TRSC58_02438

malate dehydrogenase
Trypanosoma rangeli SC58 OG6: OG6_101212 OG7: OG7_0004751 59 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 59 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TRSC58_01873 ⚠
spermidine synthase
— Both
TRSC58_07168 ⚠
hypothetical protein
— OG7
TRSC58_02403 ⚠
aminoacylase
— Both
TRSC58_04010 ⚠
Oligopeptidase B
— Both
TRSC58_06861 ⚠
amidohydrolase
— Both
TRSC58_00793 ⚠
oligopeptidase B-like protein
— Both
TRSC58_00139 ⚠
cytochrome-B5 reductase
— OG7
TRSC58_02096 ⚠
hypothetical protein
— OG7
TRSC58_05530 ⚠
NADH-cytochrome B5 reductase
— OG7
TRSC58_00486 ⚠
D-alanyl-glycyl endopeptidase-like protein
— OG7
TRSC58_03053 ⚠
reductase
— OG7
TRSC58_03866 ⚠
trypanothione synthetase
— OG7
TRSC58_05283 ⚠
chaperonin HSP60/CNP60
— OG7
TRSC58_04656 ⚠
NADH-cytochrome B5 reductase
— OG7
TRSC58_00700 ⚠
RuvB-like DNA helicase
— OG7
TRSC58_02884 ⚠
hypothetical protein
— OG7
TRSC58_05892 ⚠
amidohydrolase
— Both
TRSC58_00885 ⚠
hypothetical protein
— OG7
TRSC58_00279 ⚠
hypothetical protein
— OG7
TRSC58_02481 ⚠
hypothetical protein
— OG7
TRSC58_05371 ⚠
prolyl oligopeptidase
— OG7
TRSC58_07173 ⚠
hypothetical protein
— OG7
TRSC58_05012 ⚠
prolyl oligopeptidase
— OG7
TRSC58_04112 ⚠
ATP-dependent DEAD/H RNA helicase
— OG7
TRSC58_04008 ⚠
eukaryotic initiation factor 4a
— OG7
TRSC58_05054 ⚠
ATP-dependent DEAD/H RNA helicase
— OG7
TRSC58_05574 ⚠
serine/threonine protein kinase
— OG7
TRSC58_02161 ⚠
serine/threonine protein phosphatase
— OG7
TRSC58_05159 ⚠
ecotin
— OG7
TRSC58_01503 ⚠
ecotin
— OG7
TRSC58_03469 ⚠
triosephosphate isomerase
— Both
TRSC58_01953
hypothetical protein
— OG6
TRSC58_00152 ⚠
deoxyribose-phosphate aldolase
— Both
TRSC58_04086 ⚠
hypothetical protein
— Both
TRSC58_01001 ⚠
hypothetical protein
— Both
TRSC58_05781 ⚠
inosine-adenosine-guanosine-nucleoside hydrol
— Both
TRSC58_01051 ⚠
2,3-bisphosphoglycerate-independent phosphogl
— Both
TRSC58_03675 ⚠
pyridoxal kinase
— Both
TRSC58_02001 ⚠
succinyl-CoA ligase [GDP-forming] beta-chain
— Both
TRSC58_06968 ⚠
succinyl-CoA ligase [GDP-forming] beta-chain
— Both
TRSC58_04016 ⚠
chaperonin Hsp60 mitochondrial precursor
— Both
TRSC58_01390 ⚠
chaperonin GroEL
— Both
TRSC58_03364 ⚠
NADH-cytochrome B5 reductase
— Both
TRSC58_04012 ⚠
adenine phosphoribosyltransferase
— Both
TRSC58_02778 ⚠
threonine synthase
— Both
TRSC58_02517 ⚠
trypanothione reductase
— Both
TRSC58_04835 ⚠
chaperonin GroEL
— Both
TRSC58_06888 ⚠
cytosolic malate dehydrogenase
— Both
TRSC58_01995 ⚠
trypanothione synthetase
— Both
TRSC58_00688 ⚠
adenine phosphoribosyltransferase
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.