TcCLB.507559.80

deoxyribose-phosphate aldolase, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_102064 OG7: OG7_0007190 51 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 51 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.511351.41 ⚠
choline/carnitine O-acyltransferase, putative
— OG7
TcCLB.507089.270
dihydrolipoyl dehydrogenase, putative
— Both
TcCLB.506221.30 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.420989.10 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.509007.70 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.506659.39 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.506925.150 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.503989.60 ⚠
protein phosphatase 2C, putative (fragment)
— OG7
TcCLB.511303.40 ⚠
carnitine O-acetyltransferase, putative
— OG7
TcCLB.506739.200 ⚠
pyruvate dehydrogenase phosphatase
— OG7
TcCLB.507211.10 ⚠
choline/carnitine O-acyltransferase, putative
— OG7
TcCLB.510291.30 ⚠
protein phosphatase 2C-like, putative
— OG7
TcCLB.511353.4 ⚠
choline/carnitine O-acyltransferase, putative
— OG7
TcCLB.504147.30
Protein of unknown function (DUF2870), putati
— Both
TcCLB.511625.40 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.506779.170 ⚠
haloacid dehalogenase hydrolase, putative
— OG7
TcCLB.505009.30 ⚠
kinetoplastid-specific phospho-protein phosph
— OG7
TcCLB.506239.20 ⚠
Metallopeptidase family M24, putative
— OG7
TcCLB.511199.9 ⚠
ATP-dependent RNA helicase FAL1, putative (fr
— OG7
TcCLB.506503.69 ⚠
glycosomal malate dehydrogenase, putative
— OG7
TcCLB.503779.30
hypothetical protein, conserved
— OG7
TcCLB.506863.80 ⚠
ApaH-like phosphatase ALPH1, putative
— OG7
TcCLB.511585.190 ⚠
Eukaryotic initiation factor 4A-1
— OG7
TcCLB.510143.10
FHA domain containing protein, putative
— OG7
TcCLB.507883.100 ⚠
malate dehydrogenase, putative
— OG7
TcCLB.504147.80 ⚠
mitochondrial intermediate peptidase, putativ
— OG7
TcCLB.503841.70
aspartate aminotransferase, putative
— Both
TcCLB.507883.109 ⚠
mitochondrial malate dehydrogenase, putative
— Both
TcCLB.506857.60
peptidyl-prolyl cis-trans isomerase, putative
— OG6
TcCLB.504153.180
UDP-N-acetylglucosamine pyrophosphorylase, pu
— Both
TcCLB.506211.200 ⚠
metallo-peptidase, Clan MG, Family M24
— Both
TcCLB.482471.19 ⚠
ATP-dependent RNA helicase SUB2, putative (fr
— Both
TcCLB.511395.30
protein phosphatase 2A, regulatory subunit B,
— Both
TcCLB.510953.40
hypothetical protein, conserved
— Both
TcCLB.508085.10
GMP synthase, putative
— Both
TcCLB.504033.130 ⚠
spermidine synthase, putative
— Both
TcCLB.503855.20 ⚠
spermidine synthase, putative
— Both
TcCLB.503477.20
transaldolase, putative
— Both
TcCLB.506411.10 ⚠
metallo-peptidase, clan MA(E), family M3, put
— Both
TcCLB.511139.40 ⚠
ATP-dependent RNA helicase SUB2, putative (fr
— Both
TcCLB.506635.60
pyroglutamyl-peptidase I, putative
— Both
TcCLB.507993.390
pyruvate kinase 2, putative
— Both
TcCLB.482369.29
arginine kinase (fragment)
— Both
TcCLB.506931.10 ⚠
haloacid dehalogenase-like hydrolase, putativ
— Both
TcCLB.510719.260
ATP-dependent protease subunit HslV, putative
— Both
TcCLB.509203.30
hd phosphohydrolase family protein
— Both
TcCLB.509979.150
nitrilase, putative
— Both
TcCLB.506405.10
phosphomannomutase-like protein, putative
— Both
TcCLB.511573.40
Mitogen-activated protein kinase 10, putative
— OG6
TcCLB.506525.80
N-myristoyl transferase, putative
— Both
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.