TRSC58_03682

RNA polymerase I second largest subunit
Trypanosoma rangeli SC58 OG6: OG6_102249 OG7: OG7_0001821 175 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 175 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TRSC58_04485 ⚠
hypothetical protein
— +1 more OG7
TRSC58_00903 ⚠
ribosomal rRNA processing protein 40
— Both
TRSC58_04117 ⚠
DNA-directed RNA polymerase II subunit 3
— OG7
TRSC58_04319 ⚠
dihydrolipoamide dehydrogenase
— Both
TRSC58_02623 ⚠
DNA-directed RNA polymerase, alpha subunit
— OG7
TRSC58_03091 ⚠
DNA-directed RNA polymerase I/III subunit
— OG7
TRSC58_05447 ⚠
DNA-directed RNA polymerase II subunit RPB1
— +1 more OG7
TRSC58_05403 ⚠
dihydrolipoamide dehydrogenase
— OG7
TRSC58_02398 ⚠
DNA-directed RNA polymerase III largest subun
— +1 more OG7
TRSC58_02513 ⚠
DNA-directed RNA polymerase I largest subunit
— +3 more Both
TRSC58_04242 ⚠
DNA-directed RNA polymerase I largest subunit
— +3 more Both
TRSC58_04124 ⚠
exosome component CSL4
— Both
TRSC58_04392 ⚠
hypothetical protein
— OG7
TRSC58_06439 ⚠
phosphatidylinositol 3-kinase
— OG7
TRSC58_03362 ⚠
minichromosome maintenance (MCM) complex subu
— OG7
TRSC58_00787 ⚠
beta-adaptin
— OG7
TRSC58_03017 ⚠
phosphatase 2C
— OG7
TRSC58_00063 ⚠
protein phosphatase 2C
— OG7
TRSC58_02620 ⚠
minichromosome maintenance (MCM) complex subu
— OG7
TRSC58_02029 ⚠
hypothetical protein
— OG7
TRSC58_04732 ⚠
cullin 2
— OG7
TRSC58_06491 ⚠
phosphatidylinositol kinase related ATR
— OG7
TRSC58_06496 ⚠
small subunit ribosomal protein S27Ae
— OG7
TRSC58_03495 ⚠
protein phosphatase 2C
— OG7
TRSC58_04515 ⚠
DNA replication factor
— OG7
TRSC58_01028 ⚠
minichromosome maintenance (MCM) complex subu
— OG7
TRSC58_01601 ⚠
protein phosphatase 2C
— OG7
TRSC58_01693 ⚠
minichromosome maintenance (MCM) complex subu
— OG7
TRSC58_06527 ⚠
phosphatidylinositol kinase related protein A
— OG7
TRSC58_03672 ⚠
hypothetical protein
— OG7
TRSC58_01331 ⚠
hypothetical protein
— OG7
TRSC58_03217 ⚠
DNA replication licensing factor
— OG7
TRSC58_00692 ⚠
hypothetical protein
— OG7
TRSC58_00572 ⚠
hypothetical protein
— OG7
TRSC58_02335 ⚠
hypothetical protein
— OG7
TRSC58_06676 ⚠
phosphatidylinositol kinase related TOR2
— OG7
TRSC58_03372 ⚠
hypothetical protein
— OG7
TRSC58_06477 ⚠
hypothetical protein
— OG7
TRSC58_07107 ⚠
hypothetical protein
— OG7
TRSC58_06561 ⚠
phosphatidylinositol kinase related TOR1
— OG7
TRSC58_05889 ⚠
protein phosphatase
— OG7
TRSC58_06345 ⚠
minichromosome maintenance (MCM) complex subu
— OG7
TRSC58_06727 ⚠
hypothetical protein
— OG7
TRSC58_01689 ⚠
hypothetical protein
— OG7
TRSC58_04374 ⚠
exosome-associated protein 4
— OG7
TRSC58_05417 ⚠
RNA polymerase III C11 subunit
— OG7
TRSC58_03839 ⚠
ribosomal rRNA processing protein 41B
— OG7
TRSC58_04182 ⚠
DNA-direcetd RNA polymerase II, subunit 9
— OG7
TRSC58_07010 ⚠
RNA helicase
— OG7
TRSC58_05988 ⚠
DNA polymerase theta (helicase domain only)
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.