TRSC58_03603

RuvB-like DNA helicase

Trypanosoma rangeli SC58 OG6: OG6_101635 OG7: OG7_0003574 52 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 52 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
TRSC58_06167 ⚠ H/ACA ribonucleoprotein complex subunit 4	—	OG6 Tb927.10.170 ↔ Tb927.4.2000 OG6 TCSYLVIO_003846 ↔ TCSYLVIO_009376 OG6 LdBPK_212130.1 ↔ LdBPK_342440.1 OG7 TCSYLVIO_003846 ↔ TCSYLVIO_009376 +3 more	Both
TRSC58_00863 ⚠ centromere/microtubule binding protein cbf5	—	OG6 Tb927.10.170 ↔ Tb927.4.2000 OG6 TCSYLVIO_003846 ↔ TCSYLVIO_009376 OG6 LdBPK_212130.1 ↔ LdBPK_342440.1 OG7 TCSYLVIO_003846 ↔ TCSYLVIO_009376 +3 more	Both
TRSC58_00700 ⚠ RuvB-like DNA helicase	—	OG6 LdBPK_342440.1 ↔ LdBPK_343280.1 OG6 Tb927.4.1270 ↔ Tb927.4.2000 OG7 Tb927.4.1270 ↔ Tb927.4.2000 OG7 LdBPK_342440.1 ↔ LdBPK_343280.1	Both
TRSC58_00793 ⚠ oligopeptidase B-like protein	—	OG6 TCSYLVIO_003846 ↔ TCSYLVIO_006546 OG7 TCSYLVIO_003846 ↔ TCSYLVIO_006546	Both
TRSC58_05885 ⚠ cyclic nucleotide-binding protein	—	OG7 TCSYLVIO_003826 ↔ TCSYLVIO_003846	OG7
TRSC58_04992 ⚠ phenylalanyl-tRNA synthetase alpha chain	—	OG6 Tb927.11.14120 ↔ Tb927.4.2000 OG7 Tb927.11.14120 ↔ Tb927.4.2000 OG7 Tb927.11.14120 ↔ Tb927.4.1270	Both
TRSC58_02887 ⚠ carnitine O-palmitoyltransferase II	—	OG7 Tb927.11.2230 ↔ Tb927.4.2000 OG7 Tb927.11.2230 ↔ Tb927.4.1270	OG7
TRSC58_01783 ⚠ carnitine/choline acetyltransferase	—	OG7 Tb927.11.2230 ↔ Tb927.4.2000 OG7 Tb927.11.2230 ↔ Tb927.4.1270	OG7
TRSC58_02884 ⚠ hypothetical protein	—	OG7 TCSYLVIO_003846 ↔ TCSYLVIO_009943	OG7
TRSC58_07168 ⚠ hypothetical protein	—	OG7 TCSYLVIO_003846 ↔ TCSYLVIO_009943	OG7
TRSC58_06361 ⚠ hypothetical protein	—	OG7 TCSYLVIO_003846 ↔ TCSYLVIO_010221 OG7 TCSYLVIO_003846 ↔ TCSYLVIO_009314 OG7 TCSYLVIO_003046 ↔ TCSYLVIO_003846	OG7
TRSC58_06424 ⚠ retrotransposon hot spot (RHS) protein	—	OG7 TCSYLVIO_003846 ↔ TCSYLVIO_010221 OG7 TCSYLVIO_003846 ↔ TCSYLVIO_009314 OG7 TCSYLVIO_003046 ↔ TCSYLVIO_003846	OG7
TRSC58_03544 ⚠ malate dehydrogenase	—	OG7 TCSYLVIO_003846 ↔ TCSYLVIO_004390	OG7
TRSC58_00885 ⚠ hypothetical protein	—	OG7 TCSYLVIO_003846 ↔ TCSYLVIO_009943	OG7
TRSC58_00279 ⚠ hypothetical protein	—	OG7 TCSYLVIO_003846 ↔ TCSYLVIO_009943	OG7
