TRSC58_02517

trypanothione reductase

Trypanosoma rangeli SC58 OG6: OG6_101659 OG7: OG7_0001626 51 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 51 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
TRSC58_01120 ⚠ hypothetical protein	—	OG7 TCSYLVIO_003496 ↔ TCSYLVIO_004807	OG7
TRSC58_04010 ⚠ Oligopeptidase B	—	OG6 TCSYLVIO_004807 ↔ TCSYLVIO_006546 OG7 TCSYLVIO_004807 ↔ TCSYLVIO_006546	Both
TRSC58_06861 ⚠ amidohydrolase	—	OG6 TCSYLVIO_004807 ↔ TCSYLVIO_008414 OG7 TCSYLVIO_004807 ↔ TCSYLVIO_008414	Both
TRSC58_00793 ⚠ oligopeptidase B-like protein	—	OG6 TCSYLVIO_004807 ↔ TCSYLVIO_006546 OG7 TCSYLVIO_004807 ↔ TCSYLVIO_006546	Both
TRSC58_03603 ⚠ RuvB-like DNA helicase	—	OG6 TCSYLVIO_003846 ↔ TCSYLVIO_004807 OG7 TCSYLVIO_003846 ↔ TCSYLVIO_004807	Both
TRSC58_00045 ⚠ TPR-repeat protein	—	OG6 TCSYLVIO_003496 ↔ TCSYLVIO_004807 OG7 TCSYLVIO_003496 ↔ TCSYLVIO_004807	Both
TRSC58_02438 ⚠ malate dehydrogenase	—	OG6 TCSYLVIO_004390 ↔ TCSYLVIO_004807 OG7 TCSYLVIO_004390 ↔ TCSYLVIO_004807	Both
TRSC58_00700 ⚠ RuvB-like DNA helicase	—	OG7 TCSYLVIO_003846 ↔ TCSYLVIO_004807	OG7
TRSC58_03544 ⚠ malate dehydrogenase	—	OG7 TCSYLVIO_004390 ↔ TCSYLVIO_004807	OG7
TRSC58_03342 ⚠ glycosomal malate dehydrogenase	—	OG7 TCSYLVIO_004390 ↔ TCSYLVIO_004807	OG7
TRSC58_06309 ⚠ hypothetical protein	—	OG7 TCSYLVIO_003496 ↔ TCSYLVIO_004807	OG7
TRSC58_02091 ⚠ stress-induced protein sti1	—	OG7 TCSYLVIO_003496 ↔ TCSYLVIO_004807	OG7
TRSC58_02773 ⚠ hypothetical protein	—	OG7 TCSYLVIO_003496 ↔ TCSYLVIO_004807	OG7
TRSC58_02403 ⚠ aminoacylase	—	OG6 TCSYLVIO_004807 ↔ TCSYLVIO_008414 OG7 TCSYLVIO_004807 ↔ TCSYLVIO_008414	Both
TRSC58_06146 ⚠ hypothetical protein	—	OG7 TCSYLVIO_003496 ↔ TCSYLVIO_004807	OG7
TRSC58_04486 ⚠ hypothetical protein	—	OG7 TCSYLVIO_004807 ↔ TCSYLVIO_005601	OG7
TRSC58_02884 ⚠ hypothetical protein	—	OG7 TCSYLVIO_004807 ↔ TCSYLVIO_009943	OG7
TRSC58_07168 ⚠ hypothetical protein	—	OG7 TCSYLVIO_004807 ↔ TCSYLVIO_009943	OG7
TRSC58_00885 ⚠ hypothetical protein	—	OG7 TCSYLVIO_004807 ↔ TCSYLVIO_009943	OG7
TRSC58_00279 ⚠ hypothetical protein	—	OG7 TCSYLVIO_004807 ↔ TCSYLVIO_009943	OG7
TRSC58_02481 ⚠ hypothetical protein	—	OG7 TCSYLVIO_004807 ↔ TCSYLVIO_009943	OG7
TRSC58_05371 ⚠ prolyl oligopeptidase	—	OG7 TCSYLVIO_004807 ↔ TCSYLVIO_006546	OG7
TRSC58_07173 ⚠ hypothetical protein	—	OG7 TCSYLVIO_004807 ↔ TCSYLVIO_009943	OG7
TRSC58_05012 ⚠ prolyl oligopeptidase	—	OG7 TCSYLVIO_004807 ↔ TCSYLVIO_006546	OG7
TRSC58_05502 ⚠ hypothetical protein	—	OG7 Tb927.10.10390 ↔ Tb927.3.4750	OG7
TRSC58_01014 ⚠ cytosol alanyl aminopeptidase	—	OG7 Tb927.10.10390 ↔ Tb927.3.4750	OG7
TRSC58_07150 ⚠ enolase	—	OG6 Tb927.10.10390 ↔ Tb927.10.2890 OG7 Tb927.10.10390 ↔ Tb927.10.2890	Both
