LpyrH10_25_1720

deoxyhypusine synthase, putative

Leptomonas pyrrhocoris H10 OG6: OG6_101093 OG7: OG7_0005231 149 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Query Computational only Exp + computational Experimental only

Interactions 149 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LpyrH10_05_0550 ⚠ deoxyhypusine synthase, putative	—	OG6 TCSYLVIO_004558 ↔ TCSYLVIO_007258 OG6 Tb927.1.870 ↔ Tb927.10.2750 OG7 Tb927.1.870 ↔ Tb927.10.2750 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_007258	Both
LpyrH10_04_6330 ⚠ Uv excision repair RAD23-like protein	—	OG6 TCSYLVIO_003361 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_003361 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_003361 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_003361 ↔ TCSYLVIO_007258	Both
LpyrH10_08_2510 ⚠ UDP-glucose:glycoprotein glucosyltransferase,	—	OG6 TCSYLVIO_004363 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_004363 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_004363 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_004363 ↔ TCSYLVIO_007258	Both
LpyrH10_13_0010 ⚠ kinetoplast polyadenylation/uridylation facto	—	OG6 TCSYLVIO_000834 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_000834 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_000834 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_000834 ↔ TCSYLVIO_007258	Both
LpyrH10_37_0020 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_001973 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_001973 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_001973 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_001973 ↔ TCSYLVIO_007258	Both
LpyrH10_16_1340 ⚠ oligopeptidase b (OPB), putative mitochondria	—	OG6 TCSYLVIO_006546 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_006546 ↔ TCSYLVIO_007258	Both
LpyrH10_03_0440 ⚠ oligopeptidase B-like protein,serine peptidas	—	OG6 TCSYLVIO_006546 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_006546 ↔ TCSYLVIO_007258	Both
LpyrH10_01_1240 ⚠ translation initiation factor IF-2, putative,	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_001768 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_007258	Both
LpyrH10_01_0530 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_001255 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_001255 ↔ TCSYLVIO_007258	Both
LpyrH10_01_9280 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_002279 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_002279 ↔ TCSYLVIO_004558	Both
LpyrH10_03_4070 ⚠ TPR-repeat protein, putative	—	OG6 TCSYLVIO_003496 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_003496 ↔ TCSYLVIO_007258	OG6
LpyrH10_09_0100 ⚠ Stress-inducible protein STI1 homolog	—	OG6 TCSYLVIO_003496 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_003496 ↔ TCSYLVIO_007258	OG6
LpyrH10_01_1540 ⚠ Alanyl-tRNA synthetase, putative, putative mi	—	OG6 TCSYLVIO_001889 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_001889 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_001889 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_001889 ↔ TCSYLVIO_007258	Both
LpyrH10_02_7700 ⚠ ribonuclease II-like protein, putative	—	OG6 TCSYLVIO_002525 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_002526 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_002525 ↔ TCSYLVIO_007258 OG6 TCSYLVIO_002526 ↔ TCSYLVIO_007258 +4 more	Both
LpyrH10_02_4440 ⚠ Hypothetical protein, conserved	—	OG6 TCSYLVIO_000836 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_000836 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_000836 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_000836 ↔ TCSYLVIO_007258	Both
LpyrH10_18_0240 ⚠ acidocalcisomal pyrophosphatase	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_001709 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_007258	Both
LpyrH10_36_0260 ⚠ inorganic pyrophosphatase, putative, putative	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_001709 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_007258	Both
LpyrH10_07_3170 ⚠ protein kinase, putative	—	OG7 TCSYLVIO_004355 ↔ TCSYLVIO_004558	OG7
LpyrH10_01_0770 ⚠ serine/threonine protein kinase sos2, putativ	—	OG7 TCSYLVIO_004355 ↔ TCSYLVIO_004558	OG7
