TcCLB.508771.10

cysteine peptidase, Clan CA, family C51, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_115782 OG7: OG7_0010828 51 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 51 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.503899.90 ⚠
asparagine synthetase a, putative
— OG7
TcCLB.510315.10 ⚠
inosine-adenosine-guanosine-nucleosidehydrola
— OG7
TcCLB.506775.80 ⚠
14-3-3 protein 2, putative
— OG7
TcCLB.509099.30 ⚠
paraflagellar rod protein 5, putative
— OG7
TcCLB.511581.10 ⚠
fatty acyl CoA synthetase 2, putative
— OG7
TcCLB.506829.110 ⚠
fatty acyl CoA synthetase 2, putative
— OG7
TcCLB.511581.20 ⚠
fatty acyl CoA syntetase 1 (fragment)
— OG7
TcCLB.506829.100 ⚠
fatty acyl CoA syntetase 1, putative
— OG7
TcCLB.504033.130 ⚠
spermidine synthase, putative
— OG7
TcCLB.503855.20 ⚠
spermidine synthase, putative
— OG7
TcCLB.509151.130 ⚠
deoxyuridine triphosphatase, putative, dUTP d
— OG7
TcCLB.511579.9 ⚠
fatty acyl CoA syntetase 1, putative (fragmen
— OG7
TcCLB.507925.40 ⚠
pyridoxal kinase, putative
— OG7
TcCLB.508647.280 ⚠
malic enzyme
— OG7
TcCLB.504213.80 ⚠
threonine synthase, putative
— OG7
TcCLB.503575.50 ⚠
fatty acyl CoA synthetase, putative
— OG7
TcCLB.508241.149 ⚠
cystathionine beta-synthase, putative (fragme
— OG7
TcCLB.508241.140 ⚠
serine sulfhydrylase, cysteine synthase, cyst
— OG7
TcCLB.510381.10 ⚠
cystathionine beta-synthase, putative
— OG7
TcCLB.511691.10 ⚠
cysteine synthase, cystathionine beta-synthas
— OG7
TcCLB.511691.20 ⚠
cystathionine beta-synthase, cysteine synthas
— OG7
TcCLB.509149.9 ⚠
cystathionine beta-synthase, serine sulfhydry
— OG7
TcCLB.506825.210 ⚠
Putative Phosphatase/Protein of unknown funct
— OG7
TcCLB.511577.50 ⚠
endo-beta-N-acetylglucosaminidase, putative
— OG7
TcCLB.511555.80 ⚠
ribonucleoside-diphosphate reductase small ch
— OG7
TcCLB.504427.110 ⚠
acetyl-CoA synthetase, putative
— OG7
TcCLB.503855.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506503.69 ⚠
glycosomal malate dehydrogenase, putative
— OG7
TcCLB.507883.100 ⚠
malate dehydrogenase, putative
— OG7
TcCLB.506937.10 ⚠
cytosolic malate dehydrogenase, putative
— OG7
TcCLB.508647.270 ⚠
malic enzyme, putative
— OG7
TcCLB.504431.100 ⚠
guanine deaminase, putative
— OG7
TcCLB.506947.90 ⚠
adenylate kinase, putative
— OG7
TcCLB.503713.10 ⚠
histone chaperone ASF1B
— OG7
TcCLB.506351.80 ⚠
serine peptidase, clan SC, family S9A-like pr
— OG7
TcCLB.506825.190 ⚠
hypothetical protein
— OG7
TcCLB.508781.120 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507165.50 ⚠
cysteine synthase, putative
— OG7
TcCLB.503479.30 ⚠
adenylate kinase 1
— OG7
TcCLB.511589.130 ⚠
14-3-3 protein 1, putative
— OG7
TcCLB.510751.4 ⚠
aminopeptidase P, putative
— OG7
TcCLB.434945.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510243.50 ⚠
UMP/CMP kinase, putative
— OG7
TcCLB.441401.10 ⚠
imidazolonepropienase, putative
— OG7
TcCLB.511559.20 ⚠
Uncharacterised protein family (UPF0160), put
— OG7
TcCLB.506685.30 ⚠
thymidylate kinase, putative
— OG7
TcCLB.511557.10 ⚠
oligopeptidase b
— OG7
TcCLB.510749.99 ⚠
aminopeptidase P, putative
— OG7
TcCLB.509137.30 ⚠
imidazolonepropionase, putative
— OG7
TcCLB.503971.40 ⚠
translation initiation factor 2 subunit, puta
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.