 ⚠ T-complex protein 1, gamma subunit, putative	—	OG6 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_008271	Both
LpyrH10_02_1200 ⚠ chaperonin containing t-complex protein, puta	—	OG6 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_008271	Both
LpyrH10_34_0160 acetyltransferase, putative	—	OG6 TCSYLVIO_004519 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004519 ↔ TCSYLVIO_004556	Both
LpyrH10_08_1760 hypothetical protein, conserved, putative mit	—	OG6 TCSYLVIO_004312 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004312 ↔ TCSYLVIO_004556	Both
LpyrH10_30_0370 splicing factor ptsr1-like protein	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_009720 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_009720	Both
LpyrH10_06_3270 ⚠ phosphoribosylpyrophosphate synthetase, putat	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_004731 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_004731	Both
LpyrH10_14_2210 ⚠ Proteasome alpha 2 subunit, putative	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_009369	Both
LpyrH10_01_7250 ⚠ proteasome alpha 1 subunit, putative	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_009369	Both
LpyrH10_06_1070 ⚠ 2-oxoglutarate dehydrogenase E1 component, pu	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_005469 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005469	Both
LpyrH10_13_0880 ⚠ 60S ribosomal protein L10a, putative (RPL10a)	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_006190 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_006190	Both

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