TRSC58_07003 ⚠ hypothetical protein	—	OG7 TCSYLVIO_003846 ↔ TCSYLVIO_010221 OG7 TCSYLVIO_003846 ↔ TCSYLVIO_009314 OG7 TCSYLVIO_003046 ↔ TCSYLVIO_003846	OG7
TRSC58_03342 ⚠ glycosomal malate dehydrogenase	—	OG7 TCSYLVIO_003846 ↔ TCSYLVIO_004390	OG7
TRSC58_01499 ⚠ hypothetical protein	—	OG7 TCSYLVIO_003846 ↔ TCSYLVIO_010221 OG7 TCSYLVIO_003846 ↔ TCSYLVIO_009314 OG7 TCSYLVIO_003046 ↔ TCSYLVIO_003846	OG7
TRSC58_02481 ⚠ hypothetical protein	—	OG7 TCSYLVIO_003846 ↔ TCSYLVIO_009943	OG7
TRSC58_05371 ⚠ prolyl oligopeptidase	—	OG7 TCSYLVIO_003846 ↔ TCSYLVIO_006546	OG7
TRSC58_07193 ⚠ hypothetical protein	—	OG7 TCSYLVIO_003846 ↔ TCSYLVIO_010221 OG7 TCSYLVIO_003846 ↔ TCSYLVIO_009314 OG7 TCSYLVIO_003046 ↔ TCSYLVIO_003846	OG7
TRSC58_07173 ⚠ hypothetical protein	—	OG7 TCSYLVIO_003846 ↔ TCSYLVIO_009943	OG7
TRSC58_07112 ⚠ hypothetical protein	—	OG7 TCSYLVIO_003846 ↔ TCSYLVIO_010221 OG7 TCSYLVIO_003846 ↔ TCSYLVIO_009314 OG7 TCSYLVIO_003046 ↔ TCSYLVIO_003846	OG7
TRSC58_06890 ⚠ hypothetical protein	—	OG7 TCSYLVIO_003846 ↔ TCSYLVIO_010221 OG7 TCSYLVIO_003846 ↔ TCSYLVIO_009314 OG7 TCSYLVIO_003046 ↔ TCSYLVIO_003846	OG7
TRSC58_05012 ⚠ prolyl oligopeptidase	—	OG7 TCSYLVIO_003846 ↔ TCSYLVIO_006546	OG7
TRSC58_02920 ⚠ fibrillarin	—	OG7 Tb927.10.7500 ↔ Tb927.4.1270	OG7
TRSC58_03633 ⚠ protein kinase A regulatory subunit	—	OG7 TCSYLVIO_003826 ↔ TCSYLVIO_003846	OG7
TRSC58_00039 ⚠ hslvu complex proteolytic subunit	—	OG6 Tb927.11.10240 ↔ Tb927.4.2000 OG7 Tb927.11.10240 ↔ Tb927.4.2000 OG7 Tb927.11.10240 ↔ Tb927.4.1270	Both
TRSC58_00499 ⚠ hypothetical protein	—	OG6 Tb927.4.2000 ↔ Tb927.6.3610 OG7 Tb927.4.2000 ↔ Tb927.6.3610 OG7 Tb927.4.1270 ↔ Tb927.6.3610	Both
TRSC58_05291 ⚠ carnitine O-acetyltransferase	—	OG6 Tb927.11.2230 ↔ Tb927.4.2000 OG7 Tb927.11.2230 ↔ Tb927.4.2000 OG7 Tb927.11.2230 ↔ Tb927.4.1270	Both
TRSC58_03288 ⚠ carnitine O-acetyltransferase	—	OG6 Tb927.11.2230 ↔ Tb927.4.2000 OG7 Tb927.11.2230 ↔ Tb927.4.2000 OG7 Tb927.11.2230 ↔ Tb927.4.1270	Both
TRSC58_05872 ⚠ hypothetical protein	—	OG6 TCSYLVIO_003436 ↔ TCSYLVIO_003846 OG7 TCSYLVIO_003436 ↔ TCSYLVIO_003846	Both
TRSC58_03581 ⚠ fatty acyl CoA synthetase	—	OG6 TCSYLVIO_003436 ↔ TCSYLVIO_003846 OG7 TCSYLVIO_003436 ↔ TCSYLVIO_003846	Both
