TRSC58_04454

leucyl-tRNA synthetase

Trypanosoma rangeli SC58 OG6: OG6_101014 OG7: OG7_0005523 115 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 115 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
TRSC58_03654 ⚠ isoleucyl-tRNA synthetase	—	OG6 Tb927.10.9190 ↔ Tb927.11.3730 OG6 TCSYLVIO_003028 ↔ TCSYLVIO_004705 OG7 Tb927.10.9190 ↔ Tb927.11.3730 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_004705	Both
TRSC58_07732 ⚠ leucyl-tRNA synthetase	—	OG6 Tb927.10.1500 ↔ Tb927.11.3730 OG6 TCSYLVIO_003028 ↔ TCSYLVIO_007991 OG7 Tb927.10.1500 ↔ Tb927.11.3730 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_007991	Both
TRSC58_04190 ⚠ hypothetical protein	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_003345 OG6 Tb927.11.3730 ↔ Tb927.6.4480 OG7 Tb927.11.3730 ↔ Tb927.6.4480 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_003345	Both
TRSC58_05241 ⚠ tryptophanyl-tRNA synthetase	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_010724 OG6 Tb927.11.3730 ↔ Tb927.3.5580 OG7 Tb927.11.3730 ↔ Tb927.3.5580 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_010724	Both
TRSC58_07059 ⚠ valyl-tRNA synthetase	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_003345 OG6 Tb927.11.3730 ↔ Tb927.6.4480 OG7 Tb927.11.3730 ↔ Tb927.6.4480 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_003345	Both
TRSC58_01178 ⚠ tyrosyl or methionyl-tRNA synthetase	—	OG7 Tb927.11.3730 ↔ Tb927.7.3620 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_010624	OG7
TRSC58_05705 ⚠ tryptophanyl-tRNA synthetase	—	OG7 Tb927.11.3730 ↔ Tb927.3.5580 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_010724	OG7
TRSC58_05475 ⚠ hypothetical protein	—	OG7 Tb927.11.3730 ↔ Tb927.7.3620 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_010624	OG7
TRSC58_02133 ⚠ glycyl-tRNA synthetase	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_009222 OG6 Tb927.11.3730 ↔ Tb927.11.9640 OG7 Tb927.11.3730 ↔ Tb927.11.9640 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_009222	Both
TRSC58_03936 ⚠ valyl-tRNA synthetase	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_003345 OG6 Tb927.11.3730 ↔ Tb927.6.4480 OG7 Tb927.11.3730 ↔ Tb927.6.4480 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_003345	Both
TRSC58_04730 ⚠ tyrosyl-tRNA synthetase	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_010624 OG6 Tb927.11.3730 ↔ Tb927.7.3620 OG7 Tb927.11.3730 ↔ Tb927.7.3620 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_010624	Both
TRSC58_02773 ⚠ hypothetical protein	—	OG7 TCSYLVIO_003028 ↔ TCSYLVIO_003496	OG7
TRSC58_05489 ⚠ delta-1-pyrroline-5-carboxylate dehydrogenase	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_004515 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_004515	Both
TRSC58_05116 ⚠ calreticulin	—	OG6 TCSYLVIO_002866 ↔ TCSYLVIO_003028 OG7 TCSYLVIO_002866 ↔ TCSYLVIO_003028	Both
TRSC58_05611 ⚠ hypothetical protein	—	OG6 TCSYLVIO_001161 ↔ TCSYLVIO_003028 OG7 TCSYLVIO_001161 ↔ TCSYLVIO_003028	Both
TRSC58_02774 ⚠ prolyl-tRNA synthetase	—	OG6 Tb927.10.12890 ↔ Tb927.11.3730 OG7 Tb927.10.12890 ↔ Tb927.11.3730	Both
TRSC58_05065 ⚠ glucosamine-fructose-6-phosphate aminotransfe	—	OG6 TCSYLVIO_001869 ↔ TCSYLVIO_003028 OG7 TCSYLVIO_001869 ↔ TCSYLVIO_003028	Both
TRSC58_06404 ⚠ hypothetical protein	—	OG6 TCSYLVIO_001255 ↔ TCSYLVIO_003028 OG7 TCSYLVIO_001255 ↔ TCSYLVIO_003028	Both
TRSC58_04099 ⚠ translation initiation factor IF-2	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_003028 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_003028	Both
