TRSC58_02283

DNA-directed RNA polymerases II

Trypanosoma rangeli SC58 OG6: OG6_101049 OG7: OG7_0005341 61 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 61 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
TRSC58_03091 ⚠ DNA-directed RNA polymerase I/III subunit	—	OG6 Tb927.10.13320 ↔ Tb927.11.8890 OG7 LdBPK_180780.1 ↔ LdBPK_271450.1 OG7 Tb927.10.13320 ↔ Tb927.11.8890 OG7 Tb927.10.13320 ↔ Tb927.11.2200	Both
TRSC58_05954 ⚠ DNA-directed RNA polymerase subunit	—	OG6 LdBPK_180780.1 ↔ LdBPK_340940.1 OG6 Tb927.10.13320 ↔ Tb927.4.3510 OG7 LdBPK_180780.1 ↔ LdBPK_340940.1 OG7 Tb927.10.13320 ↔ Tb927.11.200 +1 more	Both
TRSC58_00648 ⚠ hypothetical protein	—	OG6 Tb927.10.13320 ↔ Tb927.11.200 OG7 LdBPK_180780.1 ↔ LdBPK_340940.1 OG7 Tb927.10.13320 ↔ Tb927.11.200 OG7 Tb927.10.13320 ↔ Tb927.4.3510	Both
TRSC58_02462 ⚠ hypothetical protein	—	OG6 LdBPK_180780.1 ↔ LdBPK_340940.1 OG6 Tb927.10.13320 ↔ Tb927.4.3510 OG7 LdBPK_180780.1 ↔ LdBPK_340940.1 OG7 Tb927.10.13320 ↔ Tb927.11.200 +1 more	Both
TRSC58_03835 ⚠ hypothetical protein	—	OG6 TCSYLVIO_001614 ↔ TCSYLVIO_006204 OG7 TCSYLVIO_001614 ↔ TCSYLVIO_006204	Both
TRSC58_03397 ⚠ hypothetical protein	—	OG7 LdBPK_180780.1 ↔ LdBPK_303630.1	OG7
TRSC58_03695 ⚠ hypothetical protein	—	OG7 LdBPK_180780.1 ↔ LdBPK_303630.1	OG7
TRSC58_05047 ⚠ hypothetical protein	—	OG7 LdBPK_180780.1 ↔ LdBPK_323840.1	OG7
TRSC58_05977 ⚠ arginase	—	OG7 LdBPK_180780.1 ↔ LdBPK_351490.1	OG7
TRSC58_02842 ⚠ hypothetical protein	—	OG7 LdBPK_180780.1 ↔ LdBPK_320890.1	OG7
TRSC58_02174 ⚠ hypothetical protein	—	OG7 LdBPK_180780.1 ↔ LdBPK_303630.1	OG7
TRSC58_05282 ⚠ hypothetical protein	—	OG6 Tb927.1.1170 ↔ Tb927.10.13320 OG7 Tb927.1.1170 ↔ Tb927.10.13320	Both
TRSC58_06693 ⚠ histone H2A	—	OG7 Tb927.10.13310 ↔ Tb927.7.6360 OG7 Tb927.10.13320 ↔ Tb927.7.6360	OG7
TRSC58_04117 ⚠ DNA-directed RNA polymerase II subunit 3	—	OG6 Tb927.10.13320 ↔ Tb927.3.5500 OG7 Tb927.10.13310 ↔ Tb927.10.15370 OG7 Tb927.10.13320 ↔ Tb927.10.15370 OG7 Tb927.10.13320 ↔ Tb927.3.5500	Both
TRSC58_04916 ⚠ histone H3	—	OG6 Tb927.10.13320 ↔ Tb927.10.15350 OG7 Tb927.10.13310 ↔ Tb927.10.15350 OG7 Tb927.10.13320 ↔ Tb927.10.15350	Both
