TRSC58_05447

DNA-directed RNA polymerase II subunit RPB1
Trypanosoma rangeli SC58 OG6: OG6_100210 OG7: OG7_0001854 176 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 176 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TRSC58_02623 ⚠
DNA-directed RNA polymerase, alpha subunit
— +2 more Both
TRSC58_02390 ⚠
acetyl-CoA carboxylase
— Both
TRSC58_06238 ⚠
phosphoribosylpyrophosphate synthetase
— Both
TRSC58_06401 ⚠
acetyl-CoA carboxylase
— Both
TRSC58_04952 ⚠
ribose-phosphate pyrophosphokinase
— Both
TRSC58_02439 ⚠
hypothetical protein
— Both
TRSC58_04117 ⚠
DNA-directed RNA polymerase II subunit 3
— +1 more Both
TRSC58_04384 ⚠
hypothetical protein
— +4 more Both
TRSC58_05044 ⚠
DNA-directed RNA polymerase II subunit 2
— +4 more Both
TRSC58_03682 ⚠
RNA polymerase I second largest subunit
— +1 more OG7
TRSC58_04392 ⚠
hypothetical protein
— OG7
TRSC58_02929 ⚠
phosphoribosylpyrophosphate synthetase
— OG7
TRSC58_06561 ⚠
phosphatidylinositol kinase related TOR1
— OG7
TRSC58_01360 ⚠
hypothetical protein
— OG7
TRSC58_07107 ⚠
hypothetical protein
— OG7
TRSC58_02036 ⚠
PAB-dependent poly(A)-specific ribonuclease s
— OG7
TRSC58_01748 ⚠
hypothetical protein
— OG7
TRSC58_01855 ⚠
hypothetical protein
— OG7
TRSC58_06477 ⚠
hypothetical protein
— OG7
TRSC58_00444 ⚠
hypothetical protein
— OG7
TRSC58_01683 ⚠
neurobeachin/beige protein
— OG7
TRSC58_03372 ⚠
hypothetical protein
— OG7
TRSC58_06676 ⚠
phosphatidylinositol kinase related TOR2
— OG7
TRSC58_01082 ⚠
hypothetical protein
— OG7
TRSC58_02335 ⚠
hypothetical protein
— OG7
TRSC58_00572 ⚠
hypothetical protein
— OG7
TRSC58_01454 ⚠
hypothetical protein
— OG7
TRSC58_05403 ⚠
dihydrolipoamide dehydrogenase
— OG7
TRSC58_00692 ⚠
hypothetical protein
— OG7
TRSC58_05083 ⚠
hypothetical protein
— OG7
TRSC58_06198 ⚠
hypothetical protein
— OG7
TRSC58_03217 ⚠
DNA replication licensing factor
— OG7
TRSC58_05274 ⚠
hypothetical protein
— OG7
TRSC58_01606 ⚠
pumilio-repeat, RNA-binding protein
— OG7
TRSC58_06169 ⚠
adenylate kinase
— OG7
TRSC58_02627 ⚠
hypothetical protein
— OG7
TRSC58_01689 ⚠
hypothetical protein
— OG7
TRSC58_06491 ⚠
phosphatidylinositol kinase related ATR
— OG7
TRSC58_06496 ⚠
small subunit ribosomal protein S27Ae
— OG7
TRSC58_03495 ⚠
protein phosphatase 2C
— OG7
TRSC58_06663 ⚠
hypothetical protein
— OG7
TRSC58_04515 ⚠
DNA replication factor
— OG7
TRSC58_01028 ⚠
minichromosome maintenance (MCM) complex subu
— OG7
TRSC58_06527 ⚠
phosphatidylinositol kinase related protein A
— OG7
TRSC58_01331 ⚠
hypothetical protein
— OG7
TRSC58_02446 ⚠
hypothetical protein
— OG7
TRSC58_03672 ⚠
hypothetical protein
— OG7
TRSC58_06581 ⚠
hypothetical protein
— OG7
TRSC58_01601 ⚠
protein phosphatase 2C
— OG7
TRSC58_06093 ⚠
phosphatidylinositol kinase related TOR-like
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.