TRSC58_04722 ⚠ hypothetical protein	—	OG6 TCSYLVIO_001255 ↔ TCSYLVIO_003028 OG7 TCSYLVIO_001255 ↔ TCSYLVIO_003028	Both
TRSC58_00610 ⚠ hypothetical protein	—	OG6 TCSYLVIO_001973 ↔ TCSYLVIO_003028 OG7 TCSYLVIO_001973 ↔ TCSYLVIO_003028	Both
TRSC58_03727 ⚠ alanyl-tRNA synthetase	—	OG6 TCSYLVIO_001889 ↔ TCSYLVIO_003028 OG7 TCSYLVIO_001889 ↔ TCSYLVIO_003028	Both
TRSC58_06650 ⚠ ribonuclease II-like protein	—	OG6 TCSYLVIO_002525 ↔ TCSYLVIO_003028 OG6 TCSYLVIO_002526 ↔ TCSYLVIO_003028 OG7 TCSYLVIO_002525 ↔ TCSYLVIO_003028 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_003028	Both
TRSC58_01090 ⚠ hypothetical protein	—	OG6 TCSYLVIO_000836 ↔ TCSYLVIO_003028 OG7 TCSYLVIO_000836 ↔ TCSYLVIO_003028	Both
TRSC58_03555 ⚠ acidocalcisomal pyrophosphatase	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_003028 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_003028	Both
TRSC58_04624 ⚠ RRP44p like proteinue	—	OG7 TCSYLVIO_002525 ↔ TCSYLVIO_003028 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_003028	OG7
TRSC58_00367 ⚠ mitochondrial exoribonuclease DSS-1	—	OG7 TCSYLVIO_002525 ↔ TCSYLVIO_003028 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_003028	OG7
TRSC58_02203 ⚠ hypothetical protein	—	OG7 TCSYLVIO_000834 ↔ TCSYLVIO_003028	OG7
TRSC58_05766 ⚠ translation initiation factor IF-2	—	OG7 TCSYLVIO_001768 ↔ TCSYLVIO_003028	OG7
TRSC58_04869 ⚠ hypothetical protein	—	OG7 TCSYLVIO_003028 ↔ TCSYLVIO_004998	OG7
TRSC58_05416 ⚠ rab6 GTPase activating protein	—	OG7 TCSYLVIO_003028 ↔ TCSYLVIO_004663	OG7
TRSC58_02059 ⚠ hypothetical protein	—	OG7 TCSYLVIO_003028 ↔ TCSYLVIO_009102	OG7
TRSC58_02755 ⚠ glycosyl hydrolase-like protein	—	OG7 TCSYLVIO_003028 ↔ TCSYLVIO_006140 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_006141	OG7
TRSC58_02091 ⚠ stress-induced protein sti1	—	OG7 TCSYLVIO_003028 ↔ TCSYLVIO_003496	OG7
TRSC58_07003 ⚠ hypothetical protein	—	OG7 TCSYLVIO_003028 ↔ TCSYLVIO_008932 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_010148	OG7
TRSC58_05012 ⚠ prolyl oligopeptidase	—	OG7 TCSYLVIO_003028 ↔ TCSYLVIO_006546	OG7
TRSC58_06146 ⚠ hypothetical protein	—	OG7 TCSYLVIO_003028 ↔ TCSYLVIO_003496	OG7
TRSC58_03077 ⚠ protein kinase	—	OG7 TCSYLVIO_003028 ↔ TCSYLVIO_005149	OG7
TRSC58_01120 ⚠ hypothetical protein	—	OG7 TCSYLVIO_003028 ↔ TCSYLVIO_003496	OG7
TRSC58_06890 ⚠ hypothetical protein	—	OG7 TCSYLVIO_003028 ↔ TCSYLVIO_008932 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_010148	OG7
TRSC58_07112 ⚠ hypothetical protein	—	OG7 TCSYLVIO_003028 ↔ TCSYLVIO_008932 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_010148	OG7
TRSC58_04263 ⚠ cleavage and polyadenylation specificity fact	—	OG7 TCSYLVIO_003028 ↔ TCSYLVIO_005414	OG7
TRSC58_06526 ⚠ hypothetical protein	—	OG7 TCSYLVIO_003028 ↔ TCSYLVIO_003124	OG7
TRSC58_07193 ⚠ hypothetical protein	—	OG7 TCSYLVIO_003028 ↔ TCSYLVIO_008932 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_010148	OG7
TRSC58_05371 ⚠ prolyl oligopeptidase	—	OG7 TCSYLVIO_003028 ↔ TCSYLVIO_006546	OG7
TRSC58_05583 ⚠ aspartyl-tRNA synthetase	—	OG7 TCSYLVIO_003028 ↔ TCSYLVIO_003867	OG7
TRSC58_01499 ⚠ hypothetical protein	—	OG7 TCSYLVIO_003028 ↔ TCSYLVIO_008932 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_010148	OG7
TRSC58_01959 ⚠ hypothetical protein	—	OG7 TCSYLVIO_003028 ↔ TCSYLVIO_003867	OG7
TRSC58_01725 ⚠ hypothetical protein	—	OG7 TCSYLVIO_003028 ↔ TCSYLVIO_005149	OG7
TRSC58_06309 ⚠ hypothetical protein	—	OG7 TCSYLVIO_003028 ↔ TCSYLVIO_003496	OG7

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