TcCLB.511555.80

ribonucleoside-diphosphate reductase small chain, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_100537 OG7: OG7_0003661 87 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 87 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.511369.30 ⚠
elongation factor 1-alpha, putative
— OG7
TcCLB.510105.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508323.84 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
TcCLB.510231.20
hypothetical protein
— OG7
TcCLB.506635.40 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
TcCLB.511353.10 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
TcCLB.506885.416 ⚠
regulator of chromosome condensation (RCC1),
— OG7
TcCLB.506363.80 ⚠
N-acyl-L-amino acid amidohydrolase, putative,
— OG7
TcCLB.511369.10 ⚠
elongation factor 1-alpha, putative
— OG7
TcCLB.508949.4 ⚠
elongation factor 1-alpha (ef-1-alpha), putat
— OG7
TcCLB.511369.20 ⚠
elongation factor 1-alpha, putative
— OG7
TcCLB.508973.50 ⚠
ATP-dependent RNA helicase DBP2B, putative
— OG7
TcCLB.511369.5 ⚠
elongation factor 1-alpha, putative (fragment
— OG7
TcCLB.506739.50 ⚠
ATP-dependent protease ATPase subunit HslU1,
— Both
TcCLB.506363.70 ⚠
amidohydrolase, putative
— Both
TcCLB.506363.90 ⚠
amidohydrolase, putative
— Both
TcCLB.511691.10 ⚠
cysteine synthase, cystathionine beta-synthas
— Both
TcCLB.510381.10 ⚠
cystathionine beta-synthase, putative
— Both
TcCLB.507165.50 ⚠
cysteine synthase, putative
— OG6
TcCLB.508241.140 ⚠
serine sulfhydrylase, cysteine synthase, cyst
— Both
TcCLB.508241.149 ⚠
cystathionine beta-synthase, putative (fragme
— Both
TcCLB.509149.9 ⚠
cystathionine beta-synthase, serine sulfhydry
— Both
TcCLB.506375.10 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
TcCLB.504427.10 ⚠
trypanothione synthetase, putative
— OG7
TcCLB.486465.9 ⚠
cysteine peptidase, Clan CA, family C51, puta
— OG7
TcCLB.508771.10 ⚠
cysteine peptidase, Clan CA, family C51, puta
— OG7
TcCLB.508277.160 ⚠
glutaminyl-tRNA synthetase, putative
— OG7
TcCLB.508771.20 ⚠
cysteine peptidase, Clan CA, family C51, puta
— OG7
TcCLB.506249.20 ⚠
protein transport protein Sec23A, putative
— OG7
TcCLB.507811.30 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
TcCLB.511571.10 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
TcCLB.508211.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510593.10 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
TcCLB.447925.10 ⚠
cystathionine beta-synthase, putative (fragme
— OG6
TcCLB.507841.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506213.120 ⚠
ATP-dependent RNA helicase HEL67
— OG7
TcCLB.506773.180 ⚠
regulator of chromatin condensation, putative
— OG7
TcCLB.508439.30 ⚠
regulator of chromosome condensation 1-like p
— OG7
TcCLB.503479.70 ⚠
hook complex protein, conserved
— OG7
TcCLB.510741.180 ⚠
ATP-dependent RNA helicase, putative
— OG7
TcCLB.503595.19 ⚠
ATP-dependent DEAD/H RNA helicase, putative (
— OG7
TcCLB.508169.69 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
TcCLB.508213.9 ⚠
regulator of chromosome condensation, putativ
— OG7
TcCLB.506375.60 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
TcCLB.503899.90
asparagine synthetase a, putative
— Both
TcCLB.509591.20 ⚠
kinetoplastid-specific phospho-protein phosph
— OG6
TcCLB.504213.20
Protein of unknown function (DUF1253), putati
— Both
TcCLB.504213.80
threonine synthase, putative
— Both
TcCLB.511731.60 ⚠
glutamyl-tRNA synthetase, putative
— Both
TcCLB.509099.50 ⚠
trypanothione synthetase
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.