TRSC58_06787

D-isomer specific 2-hydroxyacid dehydrogenase-protein

Trypanosoma rangeli SC58 OG6: OG6_103299 OG7: OG7_0001275 73 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 73 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
TRSC58_04836 ⚠ hypothetical protein	—	OG6 TCSYLVIO_001163 ↔ TCSYLVIO_003910 OG6 TCSYLVIO_001163 ↔ TCSYLVIO_003911 OG6 TCSYLVIO_001163 ↔ TCSYLVIO_009589 OG7 TCSYLVIO_001163 ↔ TCSYLVIO_003910 +2 more	Both
TRSC58_00890 ⚠ cholinephosphate cytidylyltransferase A	—	OG7 TCSYLVIO_004212 ↔ TCSYLVIO_011102	OG7
TRSC58_00367 ⚠ mitochondrial exoribonuclease DSS-1	—	OG7 TCSYLVIO_001759 ↔ TCSYLVIO_011102	OG7
TRSC58_06650 ⚠ ribonuclease II-like protein	—	OG7 TCSYLVIO_001759 ↔ TCSYLVIO_011102	OG7
TRSC58_04955 ⚠ hypothetical protein	—	OG6 TCSYLVIO_004284 ↔ TCSYLVIO_011102 OG7 TCSYLVIO_004284 ↔ TCSYLVIO_011102	Both
TRSC58_06996 ⚠ hypothetical protein	—	OG6 TCSYLVIO_004635 ↔ TCSYLVIO_011102 OG7 TCSYLVIO_004635 ↔ TCSYLVIO_011102	Both
TRSC58_04153 ⚠ ribonuclease	—	OG6 TCSYLVIO_004635 ↔ TCSYLVIO_011102 OG7 TCSYLVIO_004635 ↔ TCSYLVIO_011102	Both
TRSC58_01873 ⚠ spermidine synthase	—	OG6 TCSYLVIO_007160 ↔ TCSYLVIO_011102 OG7 TCSYLVIO_007160 ↔ TCSYLVIO_011102	Both
TRSC58_04532 ⚠ developmentally regulated GTP-binding protein	—	OG6 TCSYLVIO_005006 ↔ TCSYLVIO_011102 OG7 TCSYLVIO_005006 ↔ TCSYLVIO_011102	Both
TRSC58_02427 ⚠ RNA-binding protein	—	OG6 TCSYLVIO_006152 ↔ TCSYLVIO_011102 OG7 TCSYLVIO_006152 ↔ TCSYLVIO_011102	Both
TRSC58_05771 ⚠ GTP-binding protein	—	OG7 TCSYLVIO_005006 ↔ TCSYLVIO_011102	OG7
TRSC58_04396 ⚠ hypothetical protein	—	OG6 TCSYLVIO_000413 ↔ TCSYLVIO_011102 OG7 TCSYLVIO_000413 ↔ TCSYLVIO_011102	Both
TRSC58_05100 ⚠ hypothetical protein	—	OG6 TCSYLVIO_004918 ↔ TCSYLVIO_011102 OG7 TCSYLVIO_004918 ↔ TCSYLVIO_011102	Both
TRSC58_04512 ⚠ hypothetical protein	—	OG6 TCSYLVIO_002085 ↔ TCSYLVIO_011102 OG7 TCSYLVIO_002085 ↔ TCSYLVIO_011102	Both
TRSC58_04547 ⚠ pitrilysin-like metalloprotease	—	OG6 TCSYLVIO_009816 ↔ TCSYLVIO_011102 OG7 TCSYLVIO_009816 ↔ TCSYLVIO_011102	Both
TRSC58_00056 ⚠ hypothetical protein	—	OG6 TCSYLVIO_000388 ↔ TCSYLVIO_011102 OG7 TCSYLVIO_000388 ↔ TCSYLVIO_011102	Both
TRSC58_00536 ⚠ anion-transporting ATPase	—	OG6 TCSYLVIO_001663 ↔ TCSYLVIO_011102 OG7 TCSYLVIO_001663 ↔ TCSYLVIO_011102	Both
TRSC58_07255 ⚠ hypothetical protein	—	OG6 LdBPK_044360.1 ↔ LdBPK_170300.1	OG6
TRSC58_06387 ⚠ citrate synthase	—	OG6 LdBPK_044360.1 ↔ LdBPK_180700.1 OG7 LdBPK_044360.1 ↔ LdBPK_180700.1	Both
TRSC58_07112 ⚠ hypothetical protein	—	OG7 TCSYLVIO_006812 ↔ TCSYLVIO_011102	OG7
TRSC58_04594 ⚠ ankyrin repeat protein	—	OG7 TCSYLVIO_004284 ↔ TCSYLVIO_011102	OG7
TRSC58_03975 ⚠ hypothetical protein	—	OG7 TCSYLVIO_004284 ↔ TCSYLVIO_011102	OG7
TRSC58_00547 ⚠ hypothetical protein	—	OG7 LdBPK_044360.1 ↔ LdBPK_322580.1	OG7
TRSC58_06102 ⚠ hypothetical protein	—	OG7 LdBPK_044360.1 ↔ LdBPK_322580.1	OG7
TRSC58_01510 ⚠ hypothetical protein	—	OG7 LdBPK_044360.1 ↔ LdBPK_303750.1	OG7
TRSC58_00811 ⚠ hypothetical protein	—	OG7 LdBPK_044360.1 ↔ LdBPK_291030.1	OG7
TRSC58_00978 ⚠ nucleolar protein	—	OG7 LdBPK_044360.1 ↔ LdBPK_322580.1	OG7
