TRSC58_06387

citrate synthase

Trypanosoma rangeli SC58 OG6: OG6_101425 OG7: OG7_0003359 46 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 46 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
TRSC58_02968 ⚠ hypothetical protein	—	OG6 LdBPK_180700.1 ↔ LdBPK_303750.1 OG7 LdBPK_180700.1 ↔ LdBPK_303750.1	Both
TRSC58_06787 ⚠ D-isomer specific 2-hydroxyacid dehydrogenase	—	OG6 LdBPK_044360.1 ↔ LdBPK_180700.1 OG7 LdBPK_044360.1 ↔ LdBPK_180700.1	Both
TRSC58_06590 ⚠ D-isomer specific 2-hydroxyacid dehydrogenase	—	OG6 LdBPK_044360.1 ↔ LdBPK_180700.1 OG7 LdBPK_044360.1 ↔ LdBPK_180700.1	Both
TRSC58_06324 ⚠ D-isomer specific 2-hydroxyacid dehydrogenase	—	OG6 LdBPK_044360.1 ↔ LdBPK_180700.1 OG7 LdBPK_044360.1 ↔ LdBPK_180700.1	Both
TRSC58_01347 ⚠ alanine aminotransferase	—	OG6 Tb927.1.3950 ↔ Tb927.10.13430 OG7 Tb927.1.3950 ↔ Tb927.10.13430	Both
TRSC58_06529 ⚠ hypothetical protein	—	OG6 LdBPK_180700.1 ↔ LdBPK_350680.1 OG7 LdBPK_180700.1 ↔ LdBPK_350680.1	Both
TRSC58_05352 ⚠ P-nitrophenylphosphatase	—	OG6 LdBPK_180700.1 ↔ LdBPK_312410.1 OG7 LdBPK_180700.1 ↔ LdBPK_312410.1	Both
TRSC58_06078 ⚠ hypothetical protein	—	OG6 LdBPK_180700.1 ↔ LdBPK_230580.1 OG6 LdBPK_180700.1 ↔ LdBPK_230880.1 OG7 LdBPK_180700.1 ↔ LdBPK_230580.1 OG7 LdBPK_180700.1 ↔ LdBPK_230880.1	Both
TRSC58_03195 ⚠ hypothetical protein	—	OG6 LdBPK_180700.1 ↔ LdBPK_291030.1 OG7 LdBPK_180700.1 ↔ LdBPK_291030.1	Both
TRSC58_03917 ⚠ hypothetical protein	—	OG6 LdBPK_180700.1 ↔ LdBPK_367300.1 OG7 LdBPK_180700.1 ↔ LdBPK_367300.1	Both
TRSC58_04133 ⚠ hypothetical protein	—	OG6 LdBPK_180700.1 ↔ LdBPK_322580.1 OG7 LdBPK_180700.1 ↔ LdBPK_322580.1	Both
TRSC58_02219 ⚠ hypothetical protein	—	OG6 LdBPK_180700.1 ↔ LdBPK_350680.1 OG7 LdBPK_180700.1 ↔ LdBPK_350680.1	Both
TRSC58_04412 ⚠ hypothetical protein	—	OG6 LdBPK_044360.1 ↔ LdBPK_180700.1 OG7 LdBPK_044360.1 ↔ LdBPK_180700.1	Both
TRSC58_03629 ⚠ generic methyltransferase	—	OG6 LdBPK_180700.1 ↔ LdBPK_291030.1 OG7 LdBPK_180700.1 ↔ LdBPK_291030.1	Both
TRSC58_06230 ⚠ acetyl-CoA synthetase	—	OG6 LdBPK_180700.1 ↔ LdBPK_230580.1 OG6 LdBPK_180700.1 ↔ LdBPK_230880.1 OG7 LdBPK_180700.1 ↔ LdBPK_230580.1 OG7 LdBPK_180700.1 ↔ LdBPK_230880.1	Both
TRSC58_06433 ⚠ 4-nitrophenyl phosphatase	—	OG6 LdBPK_180700.1 ↔ LdBPK_312410.1 OG7 LdBPK_180700.1 ↔ LdBPK_312410.1	Both
TRSC58_03770 ⚠ hypothetical protein	—	OG6 LdBPK_180700.1 ↔ LdBPK_201330.1 OG7 LdBPK_180700.1 ↔ LdBPK_201330.1	Both
TRSC58_01227 ⚠ glucose-6-phosphate isomerase, glycosomal	—	OG6 Tb927.1.3830 ↔ Tb927.10.13430 OG7 Tb927.1.3830 ↔ Tb927.10.13430	Both
TRSC58_00978 ⚠ nucleolar protein	—	OG7 LdBPK_180700.1 ↔ LdBPK_322580.1	OG7
TRSC58_00811 ⚠ hypothetical protein	—	OG7 LdBPK_180700.1 ↔ LdBPK_291030.1	OG7
TRSC58_01510 ⚠ hypothetical protein	—	OG7 LdBPK_180700.1 ↔ LdBPK_303750.1	OG7
TRSC58_06102 ⚠ hypothetical protein	—	OG7 LdBPK_180700.1 ↔ LdBPK_322580.1	OG7
