TRSC58_02469

pyruvate kinase 2
Trypanosoma rangeli SC58 OG6: OG6_100258 OG7: OG7_0002165 184 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 184 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TRSC58_03555
acidocalcisomal pyrophosphatase
— Both
TRSC58_04993
hypothetical protein
— Both
TRSC58_03224 ⚠
calpain-like cysteine peptidase
— OG7
TRSC58_00117 ⚠
cAMP specific phosphodiesterase
— Both
TRSC58_01059 ⚠
fatty acyl CoA syntetase 1
— Both
TRSC58_06701 ⚠
glyceraldehyde 3-phosphate dehydrogenase
— Both
TRSC58_05200 ⚠
hypothetical protein
— Both
TRSC58_00504 ⚠
fatty acyl CoA syntetase 1
— Both
TRSC58_02813 ⚠
glutaminyl-tRNA synthetase
— Both
TRSC58_02197
guanine deaminase
— Both
TRSC58_06909 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— Both
TRSC58_06402 ⚠
hypothetical protein
— Both
TRSC58_04930 ⚠
NADH-dependent fumarate reductase
— Both
TRSC58_05627 ⚠
fatty acyl CoA synthetase 2
— Both
TRSC58_04716 ⚠
hypothetical protein
— Both
TRSC58_02928 ⚠
aminopeptidase
— Both
TRSC58_07121 ⚠
fatty acyl CoA synthetase
— Both
TRSC58_04369
isovaleryl-coA dehydrogenase
— Both
TRSC58_06554 ⚠
hypothetical protein
— Both
TRSC58_06452 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— Both
TRSC58_00593
adenylosuccinate synthetase
— Both
TRSC58_04280
S-adenosylmethionine synthetase
— Both
TRSC58_06364 ⚠
glyceraldehyde 3-phosphate dehydrogenase
— Both
TRSC58_00668 ⚠
glutaminyl-tRNA synthetase
— Both
TRSC58_02117
transketolase
— Both
TRSC58_00092 ⚠
hypothetical protein
— Both
TRSC58_03759 ⚠
dihydrofolate reductase-thymidylate synthase
— Both
TRSC58_03666
phosphomannomutase-like protein
— Both
TRSC58_01208
N-myristoyl transferase
— Both
TRSC58_06291
ubiquitin hydrolase
— Both
TRSC58_06350 ⚠
amidohydrolase
— Both
TRSC58_02525
hypothetical protein
— Both
TRSC58_02594
hypothetical protein
— Both
TRSC58_05892 ⚠
amidohydrolase
— Both
TRSC58_02403 ⚠
aminoacylase
— Both
TRSC58_06861 ⚠
amidohydrolase
— Both
TRSC58_05656
nicotinate phosphoribosyltransferase
— Both
TRSC58_05901
35 kDa cyclophilin
— OG6
TRSC58_03188 ⚠
transcription elongation factor-like protein
— Both
TRSC58_01227
glucose-6-phosphate isomerase, glycosomal
— Both
TRSC58_00152
deoxyribose-phosphate aldolase
— Both
TRSC58_06101 ⚠
MCAK-like kinesin
— OG7
TRSC58_06570 ⚠
kinesin family member 2/24
— OG7
TRSC58_04165 ⚠
MCAK-like kinesin
— OG7
TRSC58_04721 ⚠
hypothetical protein
— OG7
TRSC58_06191 ⚠
mitotic centromere-associated kinesin (MCAK)
— OG7
TRSC58_05649 ⚠
calpain cysteine peptidase
— OG7
TRSC58_02091 ⚠
stress-induced protein sti1
— OG7
TRSC58_02568
methylenetetrahydrofolate dehydrogenase-like
— OG7
TRSC58_01909 ⚠
elongation factor G2-like protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.