TRSC58_06890 ⚠ hypothetical protein	—	OG7 TCSYLVIO_006812 ↔ TCSYLVIO_011102	OG7
TRSC58_07096 ⚠ cystathionine beta-synthase	—	OG6 LdBPK_044360.1 ↔ LdBPK_170300.1 OG7 LdBPK_044360.1 ↔ LdBPK_170300.1	Both
TRSC58_07193 ⚠ hypothetical protein	—	OG7 TCSYLVIO_006812 ↔ TCSYLVIO_011102	OG7
TRSC58_01499 ⚠ hypothetical protein	—	OG7 TCSYLVIO_006812 ↔ TCSYLVIO_011102	OG7
TRSC58_07003 ⚠ hypothetical protein	—	OG7 TCSYLVIO_006812 ↔ TCSYLVIO_011102	OG7
TRSC58_06424 ⚠ retrotransposon hot spot (RHS) protein	—	OG7 TCSYLVIO_006812 ↔ TCSYLVIO_011102	OG7
TRSC58_06361 ⚠ hypothetical protein	—	OG7 TCSYLVIO_006812 ↔ TCSYLVIO_011102	OG7
TRSC58_03681 ⚠ hypothetical protein	—	OG7 TCSYLVIO_008261 ↔ TCSYLVIO_011102	OG7
TRSC58_02211 ⚠ mitochondrial processing peptidase alpha subu	—	OG7 TCSYLVIO_000413 ↔ TCSYLVIO_011102	OG7
TRSC58_01940 ⚠ mitochondrial processing peptidase alpha subu	—	OG7 TCSYLVIO_000413 ↔ TCSYLVIO_011102	OG7
TRSC58_04412 ⚠ hypothetical protein	—	OG6 TCSYLVIO_003910 ↔ TCSYLVIO_003911 OG6 TCSYLVIO_003910 ↔ TCSYLVIO_009589 OG6 TCSYLVIO_003911 ↔ TCSYLVIO_009589 OG7 TCSYLVIO_003910 ↔ TCSYLVIO_003911 +2 more	Both
TRSC58_00941 ⚠ hypothetical protein	—	OG6 TCSYLVIO_006359 ↔ TCSYLVIO_011102 OG7 TCSYLVIO_006359 ↔ TCSYLVIO_011102	Both
TRSC58_05460 ⚠ hypothetical protein	—	OG6 TCSYLVIO_002337 ↔ TCSYLVIO_011102 OG7 TCSYLVIO_002337 ↔ TCSYLVIO_011102	Both
TRSC58_05427 ⚠ ethanolamine-phosphate cytidylyltransferase	—	OG6 TCSYLVIO_004212 ↔ TCSYLVIO_011102 OG7 TCSYLVIO_004212 ↔ TCSYLVIO_011102	Both
TRSC58_06324 ⚠ D-isomer specific 2-hydroxyacid dehydrogenase	—	OG6 TCSYLVIO_003910 ↔ TCSYLVIO_003911 OG6 TCSYLVIO_003910 ↔ TCSYLVIO_009589 OG6 TCSYLVIO_003911 ↔ TCSYLVIO_009589 OG7 TCSYLVIO_003910 ↔ TCSYLVIO_003911 +2 more	Both
TRSC58_06599 ⚠ enolase	—	OG6 TCSYLVIO_003910 ↔ TCSYLVIO_004545 OG6 TCSYLVIO_003911 ↔ TCSYLVIO_004545 OG6 TCSYLVIO_004545 ↔ TCSYLVIO_009589 OG7 TCSYLVIO_004545 ↔ TCSYLVIO_009589 +2 more	Both
TRSC58_04773 ⚠ serine/threonine protein kinase	—	OG6 TCSYLVIO_003910 ↔ TCSYLVIO_004423 OG6 TCSYLVIO_003911 ↔ TCSYLVIO_004423 OG6 TCSYLVIO_004423 ↔ TCSYLVIO_009589	OG6
TRSC58_06590 ⚠ D-isomer specific 2-hydroxyacid dehydrogenase	—	OG6 TCSYLVIO_003910 ↔ TCSYLVIO_003911 OG6 TCSYLVIO_003910 ↔ TCSYLVIO_009589 OG6 TCSYLVIO_003911 ↔ TCSYLVIO_009589 OG7 TCSYLVIO_003910 ↔ TCSYLVIO_003911 +2 more	Both
TRSC58_07150 ⚠ enolase	—	OG6 TCSYLVIO_003910 ↔ TCSYLVIO_004545 OG6 TCSYLVIO_003911 ↔ TCSYLVIO_004545 OG6 TCSYLVIO_004545 ↔ TCSYLVIO_009589 OG7 TCSYLVIO_004545 ↔ TCSYLVIO_009589 +2 more	Both
TRSC58_05695 ⚠ hypothetical protein	—	OG6 TCSYLVIO_001554 ↔ TCSYLVIO_011102 OG7 TCSYLVIO_001554 ↔ TCSYLVIO_011102	Both
TRSC58_05311 ⚠ D-isomer specific 2-hydroxyacid dehydrogenase	—	OG6 TCSYLVIO_003910 ↔ TCSYLVIO_003911 OG6 TCSYLVIO_003910 ↔ TCSYLVIO_009589 OG6 TCSYLVIO_003911 ↔ TCSYLVIO_009589 OG7 TCSYLVIO_003910 ↔ TCSYLVIO_003911 +2 more	Both
TRSC58_05192 ⚠ hypothetical protein	—	OG6 TCSYLVIO_001376 ↔ TCSYLVIO_011102 OG7 TCSYLVIO_001376 ↔ TCSYLVIO_011102	Both
TRSC58_06569 ⚠ hypothetical protein	—	OG6 TCSYLVIO_002348 ↔ TCSYLVIO_011102 OG7 TCSYLVIO_002348 ↔ TCSYLVIO_011102	Both

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