TRSC58_01304 ⚠ hypothetical protein	—	OG6 Tb927.1.1240 ↔ Tb927.10.10390 OG7 Tb927.1.1240 ↔ Tb927.10.10390	Both
TRSC58_06784 ⚠ cytidine triphosphate synthase	—	OG6 Tb927.1.1240 ↔ Tb927.10.10390 OG7 Tb927.1.1240 ↔ Tb927.10.10390	Both
TRSC58_04086 ⚠ hypothetical protein	—	OG6 TCSYLVIO_003157 ↔ TCSYLVIO_004807 OG7 TCSYLVIO_003157 ↔ TCSYLVIO_004807	Both
TRSC58_01001 ⚠ hypothetical protein	—	OG6 TCSYLVIO_003157 ↔ TCSYLVIO_004807 OG7 TCSYLVIO_003157 ↔ TCSYLVIO_004807	Both
TRSC58_02154 6-phosphogluconate dehydrogenase, decarboxyla	—	OG6 Tb927.10.10390 ↔ Tb927.9.12110 OG7 Tb927.10.10390 ↔ Tb927.9.12110	Both
TRSC58_06047 ⚠ fumarate hydratase	—	OG6 Tb927.10.10390 ↔ Tb927.3.4500 OG7 Tb927.10.10390 ↔ Tb927.3.4500	Both
TRSC58_00190 3-hydroxy-3-methylglutaryl-CoA reductase	—	OG6 Tb927.10.10390 ↔ Tb927.6.4540 OG7 Tb927.10.10390 ↔ Tb927.6.4540	Both
TRSC58_01180 ⚠ nucleoside diphosphate kinase	—	OG6 Tb927.10.10390 ↔ Tb927.11.16130 OG7 Tb927.10.10390 ↔ Tb927.11.16130	Both
TRSC58_01327 ⚠ aminopeptidase	—	OG6 Tb927.10.10390 ↔ Tb927.3.4750 OG7 Tb927.10.10390 ↔ Tb927.3.4750	Both
TRSC58_04533 ⚠ fumarate hydratase	—	OG6 Tb927.10.10390 ↔ Tb927.3.4500 OG7 Tb927.10.10390 ↔ Tb927.3.4500	Both
TRSC58_02197 guanine deaminase	—	OG6 Tb927.10.10390 ↔ Tb927.5.4560 OG7 Tb927.10.10390 ↔ Tb927.5.4560	Both
TRSC58_04698 glycerol kinase, glycosomal	—	OG6 Tb927.10.10390 ↔ Tb927.9.12570 OG7 Tb927.10.10390 ↔ Tb927.9.12570	Both
TRSC58_03443 ⚠ cytidine triphosphate synthase	—	OG6 Tb927.1.1240 ↔ Tb927.10.10390 OG7 Tb927.1.1240 ↔ Tb927.10.10390	Both
TRSC58_02233 pteridine reductase	—	OG6 Tb927.10.10390 ↔ Tb927.8.2210 OG7 Tb927.10.10390 ↔ Tb927.8.2210	Both
TRSC58_01740 aminopeptidase P	—	OG6 Tb927.10.10390 ↔ Tb927.9.13490 OG7 Tb927.10.10390 ↔ Tb927.9.13490	Both
TRSC58_06599 ⚠ enolase	—	OG6 Tb927.10.10390 ↔ Tb927.10.2890 OG7 Tb927.10.10390 ↔ Tb927.10.2890	Both
TRSC58_02143 ⚠ nucleoside diphosphate kinase	—	OG6 Tb927.10.10390 ↔ Tb927.11.16130 OG7 Tb927.10.10390 ↔ Tb927.11.16130	Both
TRSC58_03736 kynureninase	—	OG6 Tb927.10.10390 ↔ Tb927.9.2010 OG7 Tb927.10.10390 ↔ Tb927.9.2010	Both
TRSC58_04280 S-adenosylmethionine synthetase	—	OG6 Tb927.10.10390 ↔ Tb927.6.4840 OG7 Tb927.10.10390 ↔ Tb927.6.4840	Both
TRSC58_03256 methylthioadenosine phosphorylase	—	OG6 Tb927.10.10390 ↔ Tb927.7.7040 OG7 Tb927.10.10390 ↔ Tb927.7.7040	Both
TRSC58_06350 ⚠ amidohydrolase	—	OG6 TCSYLVIO_004807 ↔ TCSYLVIO_008414 OG7 TCSYLVIO_004807 ↔ TCSYLVIO_008414	Both
TRSC58_01658 hypothetical protein	—	OG6 TCSYLVIO_004807 ↔ TCSYLVIO_008910 OG7 TCSYLVIO_004807 ↔ TCSYLVIO_008910	Both
TRSC58_05892 ⚠ amidohydrolase	—	OG6 TCSYLVIO_004807 ↔ TCSYLVIO_008414 OG7 TCSYLVIO_004807 ↔ TCSYLVIO_008414	Both

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