TcCLB.506503.69

glycosomal malate dehydrogenase, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_133291 OG7: OG7_0004751 55 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 55 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.504033.130 ⚠
spermidine synthase, putative
— OG7
TcCLB.503855.20 ⚠
spermidine synthase, putative
— OG7
TcCLB.508383.10 ⚠
Present in the outer mitochondrial membrane p
— OG7
TcCLB.505989.82 ⚠
ruvB-like DNA helicase, putative
— OG7
TcCLB.511395.30 ⚠
protein phosphatase 2A, regulatory subunit B,
— OG7
TcCLB.506363.90 ⚠
amidohydrolase, putative
— OG7
TcCLB.506363.70 ⚠
amidohydrolase, putative
— OG7
TcCLB.506351.80 ⚠
serine peptidase, clan SC, family S9A-like pr
— OG7
TcCLB.506363.80 ⚠
N-acyl-L-amino acid amidohydrolase, putative,
— OG7
TcCLB.504507.5 ⚠
trypanothione reductase, putative (fragment)
— OG7
TcCLB.511557.10 ⚠
oligopeptidase b
— OG7
TcCLB.484299.10 ⚠
trypanothione reductase, putative
— OG7
TcCLB.511303.160 ⚠
sodium/hydrogen exchanger, putative
— OG7
TcCLB.506239.20 ⚠
Metallopeptidase family M24, putative
— OG7
TcCLB.506211.200 ⚠
metallo-peptidase, Clan MG, Family M24
— OG7
TcCLB.510611.79 ⚠
Present in the outer mitochondrial membrane p
— OG7
TcCLB.509965.330 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507559.80 ⚠
deoxyribose-phosphate aldolase, putative
— OG7
TcCLB.506411.10 ⚠
metallo-peptidase, clan MA(E), family M3, put
— OG7
TcCLB.504147.80 ⚠
mitochondrial intermediate peptidase, putativ
— OG7
TcCLB.504153.180 ⚠
UDP-N-acetylglucosamine pyrophosphorylase, pu
— OG7
TcCLB.511199.9 ⚠
ATP-dependent RNA helicase FAL1, putative (fr
— OG7
TcCLB.511139.40 ⚠
ATP-dependent RNA helicase SUB2, putative (fr
— OG7
TcCLB.511585.190 ⚠
Eukaryotic initiation factor 4A-1
— OG7
TcCLB.482471.19 ⚠
ATP-dependent RNA helicase SUB2, putative (fr
— OG7
TcCLB.505009.30 ⚠
kinetoplastid-specific phospho-protein phosph
— OG7
TcCLB.506863.80 ⚠
ApaH-like phosphatase ALPH1, putative
— OG7
TcCLB.510143.10 ⚠
FHA domain containing protein, putative
— OG7
TcCLB.503779.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511733.130 ⚠
chaperonin HSP60, putative (fragment)
— OG7
TcCLB.508207.70 ⚠
Adenine phosphoribosyltransferase, putative
— OG7
TcCLB.508771.20 ⚠
cysteine peptidase, Clan CA, family C51, puta
— OG7
TcCLB.507641.290 ⚠
heat shock protein 60, chaperonin HSP60, mito
— OG7
TcCLB.507641.280 ⚠
chaperonin HSP60, mitochondrial precursor, gr
— OG7
TcCLB.506937.10 ⚠
cytosolic malate dehydrogenase, putative
— OG7
TcCLB.508647.200 ⚠
triosephosphate isomerase
— OG7
TcCLB.507641.300 ⚠
groELprotein, chaperonin HSP60, mitochondrial
— OG7
TcCLB.509099.50 ⚠
trypanothione synthetase
— OG7
TcCLB.439653.10 ⚠
NADH-dependent fumarate reductase, putative
— OG7
TcCLB.511047.40 ⚠
NADH-cytochrome b5 reductase, putative
— OG7
TcCLB.508771.10 ⚠
cysteine peptidase, Clan CA, family C51, puta
— OG7
TcCLB.506775.170 ⚠
NADH-cytochrome b5 reductase, putative
— OG7
TcCLB.510877.60 ⚠
ruvB-like DNA helicase, putative
— OG7
TcCLB.509157.279 ⚠
Chaperonin HSP60, mitochondrial
— OG7
TcCLB.507925.40 ⚠
pyridoxal kinase, putative
— OG7
TcCLB.510565.30 ⚠
cytochrome c oxidase subunit V, putative
— OG7
TcCLB.503893.70 ⚠
reductase, putative
— OG7
TcCLB.510315.10 ⚠
inosine-adenosine-guanosine-nucleosidehydrola
— OG7
TcCLB.486465.9 ⚠
cysteine peptidase, Clan CA, family C51, puta
— OG7
TcCLB.504427.10 ⚠
trypanothione synthetase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.