TRSC58_03426 ⚠ DNA-directed RNA polymerase	—	OG6 Tb927.10.13320 ↔ Tb927.11.10420 OG7 Tb927.10.13320 ↔ Tb927.11.7280 OG7 Tb927.10.13310 ↔ Tb927.11.10420 OG7 Tb927.10.13320 ↔ Tb927.11.10420	Both
TRSC58_02398 ⚠ DNA-directed RNA polymerase III largest subun	—	OG6 Tb927.10.13320 ↔ Tb927.4.5020 OG7 Tb927.10.13320 ↔ Tb927.4.5020 OG7 Tb927.10.13310 ↔ Tb927.8.5090 OG7 Tb927.10.13320 ↔ Tb927.8.5090	Both
TRSC58_04584 ⚠ DNA-directed RNA polymerase subunit	—	OG6 Tb927.10.13320 ↔ Tb927.3.1250 OG7 Tb927.10.13320 ↔ Tb927.3.1250	Both
TRSC58_02083 ⚠ hypothetical protein	—	OG7 LdBPK_180780.1 ↔ LdBPK_303630.1	OG7
TRSC58_05417 ⚠ RNA polymerase III C11 subunit	—	OG7 Tb927.10.13320 ↔ Tb927.11.7280 OG7 Tb927.10.13310 ↔ Tb927.11.10420 OG7 Tb927.10.13320 ↔ Tb927.11.10420	OG7
TRSC58_06890 ⚠ hypothetical protein	—	OG7 TCSYLVIO_006204 ↔ TCSYLVIO_009417	OG7
TRSC58_06398 ⚠ histone H2A	—	OG7 Tb927.10.13310 ↔ Tb927.7.6360 OG7 Tb927.10.13320 ↔ Tb927.7.6360	OG7
TRSC58_05499 ⚠ histone H3 variant	—	OG7 Tb927.10.13310 ↔ Tb927.10.15350 OG7 Tb927.10.13320 ↔ Tb927.10.15350	OG7
TRSC58_04266 ⚠ DNA-directed RNA polymerase III subunit	—	OG7 Tb927.10.13320 ↔ Tb927.11.14490	OG7
TRSC58_00976 ⚠ histone H2A	—	OG7 Tb927.10.13310 ↔ Tb927.7.6360 OG7 Tb927.10.13320 ↔ Tb927.7.6360	OG7
TRSC58_01150 ⚠ histone H2A	—	OG7 Tb927.10.13310 ↔ Tb927.7.6360 OG7 Tb927.10.13320 ↔ Tb927.7.6360	OG7
TRSC58_06361 ⚠ hypothetical protein	—	OG7 TCSYLVIO_006204 ↔ TCSYLVIO_009417	OG7
TRSC58_06424 ⚠ retrotransposon hot spot (RHS) protein	—	OG7 TCSYLVIO_006204 ↔ TCSYLVIO_009417	OG7
TRSC58_07003 ⚠ hypothetical protein	—	OG7 TCSYLVIO_006204 ↔ TCSYLVIO_009417	OG7
TRSC58_01499 ⚠ hypothetical protein	—	OG7 TCSYLVIO_006204 ↔ TCSYLVIO_009417	OG7
TRSC58_07193 ⚠ hypothetical protein	—	OG7 TCSYLVIO_006204 ↔ TCSYLVIO_009417	OG7
TRSC58_07112 ⚠ hypothetical protein	—	OG7 TCSYLVIO_006204 ↔ TCSYLVIO_009417	OG7
TRSC58_05081 ⚠ zinc finger-domain protein	—	OG6 LdBPK_180780.1 ↔ LdBPK_303630.1 OG7 LdBPK_180780.1 ↔ LdBPK_303630.1	Both
TRSC58_03964 ⚠ histone H3	—	OG6 Tb927.10.13320 ↔ Tb927.10.15350 OG7 Tb927.10.13310 ↔ Tb927.10.15350 OG7 Tb927.10.13320 ↔ Tb927.10.15350	Both
