TcCLB.504153.330

Nucleoporin NUP59
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_147559 OG7: OG7_0043654 17 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Network view all shared interactors, plus up to 150 more
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Interactions 17 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.507257.180 ⚠
hypothetical protein
— OG7
TcCLB.507811.30 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
TcCLB.511571.10 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
TcCLB.506213.120 ⚠
ATP-dependent RNA helicase HEL67
— OG7
TcCLB.510741.180 ⚠
ATP-dependent RNA helicase, putative
— OG7
TcCLB.503595.19 ⚠
ATP-dependent DEAD/H RNA helicase, putative (
— OG7
TcCLB.508973.50 ⚠
ATP-dependent RNA helicase DBP2B, putative
— OG7
TcCLB.511571.40
hypothetical protein, conserved
— OG7
TcCLB.511627.110 ⚠
heat shock protein DNAJ, putative
— OG7
TcCLB.509443.20
mitochondrial RNA binding protein 1, putative
— Both
TcCLB.511531.9 ⚠
chaperone DNAJ protein, putative
— OG7
TcCLB.510165.10 ⚠
heat shock protein DNAJ, putative
— OG7
TcCLB.508179.10 ⚠
DnaJ chaperone protein, putative
— OG7
TcCLB.510241.70 ⚠
heat shock protein, putative
— OG7
TcCLB.509233.80 ⚠
heat shock protein DNAJ, putative
— OG7
TcCLB.511801.60 ⚠
DEAD-box ATP-dependent RNA helicase, mitochon
— Both
TcCLB.510743.100 ⚠
chaperone DNAJ protein, putative
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.