TRSC58_01059 ⚠ fatty acyl CoA syntetase 1	—	OG6 TCSYLVIO_003436 ↔ TCSYLVIO_003846 OG7 TCSYLVIO_003436 ↔ TCSYLVIO_003846	Both
TRSC58_00504 ⚠ fatty acyl CoA syntetase 1	—	OG6 TCSYLVIO_003436 ↔ TCSYLVIO_003846 OG7 TCSYLVIO_003436 ↔ TCSYLVIO_003846	Both
TRSC58_05627 ⚠ fatty acyl CoA synthetase 2	—	OG6 TCSYLVIO_003436 ↔ TCSYLVIO_003846 OG7 TCSYLVIO_003436 ↔ TCSYLVIO_003846	Both
TRSC58_07121 ⚠ fatty acyl CoA synthetase	—	OG6 TCSYLVIO_003436 ↔ TCSYLVIO_003846 OG7 TCSYLVIO_003436 ↔ TCSYLVIO_003846	Both
TRSC58_04086 ⚠ hypothetical protein	—	OG6 TCSYLVIO_003157 ↔ TCSYLVIO_003846 OG7 TCSYLVIO_003157 ↔ TCSYLVIO_003846	Both
TRSC58_01001 ⚠ hypothetical protein	—	OG6 TCSYLVIO_003157 ↔ TCSYLVIO_003846 OG7 TCSYLVIO_003157 ↔ TCSYLVIO_003846	Both
TRSC58_02871 ⚠ hypothetical protein	—	OG6 Tb927.4.2000 ↔ Tb927.7.5890 OG7 Tb927.4.2000 ↔ Tb927.7.5890 OG7 Tb927.4.1270 ↔ Tb927.7.5890	Both
TRSC58_06861 ⚠ amidohydrolase	—	OG6 TCSYLVIO_003846 ↔ TCSYLVIO_008414 OG7 TCSYLVIO_003846 ↔ TCSYLVIO_008414	Both
TRSC58_04704 ⚠ cysteinyl-tRNA synthetase	—	OG6 Tb927.4.2000 ↔ Tb927.6.950 OG7 Tb927.4.2000 ↔ Tb927.6.950 OG7 Tb927.4.1270 ↔ Tb927.6.950	Both
TRSC58_05631 ⚠ glutamate dehydrogenase	—	OG6 Tb927.4.2000 ↔ Tb927.9.5900 OG7 Tb927.4.2000 ↔ Tb927.9.5900 OG7 Tb927.4.1270 ↔ Tb927.9.5900	Both
TRSC58_06392 ⚠ hypothetical protein	—	OG6 Tb927.4.2000 ↔ Tb927.7.5290 OG7 Tb927.4.2000 ↔ Tb927.7.5290 OG7 Tb927.4.1270 ↔ Tb927.7.5290	Both
TRSC58_06350 ⚠ amidohydrolase	—	OG6 TCSYLVIO_003846 ↔ TCSYLVIO_008414 OG7 TCSYLVIO_003846 ↔ TCSYLVIO_008414	Both
TRSC58_03489 ⚠ dihydrolipoamide branched chain transacylase	—	OG6 TCSYLVIO_003846 ↔ TCSYLVIO_009880 OG7 TCSYLVIO_003846 ↔ TCSYLVIO_009880	Both
TRSC58_02438 ⚠ malate dehydrogenase	—	OG6 TCSYLVIO_003846 ↔ TCSYLVIO_004390 OG7 TCSYLVIO_003846 ↔ TCSYLVIO_004390	Both
TRSC58_01658 ⚠ hypothetical protein	—	OG6 TCSYLVIO_003846 ↔ TCSYLVIO_008910 OG7 TCSYLVIO_003846 ↔ TCSYLVIO_008910	Both
TRSC58_05892 ⚠ amidohydrolase	—	OG6 TCSYLVIO_003846 ↔ TCSYLVIO_008414 OG7 TCSYLVIO_003846 ↔ TCSYLVIO_008414	Both
TRSC58_02517 ⚠ trypanothione reductase	—	OG6 TCSYLVIO_003846 ↔ TCSYLVIO_004807 OG7 TCSYLVIO_003846 ↔ TCSYLVIO_004807	Both

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