TRSC58_06679 ⚠ kinetoplastid membrane protein KMP-11	—	OG6 LdBPK_180780.1 ↔ LdBPK_352260.1 OG7 LdBPK_180780.1 ↔ LdBPK_352260.1	Both
TRSC58_01820 ⚠ kinetoplastid membrane protein KMP-11	—	OG6 LdBPK_180780.1 ↔ LdBPK_352260.1 OG7 LdBPK_180780.1 ↔ LdBPK_352260.1	Both
TRSC58_02226 ⚠ kinetoplastid membrane protein KMP-11	—	OG6 LdBPK_180780.1 ↔ LdBPK_352260.1 OG7 LdBPK_180780.1 ↔ LdBPK_352260.1	Both
TRSC58_02146 ⚠ hypothetical protein	—	OG6 LdBPK_180780.1 ↔ LdBPK_272430.1 OG7 LdBPK_180780.1 ↔ LdBPK_272430.1	Both
TRSC58_06460 ⚠ kinetoplastid membrane protein KMP-11	—	OG6 LdBPK_180780.1 ↔ LdBPK_352260.1 OG7 LdBPK_180780.1 ↔ LdBPK_352260.1	Both
TRSC58_05867 ⚠ hypothetical protein	—	OG6 LdBPK_180780.1 ↔ LdBPK_340730.1 OG7 LdBPK_180780.1 ↔ LdBPK_340730.1	Both
TRSC58_04013 ⚠ hypothetical protein	—	OG6 TCSYLVIO_005513 ↔ TCSYLVIO_006204 OG7 TCSYLVIO_005513 ↔ TCSYLVIO_006204	Both
TRSC58_05655 ⚠ hypothetical protein	—	OG6 TCSYLVIO_002508 ↔ TCSYLVIO_006204 OG7 TCSYLVIO_002508 ↔ TCSYLVIO_006204	Both
TRSC58_00931 ⚠ hypothetical protein	—	OG6 LdBPK_140390.1 ↔ LdBPK_180780.1 OG7 LdBPK_140390.1 ↔ LdBPK_180780.1	Both
TRSC58_01876 ⚠ DNA-directed RNA polymerase II	—	OG6 Tb927.10.13310 ↔ Tb927.10.13320 OG7 Tb927.10.13310 ↔ Tb927.10.13320	Both
TRSC58_04384 ⚠ hypothetical protein	—	OG6 Tb927.10.13320 ↔ Tb927.4.3810 OG7 Tb927.10.13320 ↔ Tb927.11.630 OG7 Tb927.10.13320 ↔ Tb927.4.3810	Both
TRSC58_01321 ⚠ RNA polymerase-like protein	—	OG6 Tb927.10.13320 ↔ Tb927.11.14490 OG7 Tb927.10.13320 ↔ Tb927.11.14490	Both
TRSC58_04151 ⚠ histone H3	—	OG6 Tb927.10.13320 ↔ Tb927.10.15350 OG7 Tb927.10.13310 ↔ Tb927.10.15350 OG7 Tb927.10.13320 ↔ Tb927.10.15350	Both
TRSC58_05447 ⚠ DNA-directed RNA polymerase II subunit RPB1	—	OG6 Tb927.10.13320 ↔ Tb927.4.5020 OG7 Tb927.10.13320 ↔ Tb927.4.5020 OG7 Tb927.10.13310 ↔ Tb927.8.5090 OG7 Tb927.10.13320 ↔ Tb927.8.5090	Both
TRSC58_05975 ⚠ hypothetical protein	—	OG6 Tb927.10.13320 ↔ Tb927.3.5270 OG7 Tb927.10.13320 ↔ Tb927.3.5270	Both
TRSC58_07064 ⚠ histone H3	—	OG6 Tb927.10.13320 ↔ Tb927.10.15350 OG7 Tb927.10.13310 ↔ Tb927.10.15350 OG7 Tb927.10.13320 ↔ Tb927.10.15350	Both

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