LpyrH10_09_1040 ⚠ protein kinase, putative	—	OG7 TCSYLVIO_004355 ↔ TCSYLVIO_004558	OG7
LpyrH10_14_0210 ⚠ serine/threonine-protein kinase-like protein	—	OG7 TCSYLVIO_004355 ↔ TCSYLVIO_004558	OG7
LpyrH10_13_0900 ⚠ serine/threonine kinase-like protein, putativ	—	OG7 TCSYLVIO_004355 ↔ TCSYLVIO_004558	OG7
LpyrH10_02_5630 ⚠ protein kinase, putative,phosphorylase kinase	—	OG7 TCSYLVIO_004355 ↔ TCSYLVIO_004558	OG7
LpyrH10_30_0340 ⚠ serine/threonine kinase, putative,protein kin	—	OG7 TCSYLVIO_004355 ↔ TCSYLVIO_004558	OG7
LpyrH10_02_7830 ⚠ Rrp44p homologue, putative	—	OG7 TCSYLVIO_002525 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_002525 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_007258	OG7
LpyrH10_24_0300 ⚠ mitochondrial exoribonuclease DSS-1, putative	—	OG7 TCSYLVIO_002525 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_002525 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_007258	OG7
LpyrH10_05_3640 ⚠ Cleavage and polyadenylation specificity fact	—	OG7 TCSYLVIO_005414 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_005414	OG7
LpyrH10_19_1650 ⚠ ATP-binding cassette protein subfamily F, mem	—	OG7 TCSYLVIO_006012 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006012	OG7
LpyrH10_34_0190 ⚠ ABC transporter protein, putative	—	OG7 TCSYLVIO_006012 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006012	OG7
LpyrH10_06_1830 ⚠ glycosyl hydrolase-like protein	—	OG7 TCSYLVIO_006140 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_006141 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006140 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006141	OG7
LpyrH10_27_0110 ⚠ protein kinase, putative	—	OG7 TCSYLVIO_005149 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_005149	OG7
LpyrH10_01_5510 ⚠ protein kinase, putative	—	OG7 TCSYLVIO_005149 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_005149	OG7
LpyrH10_03_4010 ⚠ protein kinase, putative	—	OG7 TCSYLVIO_005149 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_005149	OG7
LpyrH10_04_0600 ⚠ protein kinase, putative	—	OG7 TCSYLVIO_005149 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_005149	OG7
LpyrH10_11_0230 ⚠ protein kinase, putative	—	OG7 TCSYLVIO_005149 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_005149	OG7
LpyrH10_08_0420 ⚠ protein kinase-like protein	—	OG7 TCSYLVIO_005149 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_005149	OG7
LpyrH10_03_4000 ⚠ protein kinase, putative	—	OG7 TCSYLVIO_005149 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_005149	OG7
LpyrH10_27_0100 ⚠ MAP protein kinase, putative	—	OG7 TCSYLVIO_005149 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_005149	OG7
LpyrH10_15_1690 ⚠ Tyrosyl or methionyl-tRNA synthetase-like pro	—	OG7 TCSYLVIO_007258 ↔ TCSYLVIO_010624 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_010624	OG7
LpyrH10_09_0540 ⚠ dihydrouridine synthase domain protein-like p	—	OG7 TCSYLVIO_007258 ↔ TCSYLVIO_009102 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_009102	OG7
LpyrH10_05_1590 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_007258 ↔ TCSYLVIO_009102 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_009102	OG7
LpyrH10_04_5640 ⚠ Gtpase activator-like protein	—	OG7 TCSYLVIO_004558 ↔ TCSYLVIO_008881	OG7
LpyrH10_26_0710 ⚠ Hypothetical protein, conserved	—	OG7 TCSYLVIO_004558 ↔ TCSYLVIO_007065	OG7
LpyrH10_01_7930 ⚠ unspecified product	—	OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006188	OG7
LpyrH10_14_0070 ⚠ Hypothetical protein, conserved	—	OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006877 OG7 TCSYLVIO_006877 ↔ TCSYLVIO_007258	OG7
LpyrH10_17_1440 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006188	OG7
LpyrH10_04_1730 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006188	OG7
LpyrH10_14_0080 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006877 OG7 TCSYLVIO_006877 ↔ TCSYLVIO_007258	OG7
LpyrH10_12_0680 ⚠ dihydrouridine synthase (Dus), putative	—	OG7 TCSYLVIO_007258 ↔ TCSYLVIO_009102 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_009102	OG7
LpyrH10_01_6640 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006188	OG7

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