TRSC58_00547 ⚠ hypothetical protein	—	OG7 LdBPK_180700.1 ↔ LdBPK_322580.1	OG7
TRSC58_03736 ⚠ kynureninase	—	OG6 Tb927.10.13430 ↔ Tb927.9.2010 OG7 Tb927.10.13430 ↔ Tb927.9.2010	Both
TRSC58_02154 ⚠ 6-phosphogluconate dehydrogenase, decarboxyla	—	OG6 Tb927.10.13430 ↔ Tb927.9.12110 OG7 Tb927.10.13430 ↔ Tb927.9.12110	Both
TRSC58_06047 ⚠ fumarate hydratase	—	OG6 Tb927.10.13430 ↔ Tb927.11.5050 OG7 Tb927.10.13430 ↔ Tb927.11.5050	Both
TRSC58_00190 ⚠ 3-hydroxy-3-methylglutaryl-CoA reductase	—	OG6 Tb927.10.13430 ↔ Tb927.6.4540 OG7 Tb927.10.13430 ↔ Tb927.6.4540	Both
TRSC58_03074 ⚠ cystathionine beta-synthase	—	OG6 LdBPK_170300.1 ↔ LdBPK_180700.1 OG7 LdBPK_170300.1 ↔ LdBPK_180700.1	Both
TRSC58_01180 ⚠ nucleoside diphosphate kinase	—	OG6 Tb927.10.13430 ↔ Tb927.11.16130 OG7 Tb927.10.13430 ↔ Tb927.11.16130	Both
TRSC58_04533 ⚠ fumarate hydratase	—	OG6 Tb927.10.13430 ↔ Tb927.11.5050 OG7 Tb927.10.13430 ↔ Tb927.11.5050	Both
TRSC58_06174 ⚠ isocitrate dehydrogenase	—	OG6 Tb927.10.13430 ↔ Tb927.11.900 OG7 Tb927.10.13430 ↔ Tb927.11.900	Both
TRSC58_04698 ⚠ glycerol kinase, glycosomal	—	OG6 Tb927.10.13430 ↔ Tb927.9.12570 OG7 Tb927.10.13430 ↔ Tb927.9.12570	Both
TRSC58_07150 ⚠ enolase	—	OG6 Tb927.10.13430 ↔ Tb927.10.2890 OG7 Tb927.10.13430 ↔ Tb927.10.2890	Both
TRSC58_06599 ⚠ enolase	—	OG6 Tb927.10.13430 ↔ Tb927.10.2890 OG7 Tb927.10.13430 ↔ Tb927.10.2890	Both
TRSC58_02143 ⚠ nucleoside diphosphate kinase	—	OG6 Tb927.10.13430 ↔ Tb927.11.16130 OG7 Tb927.10.13430 ↔ Tb927.11.16130	Both
TRSC58_05439 ⚠ cystathionine beta-synthase	—	OG6 LdBPK_170300.1 ↔ LdBPK_180700.1 OG7 LdBPK_170300.1 ↔ LdBPK_180700.1	Both
TRSC58_01161 ⚠ hypothetical protein	—	OG6 Tb927.10.13430 ↔ Tb927.8.6110 OG7 Tb927.10.13430 ↔ Tb927.8.6110	Both
TRSC58_07032 ⚠ aspartate carbamoyltransferase	—	OG6 Tb927.10.13430 ↔ Tb927.5.3820 OG7 Tb927.10.13430 ↔ Tb927.5.3820	Both
TRSC58_03256 ⚠ methylthioadenosine phosphorylase	—	OG6 Tb927.10.13430 ↔ Tb927.7.7040 OG7 Tb927.10.13430 ↔ Tb927.7.7040	Both
TRSC58_07096 ⚠ cystathionine beta-synthase	—	OG6 LdBPK_170300.1 ↔ LdBPK_180700.1 OG7 LdBPK_170300.1 ↔ LdBPK_180700.1	Both
TRSC58_07255 ⚠ hypothetical protein	—	OG6 LdBPK_170300.1 ↔ LdBPK_180700.1	OG6
TRSC58_03443 ⚠ cytidine triphosphate synthase	—	OG6 Tb927.1.1240 ↔ Tb927.10.13430 OG7 Tb927.1.1240 ↔ Tb927.10.13430	Both
TRSC58_01304 ⚠ hypothetical protein	—	OG6 Tb927.1.1240 ↔ Tb927.10.13430 OG7 Tb927.1.1240 ↔ Tb927.10.13430	Both
TRSC58_06784 ⚠ cytidine triphosphate synthase	—	OG6 Tb927.1.1240 ↔ Tb927.10.13430 OG7 Tb927.1.1240 ↔ Tb927.10.13430	Both
TRSC58_00434 ⚠ hypothetical protein	—	OG6 LdBPK_140260.1 ↔ LdBPK_180700.1 OG7 LdBPK_140260.1 ↔ LdBPK_180700.1	Both
TRSC58_05311 ⚠ D-isomer specific 2-hydroxyacid dehydrogenase	—	OG6 LdBPK_044360.1 ↔ LdBPK_180700.1 OG7 LdBPK_044360.1 ↔ LdBPK_180700.1	Both