TcCLB.506213.120

ATP-dependent RNA helicase HEL67
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_100461 OG7: OG7_0000120 81 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 81 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.509551.64 ⚠
small nuclear ribonucleoprotein Sm-F, putativ
— Both
TcCLB.509965.30 ⚠
small nuclear ribonucleoprotein Sm-E, putativ
— OG7
TcCLB.510091.70 ⚠
U6 snRNA-associated Sm-like protein LSm8, put
— OG7
TcCLB.506893.25 ⚠
U6 snRNA-associated Sm-like protein LSm6p
— OG7
TcCLB.503479.49 ⚠
U6 snRNA-associated Sm-like protein LSm7p
— OG7
TcCLB.506249.20 ⚠
protein transport protein Sec23A, putative
— OG7
TcCLB.503793.10 ⚠
2-oxoglutarate dehydrogenase subunit, putativ
— OG7
TcCLB.511555.80 ⚠
ribonucleoside-diphosphate reductase small ch
— OG7
TcCLB.504097.10 ⚠
RNA editing complex protein MP61, putative
— OG7
TcCLB.510431.280 ⚠
RNA editing complex protein MP46, putative
— OG7
TcCLB.506363.80 ⚠
N-acyl-L-amino acid amidohydrolase, putative,
— OG7
TcCLB.506363.70 ⚠
amidohydrolase, putative
— OG7
TcCLB.506363.90 ⚠
amidohydrolase, putative
— OG7
TcCLB.507483.60 ⚠
translation-associated element 2, putative
— OG7
TcCLB.510295.20 ⚠
MP24, putative
— OG7
TcCLB.507611.398 ⚠
RNA editing complex protein MP63, putative (f
— OG7
TcCLB.506933.107 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511585.20 ⚠
KREL1
— OG7
TcCLB.503579.150 ⚠
RNA editing complex protein MP57, putative, R
— OG7
TcCLB.510857.40 ⚠
RNA-editing complex protein, putative
— OG7
TcCLB.504643.40 ⚠
U6 snRNA-associated Sm-like protein LSm4, put
— OG7
TcCLB.504075.10 ⚠
kinetoplast poly(A) polymerase 1
— OG7
TcCLB.510241.70 ⚠
heat shock protein, putative
— OG7
TcCLB.511627.110 ⚠
heat shock protein DNAJ, putative
— OG7
TcCLB.507257.180 ⚠
hypothetical protein
— OG7
TcCLB.511531.9 ⚠
chaperone DNAJ protein, putative
— OG7
TcCLB.511303.60 ⚠
eukaryotic translation initiation factor 3 su
— OG7
TcCLB.504163.110 ⚠
n-alpha-acetyltransferase 15, NatA auxiliary
— OG7
TcCLB.510165.10 ⚠
heat shock protein DNAJ, putative
— OG7
TcCLB.503715.10 ⚠
splicing factor TSR1, putative
— OG7
TcCLB.506211.60 ⚠
RNA-binding protein, putative
— OG7
TcCLB.508179.10 ⚠
DnaJ chaperone protein, putative
— OG7
TcCLB.510743.100 ⚠
chaperone DNAJ protein, putative
— OG7
TcCLB.511575.100 ⚠
protein transport protein SEC23, putative
— OG7
TcCLB.506963.10 ⚠
60S ribosomal protein L10a, putative
— OG7
TcCLB.506211.70 ⚠
RNA-binding protein, putative
— OG7
TcCLB.504153.330 ⚠
Nucleoporin NUP59
— OG7
TcCLB.509233.80 ⚠
heat shock protein DNAJ, putative
— OG7
TcCLB.507841.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506135.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510717.30 ⚠
2-oxoglutarate dehydrogenase E1 component, pu
— OG7
TcCLB.408345.20 ⚠
2-oxoglutarate dehydrogenase subunit, putativ
— OG7
TcCLB.506363.110 ⚠
RNA editing ligase, putative, RNA editing com
— OG7
TcCLB.508813.15 ⚠
heat shock protein 70, putative (fragment)
— OG6
TcCLB.504929.5 ⚠
zinc finger CCCH domain containing protein 11
— OG7
TcCLB.510431.220 ⚠
ribosome assembly protein RRB1, putative
— OG7
TcCLB.511369.5 ⚠
elongation factor 1-alpha, putative (fragment
— OG7
TcCLB.506943.160 ⚠
eukaryotic translation initiation factor 3 su
— OG7
TcCLB.506289.60 ⚠
Cupin-like domain containing protein, putativ
— OG7
TcCLB.504247.40 ⚠
RNA-editing nuclease 1
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.